The Ligandable Human Proteome

NADP-dependent oxidoreductase domain

Index	Ligand Name	Gene Name Primary	Protein Name	Uniprot ID	Gene Name Synonym	PDB Codes
1	uv8	AK1BA	Aldo-keto reductase family 1 member B10	O60218	AKR1B11	5m2f
2	mk4	AK1BA	Aldo-keto reductase family 1 member B10	O60218	AKR1B11	5lix
3	flf	AK1BA	Aldo-keto reductase family 1 member B10	O60218	AKR1B11	4i5x
4	8ql	AK1BA	Aldo-keto reductase family 1 member B10	O60218	AKR1B11	5y7n
5	suz	AK1BA,AK1C2,AK1C3,ALDR	Aldo-keto reductase family 1 member B1	P15121	ALDR1 ALR2	3r7m, 3rx3, 3u2c, 4jq2, 4wev
6	qap	AK1BA,AK1C3	Aldo-keto reductase family 1 member B10	O60218	AKR1B11	4gq0, 5hnt
7	fid	AK1BA,ALDR	Aldo-keto reductase family 1 member B1	P15121	ALDR1 ALR2	1ef3, 1pwm, 2agt, 2pd9, 2pdw, 2pdy, 2pev, 2pf8, 2pfh, 4gab
8	tol	AK1BA,ALDR	Aldo-keto reductase family 1 member B1	P15121	ALDR1 ALR2	1zua, 2fzb, 2fzd, 2pdl
9	388	AK1BA,ALDR	Aldo-keto reductase family 1 member B1	P15121	ALDR1 ALR2	2iki, 3m4h, 5liu
10	zst	AK1BA,ALDR	Aldo-keto reductase family 1 member B1	P15121	ALDR1 ALR2	2dux, 2duz, 2dv0, 2fz8, 2fz9, 2hv5, 2hvn, 2hvo, 2pd5, 2pdb, 2pdf, 2pdi, 2pdm, 2pdx, 3len, 3m0i, 3mb9, 4jii
11	w8x	AK1BA,ALDR	Aldo-keto reductase family 1 member B10	O60218	AKR1B11	4lau, 5lik
12	1wx	AK1BA,ALDR	Aldo-keto reductase family 1 member B10	O60218	AKR1B11	4lb4, 5liw
13	5p3	AK1C1	Aldo-keto reductase family 1 member C1	Q04828	DDH DDH1	3nty
14	str	AK1C1,AK1C2,AK1D1	Aldo-keto reductase family 1 member C1	Q04828	DDH DDH1	1mrq, 3cot, 4l1w, 4l1x
15	jms	AK1C1,AK1C3	Aldo-keto reductase family 1 member C1	Q04828	DDH DDH1	3r6i, 6ijx
16	9s0	AK1C1,AK1C3	Aldo-keto reductase family 1 member C1	Q04828	DDH DDH1	6a7a, 6a7b
17	gbm	AK1C1,AK1C3	Aldo-keto reductase family 1 member C1	Q04828	DDH DDH1	4yvp, 4yvv
18	iu5	AK1C2	Aldo-keto reductase family 1 member C2	P52895	DDH2	1ihi
19	5sd	AK1C2	Aldo-keto reductase family 1 member C2	P52895	DDH2	4xo6
20	aox	AK1C2	Aldo-keto reductase family 1 member C2	P52895	DDH2	4xo6
21	ffa	AK1C2	Aldo-keto reductase family 1 member C2	P52895	DDH2	2ipj
22	flp	AK1C2	Aldo-keto reductase family 1 member C2	P52895	DDH2	4jtq
23	ibp	AK1C2	Aldo-keto reductase family 1 member C2	P52895	DDH2	4jtr
24	imn	AK1C2,AK1C3	Aldo-keto reductase family 1 member C3	P42330	DDH1 HSD17B5 KIAA0119 PGFS	1s2a, 3ug8, 3ugr, 4jq4
25	id8	AK1C2,AK1C3	Aldo-keto reductase family 1 member C2	P52895	DDH2	3r43, 4jqa
26	nps	AK1C2,AK1C3	Aldo-keto reductase family 1 member C3	P42330	DDH1 HSD17B5 KIAA0119 PGFS	3r58, 4jq1
