| Index | Ligand Name | Structure | PDB code | Compound Potency nM |
|---|---|---|---|---|
| 1 | 3xv | Crystal structure of PRMT5:MEP50 with EPZ015666 and SAM | 4x61 | 1 |
| 2 | 3xv | Crystal structure of PRMT5:MEP50 with EPZ015666 and sinefungin | 4x60 | 1 |
| 3 | 5qh | Crystal structure of PRMT5:MEP50 with Compound 9 and sinefungin | 5emk | 13 |
| 4 | 5ql | Crystal structure of PRMT5:MEP50 with Compound 15 and sinefungin | 5emm | 18 |
| 5 | 5qk | Crystal structure of PRMT5:MEP50 with Compound 10 and SAM | 5eml | 23 |
| 6 | 5qj | Crystal structure of PRMT5:MEP50 with Compound 8 and sinefungin | 5emj | 33 |