| Index | Ligand Name | Structure | PDB code | Compound Potency nM |
| 1 | 59b | Tankyrase 2 complexed with a selective inhibitor | 5dcz | 0.5 |
| 2 | sgw | Crystal structure of human tankyrase 2 in complex with 3-(4- chlorophenyl)-5-methoxy-1,2- dihydroisoquinolin-1-one | 4uvy | 5.5 |
| 3 | a64 | Crystal structure of human tankyrase 2 in complex with 4'-isopropylflavone | 4bs4 | 6 |
| 4 | 92t | Crystal structure of human tankyrase 2 in complex with OD336 | 5nob | 6.3 |
| 5 | m3w | Crystal structure of human tankyrase 2 in complex with TA-13 | 4ufy | 7 |
| 6 | 2zi | Crystal structure of human tankyrase 2 in complex with TA-12 | 4ufu | 10 |
| 7 | h2w | Crystal structure of human tankyrase 2 in complex with 3-(4- chlorophenyl)-5-fluoro-1,2-dihydroisoquinolin-1-one | 4uvx | 11 |
| 8 | rpb | Crystal structure of human tankyrase 2 in complex with Rucaparib | 4bjc | 14 |
| 9 | aj5 | Tankyrase 2 in complex with 3-chloro-N-(2-methoxyethyl)-4-(4-methyl-2-oxo-1,2-dihydroquinolin-7-yl)benzamide | 4j3l | 16 |
| 10 | aj7 | Tankyrase 2 in complex with 3-chloro-4-(4-methyl-2-oxo-1,2-dihydroquinolin-7-yl)-N-[2-(morpholin-4-yl)ethyl]benzamide | 4j22 | 18 |
| 11 | w8l | Crystal structure of human tankyrase 2 in complex with 3-(4- chlorophenyl)-5-methyl-1,2-dihydroisoquinolin-1-one | 4uvv | 32 |
| 12 | 8ir | Crystal structure of human tankyrase 2 in complex with OD332 | 5aeh | 37 |
| 13 | iwr | Crystal structure of human tankyrase 2 in complex with a selective inhibitor | 3ua9 | 56 |
| 14 | jl9 | Crystal structure of TNKS2 in complex with 2-(4-((pyridin-4-yl)methyl) piperazin-1-yl)-3,4,5,6,7,8-hexahydroquinazolin-4-one | 5al5 | 71 |
| 15 | 09l | Crystal Structure of human Tankyrase 2 in complex with AZD2281. | 4tkg | 140 |
| 16 | 29f | Crystal structure of TNKS2 in complex with 2-(4-tert-butylphenyl)-1,2, 3,4-tetrahydroquinazolin-4-one | 5aku | 150 |
| 17 | 28c | Human tankyrase 2 - catalytic Parp domain in complex with an inhibitor UPF1854 | 4m7b | 200 |
| 18 | 33c | Crystal Structure of human Tankyrase 2 in complex with IWR-1. | 4tkf | 285 |
| 19 | wlh | Crystal structure of TNKS2 in complex with 2-(4-methylpiperazin-1-yl)- 3,4,5,6,7,8-hexahydroquinazolin-4-one | 5al4 | 300 |
| 20 | o53 | Crystal structure of TNKS2 in complex with 2-(4-(propan-2-yl)phenyl)- 1H,2H,3H,4H-pyrido(2,3-d)pyrimidin-4-one | 5al2 | 360 |
| 21 | 3gn | Crystal Structure of human Tankyrase 2 in complex with ABT-888. | 4tjy | 367 |
| 22 | nki | Crystal structure of TNKS2 in complex with 2-(4-chlorophenyl)-1,2,3,4- tetrahydroquinazolin-4-one | 5akw | 410 |
| 23 | sz5 | Crystal structure of human tankyrase 2 in complex with TA-21 | 4uhg | 540 |
| 24 | u1t | Crystal structure of human tankyrase 2 in complex with 1-((4-(5- methyl-1-oxo-1,2-dihydroisoquinolin-3-yl)phenyl)methyl)pyrrolidin-1- ium | 4uvu | 1200 |
| 25 | a95 | Crystal structure of human tankyrase 2 in complex with JW55 | 5adq | 2010 |
| 26 | qns | Crystal structure of human tankyrase 2 in complex with OD39 | 5ads | 2150 |
| 27 | 1tc | Crystal structure of human tankyrase 2 in complex with OD73 | 5adt | 2230 |
| 28 | qs5 | Crystal structure of human tankyrase 2 in complex with OD38 | 5adr | 2300 |
| 29 | 32z | Crystal Structure of human Tankyrase 2 in complex with DPQ. | 4tk0 | 2800 |
| 30 | cnq | Crystal Structure of human Tankyrase 2 in complex with 3,4-CPQ-5-C. | 4tju | 3600 |
| 31 | tgw | Crystal structure of TNKS2 in complex with 2-(2,4-dichlorophenyl)-1- methyl-1H,2H,3H,4H-pyrido(2,3-d)pyrimidin-4-one | 5al3 | 1.1e+004 |
| 32 | gn5 | Crystal structure of TNKS2 in complex with 2-(4-tert-butylphenyl)-1H, 2H,3H,4H-pyrido(2,3-d)pyrimidin-4-one | 5al1 | 5.3e+004 |