Index | Ligand Name | Structure | PDB code | Compound Potency nM |
1 | 16v | The Structure of V122I Mutant Transthyretin in Complex with AG10 | 4hiq | 6.2 |
2 | tcw | V122I Transthyretin structure in complex with Tolcalpone | 5a6i | 56 |
3 | 3m3 | Human transthyretin (TTR) complexed with 4-(3-(2-flourophenoxy)propyl)-3,5-dimethyl-1H-pyrazole | 3p3t | 57.91 |
4 | 1fl | Human transthyretin (ttr) complexed with diflunisal | 3d2t | 75 |
5 | 6j3 | Crystal Structure of Human Transthyretin in Complex with Clonixin | 5l4i | 260 |
6 | 3m4 | Human transthyretin (TTR) complexed with 5-(2-ethoxyphenyl)-3-(pyridin-4-yl)-1,2,4-oxadiazole | 3p3u | 329.1 |
7 | 6b5 | Crystal structure of human transthyretin in complex with luteolin-MeO at 1.35 A resolution | 5ihh | 390 |
8 | xlo | Wild-type Transthyretin in complex with 3-[(1E)-2-(2-Chloro-4-hydroxyphenyl)ethenyl]benzoic Acid | 5u4d | 470 |
9 | agi | Crystal Structure of the Wild Type TTR Binding Apigenin (TTRwt:API) | 4der | 490 |
10 | ft2 | CRYSTAL STRUCTURE OF TRANSTHYRETIN IN COMPLEX WITH LIGAND C-3 | 4abv | 850 |
11 | g24 | V30M mutant human transthyretin (TTR) complexed with GC-24 (V30M:GC-24) | 3nex | 1000 |
12 | g24 | Wild type human transthyretin (TTR) complexed with GC-24 (TTRwt:GC-24) | 3neo | 1200 |
13 | gen | Wild type human transthyretin (TTR) complexed with genistein (TTRwt:GEN) pH 7.5 | 3kgu | 1200 |
14 | 57d | Crystal Structure of the Wild Type TTR Binding Chrysin (TTRwt:CHR) | 4des | 1400 |
15 | a93 | Transthyretin in complex with a covalent small molecule kinetic stabilizer | 3hj0 | 1960 |
16 | kmp | Crystal Structure of the Wild Type TTR Binding Kaempferol (TTRwt:KAE) | 4det | 2100 |
17 | b72 | V30M mutant human transthyretin (TTR) complexed with GC-1 (V30M:GC-1) | 3nes | 2400 |
18 | gen | V30M mutant human transthyretin (TTR) complexed with genistein (V30M:GEN) pH 7.5 | 3kgt | 3100 |
19 | ifa | Crystal structure of transthyretin in complex with iododiflunisal-betaAlaOMe | 3fc8 | 4100 |
20 | b72 | Wild type human transthyretin (TTR) complexed with GC-1 (TTRwt:GC-1) | 3nee | 4600 |
21 | ifb | Crystal structure of transthyretin in complex with iododiflunisal-betaAlaOH | 3fcb | 4900 |