27	zom	AK1C2,AK1C3	Aldo-keto reductase family 1 member C3	P42330	DDH1 HSD17B5 KIAA0119 PGFS	3r8h, 4jq3
28	asd	AK1C2,AK1C3,AK1D1	Aldo-keto reductase family 1 member C3	P42330	DDH1 HSD17B5 KIAA0119 PGFS	1xf0, 3cas, 4xo7
29	tes	AK1C2,AK1D1	Aldo-keto reductase family 1 member C2	P52895	DDH2	1j96, 3bur, 3uzz
30	ffw	AK1C3	Aldo-keto reductase family 1 member C3	P42330	DDH1 HSD17B5 KIAA0119 PGFS	6gxk
31	pg2	AK1C3	Aldo-keto reductase family 1 member C3	P42330	DDH1 HSD17B5 KIAA0119 PGFS	1ry0
32	e04	AK1C3	Aldo-keto reductase family 1 member C3	P42330	DDH1 HSD17B5 KIAA0119 PGFS	1zq5
33	15m	AK1C3	Aldo-keto reductase family 1 member C3	P42330	DDH1 HSD17B5 KIAA0119 PGFS	2f38
34	izp	AK1C3	Aldo-keto reductase family 1 member C3	P42330	DDH1 HSD17B5 KIAA0119 PGFS	3r8g
35	flr	AK1C3	Aldo-keto reductase family 1 member C3	P42330	DDH1 HSD17B5 KIAA0119 PGFS	3r94
36	npx	AK1C3	Aldo-keto reductase family 1 member C3	P42330	DDH1 HSD17B5 KIAA0119 PGFS	3ufy
37	511	AK1C3	Aldo-keto reductase family 1 member C3	P42330	DDH1 HSD17B5 KIAA0119 PGFS	4dbw
38	0t0	AK1C3	Aldo-keto reductase family 1 member C3	P42330	DDH1 HSD17B5 KIAA0119 PGFS	4fal
39	0sz	AK1C3	Aldo-keto reductase family 1 member C3	P42330	DDH1 HSD17B5 KIAA0119 PGFS	4fam
40	wdu	AK1C3	Aldo-keto reductase family 1 member C3	P42330	DDH1 HSD17B5 KIAA0119 PGFS	4wdu
41	wdx	AK1C3	Aldo-keto reductase family 1 member C3	P42330	DDH1 HSD17B5 KIAA0119 PGFS	4wdx
42	wdv	AK1C3	Aldo-keto reductase family 1 member C3	P42330	DDH1 HSD17B5 KIAA0119 PGFS	4xvd
43	wds	AK1C3	Aldo-keto reductase family 1 member C3	P42330	DDH1 HSD17B5 KIAA0119 PGFS	4xve
44	gmr	AK1C3	Aldo-keto reductase family 1 member C3	P42330	DDH1 HSD17B5 KIAA0119 PGFS	4yvx
45	gcz	AK1C3	Aldo-keto reductase family 1 member C3	P42330	DDH1 HSD17B5 KIAA0119 PGFS	4zfc
46	6ny	AK1C3	Aldo-keto reductase family 1 member C3	P42330	DDH1 HSD17B5 KIAA0119 PGFS	5jm5
47	cj2	AK1C3	Aldo-keto reductase family 1 member C3	P42330	DDH1 HSD17B5 KIAA0119 PGFS	6f2u
48	ci2	AK1D1	Aldo-keto reductase family 1 member D1	P51857	SRD5B1	3cav
49	bdt	AK1D1	Aldo-keto reductase family 1 member D1	P51857	SRD5B1	3uzy
50	pdn	AK1D1,KCAB2	Aldo-keto reductase family 1 member D1	P51857	SRD5B1	3cmf, 3eau, 3eb3, 3eb4
51	sfi	ALDR	Aldo-keto reductase family 1 member B1	P15121	ALDR1 ALR2	3rx4
52	lit	ALDR	Aldo-keto reductase family 1 member B1	P15121	ALDR1 ALR2	2ikh
53	itb	ALDR	Aldo-keto reductase family 1 member B1	P15121	ALDR1 ALR2	2nvd
54	ita	ALDR	Aldo-keto reductase family 1 member B1	P15121	ALDR1 ALR2	2nvc
