Index | Gene Name Primary | Protein Name | Uniprot ID | Gene Name Synonym | Ligand Name | Structure | PDB Code | ligand desolvation | Ligand Structure | Compound Affinity nM |
1 | HEMH | Ferrochelatase, mitochondrial | P22830 | | chd | CRYSTAL STRUCTURE OF HUMAN FERROCHELATASE | 1hrk | 84.06 | | no data |
2 | HEMH | Ferrochelatase, mitochondrial | P22830 | | chd | F337R variant of human ferrochelatase | 4f4d | 84.95 | | no data |
3 | HEMH | Ferrochelatase, mitochondrial | P22830 | | chd | Crystal structure of human ferrochelatase mutant with His 341 replaced by Cys | 2po7 | 86.11 | | no data |
4 | HEMH | Ferrochelatase, mitochondrial | P22830 | | chd | Crystal structure of human ferrochelatase mutant with Phe 337 replaced by Ala | 2pnj | 84.7 | | no data |
5 | HEMH | Ferrochelatase, mitochondrial | P22830 | | chd | H240A variant of human ferrochelatase | 3aqi | 85.11 | | no data |
6 | HEMH | Ferrochelatase, mitochondrial | P22830 | | chd | Crystal structure of human ferrochelatase mutant with His 263 replaced by Cys | 2po5 | 82.21 | | no data |
7 | HEMH | Ferrochelatase, mitochondrial | P22830 | | chd | Protein-drug complex | 3w1w | 88.17 | | no data |
8 | HEMH | Ferrochelatase, mitochondrial | P22830 | | chd | Human ferrochelatase with Cd and protoporphyrin IX bound | 3hco | 36.47 | | no data |
9 | HEMH | Ferrochelatase, mitochondrial | P22830 | | chd | Hg and protoporphyrin bound Human Ferrochelatase | 3hcn | 85.96 | | no data |
10 | HEMH | Ferrochelatase, mitochondrial | P22830 | | chd | Human Ferrochelatase with deuteroporphyrin and Ni Bound | 3hcr | 82.49 | | no data |
11 | HEMH | Ferrochelatase, mitochondrial | P22830 | | chd | 1.7 angstrom structure of human ferrochelatase variant R115L | 2hrc | 85.22 | | no data |
12 | HEMH | Ferrochelatase, mitochondrial | P22830 | | chd | M76H variant of human ferrochelatase | 4kmm | 81.97 | | no data |
13 | HEMH | Ferrochelatase, mitochondrial | P22830 | | chd | F110A variant of human ferrochelatase with protoheme bound | 2qd2 | 83.9 | | no data |
14 | HEMH | Ferrochelatase, mitochondrial | P22830 | | chd | Wild type human ferrochelatase crystallized with ammonium sulfate | 2qd3 | 82.79 | | no data |
15 | HEMH | Ferrochelatase, mitochondrial | P22830 | | chd | Wild type human ferrochelatase crystallized with MnCl2 | 2qd4 | 85.5 | | no data |
16 | HEMH | Ferrochelatase, mitochondrial | P22830 | | chd | Structure of wild type human ferrochelatase in complex with a lead-porphyrin compound | 2qd5 | 79.64 | | no data |
17 | HEMH | Ferrochelatase, mitochondrial | P22830 | | chd | S197C variant of human ferrochelatase. | 4mk4 | 83.62 | | no data |
18 | HEMH | Ferrochelatase, mitochondrial | P22830 | | chd | E343D variant of human ferrochelatase | 4kla | 66.59 | | no data |
19 | HEMH | Ferrochelatase, mitochondrial | P22830 | | chd | E343Q variant of human ferrochelatase | 4klr | 85.75 | | no data |