Index | Ligand Name | Structure | PDB code | Compound Potency nM |
1 | 4jr | Structure of Prolyl Hydroxylase Domain-containing Protein (PHD) with Inhibitors | 4jzr | 15.8 |
2 | a1z | HIF prolyl hydroxylase 2 (PHD2/ EGLN1) in complex with Vadadustat | 5ox6 | 29 |
3 | qnm | HIF prolyl hydroxylase 2 (PHD2/ EGLN1) in complex with Mn(II) and 2-(4-hydroxy-2-oxo-1,2-dihydroquinoline-3-carboxamido)acetic acid | 4bqw | 33 |
4 | un9 | S-nitrosylated PHD2 (NO exposed) in complex with Fe(II) and UN9 | 2y34 | 80 |
5 | un9 | HIF prolyl hydroxylase 2 (PHD2/ EGLN1) in complex with Mn(II) and N-[(1-chloro-4-hydroxyisoquinolin-3-yl)carbonyl]glycine (IOX3/UN9) | 4bqx | 300 |
6 | fnt | HIF prolyl hydroxylase 2 (PHD2/ EGLN1) in complex with Fe(II) and N-[(1-chloro-4-hydroxyisoquinolin-3-yl)carbonyl]alanine | 4bqy | 1100 |
7 | 4hg | Cellular Oxygen Sensing: Crystal Structure of Hypoxia-Inducible Factor Prolyl Hydroxylase (PHD2) | 2g19 | 1400 |
8 | 42z | PHD2-R717 with 40787422 | 3oui | 1.26e+004 |