55	3t4	ALDR	Aldo-keto reductase family 1 member B1	P15121	ALDR1 ALR2	3t42
56	i84	ALDR	Aldo-keto reductase family 1 member B1	P15121	ALDR1 ALR2	1el3
57	zes	ALDR	Aldo-keto reductase family 1 member B1	P15121	ALDR1 ALR2	1iei
58	bfi	ALDR	Aldo-keto reductase family 1 member B1	P15121	ALDR1 ALR2	1pwl
59	id5	ALDR	Aldo-keto reductase family 1 member B1	P15121	ALDR1 ALR2	1t40, 1t41
60	fir	ALDR	Aldo-keto reductase family 1 member B1	P15121	ALDR1 ALR2	1x97
61	3na	ALDR	Aldo-keto reductase family 1 member B1	P15121	ALDR1 ALR2	1z3n
62	393	ALDR	Aldo-keto reductase family 1 member B1	P15121	ALDR1 ALR2	2ikj, 2pdc, 2pdj, 2pdp, 2pdu, 2pzn, 3m64, 3mc5
63	q74	ALDR	Aldo-keto reductase family 1 member B1	P15121	ALDR1 ALR2	3g5e
64	ldt	ALDR	Aldo-keto reductase family 1 member B1	P15121	ALDR1 ALR2	1us0, 2i16, 2i17, 2pev, 2pf8, 2pfh, 2qxw, 2r24, 3ghr, 3ghs, 3ght, 3ghu, 3lbo, 3ld5, 3lql, 3lz5
65	doy	ALDR	Aldo-keto reductase family 1 member B1	P15121	ALDR1 ALR2	3p2v
66	slo	ALDR	Aldo-keto reductase family 1 member B1	P15121	ALDR1 ALR2	3rx2
67	tlt	ALDR	Aldo-keto reductase family 1 member B1	P15121	ALDR1 ALR2	3s3g
68	nti	ALDR	Aldo-keto reductase family 1 member B1	P15121	ALDR1 ALR2	3v35
69	2x9	ALDR	Aldo-keto reductase family 1 member B1	P15121	ALDR1 ALR2	4gca
70	1ww	ALDR	Aldo-keto reductase family 1 member B1	P15121	ALDR1 ALR2	4laz
71	m15	ALDR	Aldo-keto reductase family 1 member B1	P15121	ALDR1 ALR2	4lb3
72	4o9	ALDR	Aldo-keto reductase family 1 member B1	P15121	ALDR1 ALR2	4lbr
73	4o8	ALDR	Aldo-keto reductase family 1 member B1	P15121	ALDR1 ALR2	4lbs
74	2wr	ALDR	Aldo-keto reductase family 1 member B1	P15121	ALDR1 ALR2	4puu
75	2wq	ALDR	Aldo-keto reductase family 1 member B1	P15121	ALDR1 ALR2	4puw
76	2yz	ALDR	Aldo-keto reductase family 1 member B1	P15121	ALDR1 ALR2	4q7b
77	30l	ALDR	Aldo-keto reductase family 1 member B1	P15121	ALDR1 ALR2	4qbx
78	37v	ALDR	Aldo-keto reductase family 1 member B1	P15121	ALDR1 ALR2	4qr6
79	i98	ALDR	Aldo-keto reductase family 1 member B1	P15121	ALDR1 ALR2	4qxi
80	3uh	ALDR	Aldo-keto reductase family 1 member B1	P15121	ALDR1 ALR2	4rpq
81	4g7	ALDR	Aldo-keto reductase family 1 member B1	P15121	ALDR1 ALR2	4ys1
82	av5	ALDR	Aldo-keto reductase family 1 member B1	P15121	ALDR1 ALR2	5ou0
83	aw8	ALDR	Aldo-keto reductase family 1 member B1	P15121	ALDR1 ALR2	5ouj
84	avt	ALDR	Aldo-keto reductase family 1 member B1	P15121	ALDR1 ALR2	5ouk
85	wy1	ALDR	Aldo-keto reductase family 1 member B1	P15121	ALDR1 ALR2	5ha7
86	lpa	ALDR	Aldo-keto reductase family 1 member B1	P15121	ALDR1 ALR2	2iqd