| Index | Ligand Name | Structure | PDB code | Compound Potency nM |
| 1 | xnn | X-ray Structure of ketohexokinase in complex with a pyrimidopyrimidine analog 3 | 3qai | 8 |
| 2 | xnb | X-ray Structure of ketohexokinase in complex with a pyrimidopyrimidine analog 1 | 3q92 | 12 |
| 3 | xna | X-ray Structure of ketohexokinase in complex with a pyrimidopyrimidine analog 2 | 3qa2 | 210 |
| 4 | a4j | Structure of human Ketohexokinase complexed with hits from fragment screening | 5wbz | 390 |
| 5 | a4g | Structure of human Ketohexokinase complexed with hits from fragment screening | 5wbm | 2e+004 |