The Ligandable Human Proteome

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Sirtuin family

IndexLigand NameLigand StructureGene Name PrimaryProtein NameUniprot IDGene Name SynonymPDB Codes
14i5SIR1,SIR2NAD-dependent protein deacetylase sirtuin-2Q8IXJ6SIR2L SIR2L24i5i, 5d7q
21nsSIR1,SIR3NAD-dependent protein deacetylase sirtuin-3, mitochondrialQ9NTG7SIR2L34jt9, 4zzi
3l5cSIR2NAD-dependent protein deacetylase sirtuin-2Q8IXJ6SIR2L SIR2L25yqo
4l55SIR2NAD-dependent protein deacetylase sirtuin-2Q8IXJ6SIR2L SIR2L25yqn
5a2xSIR2NAD-dependent protein deacetylase sirtuin-2Q8IXJ6SIR2L SIR2L25yqm
68k9SIR2NAD-dependent protein deacetylase sirtuin-2Q8IXJ6SIR2L SIR2L25y0z
77kjSIR2NAD-dependent protein deacetylase sirtuin-2Q8IXJ6SIR2L SIR2L25mat
85grSIR2NAD-dependent protein deacetylase sirtuin-2Q8IXJ6SIR2L SIR2L25dy5
95gnSIR2NAD-dependent protein deacetylase sirtuin-2Q8IXJ6SIR2L SIR2L25dy4
103teSIR2NAD-dependent protein deacetylase sirtuin-2Q8IXJ6SIR2L SIR2L24rmg, 4rmh
113tkSIR2NAD-dependent protein deacetylase sirtuin-2Q8IXJ6SIR2L SIR2L24rmi
128noSIR2NAD-dependent protein deacetylase sirtuin-2Q8IXJ6SIR2L SIR2L25y5n
13oczSIR2,SIR3NAD-dependent protein deacetylase sirtuin-2Q8IXJ6SIR2L SIR2L24bv3, 4bvb, 4bvh, 5d7p
141nqSIR3NAD-dependent protein deacetylase sirtuin-3, mitochondrialQ9NTG7SIR2L34jsr
151nrSIR3NAD-dependent protein deacetylase sirtuin-3, mitochondrialQ9NTG7SIR2L34jt8
167n2SIR6NAD-dependent protein deacetylase sirtuin-6Q8N6T7SIR2L65mgn
177m2SIR6NAD-dependent protein deacetylase sirtuin-6Q8N6T7SIR2L65mf6