| Index | Ligand Name | Structure | PDB code | Compound Potency nM |
| 1 | 2d6 | Co-crystal structure of tankyrase 1 with compound 49 | 4mt9 | 0.1 |
| 2 | 2c6 | Crystal structure of tankyrase 1 with compound 22 | 4msg | 0.1 |
| 3 | 2gy | Co-crystal structure of tankyrase 1 with compound 4 [(4S)-3-{trans-4-[6-amino-5-(pyrimidin-2-yl)pyridin-3-yl]cyclohexyl}-5,5-dimethyl-4-phenyl-1,3-oxazolidin-2-one] | 4n4v | 2 |
| 4 | 1xq | TANKYRASE-1 complexed with small molecule inhibitor 2-[4-(4-fluorobenzoyl)piperidin-1-yl]-N-[(4-oxo-3,5,7,8-tetrahydro-4H-pyrano[4,3-d]pyrimidin-2-yl)methyl]-N-(thiophen-2-ylmethyl)acetamide | 4li8 | 7.5 |
| 5 | 1dy | Crystal structure of tankyrase 1 with compound 4 | 4i9i | 8 |
| 6 | 5n2 | Tankyrase 1 with Phthalazinone 1 | 5ece | 9 |
| 7 | t40 | X-ray crystal structure of human TNKS in complex with a small molecule inhibitor | 4uuh | 17 |
| 8 | k4e | Co-crystal structure of tnks1 with compound 52 [N~2-(5-chloro-2-methoxyphenyl)-N-[trans-4-(2-oxo-2,3-dihydro-1H-benzimidazol-1-yl)cyclohexyl]glycinamide] | 4k4e | 24 |
| 9 | k56 | Crystal Structure of human Tankyrase-1 bound to K-756 | 5ety | 31 |
| 10 | 2gv | Co-crystal structure of tankyrase 1 with compound 3 [(4S)-3-{4-[6-amino-5-(pyrimidin-2-yl)pyridin-3-yl]phenyl}-5,5-dimethyl-4-phenyl-1,3-oxazolidin-2-one] | 4n4t | 49 |
| 11 | 2c8 | Co-crystal structure of tankyrase 1 with compound 34 | 4msk | 63 |
| 12 | 1xo | TANKYRASE-1 Complexed with small molecule inhibitor N-[(4-oxo-3,4-dihydroquinazolin-2-yl)methyl]-3-phenyl-N-(thiophen-2-ylmethyl)propanamide | 4li6 | 106 |
| 13 | 2gu | Co-crystal structure of tankyrase 1 with compound 2 (5-(2-aminoquinazolin-6-yl)-N-(4,4-dimethyl-2-oxo-1,2,3,4-tetrahydroquinolin-7-yl)-2-fluorobenzamide) | 4n3r | 150 |
| 14 | 2iw | Crystal structure of Tankyrase 1 with IWR2 | 4dvi | 192 |
| 15 | k4f | Co-crystal structure of TNKS1 with compound 18 [4-[(4S)-5,5-dimethyl-2-oxo-4-phenyl-1,3-oxazolidin-3-yl]-N-(quinolin-8-yl)benzamide] | 4k4f | 200 |
| 16 | 1sx | Tankyrase-1 complexed with small molecule inhibitor | 4krs | 299 |
| 17 | 1xp | TANKYRASE-1 complexed with small molecule inhibitor 4-chloro-5-cyano-N-{2-[4-(4-fluorobenzoyl)piperidin-1-yl]ethyl}-2-methoxybenzamide | 4li7 | 770 |