The Ligandable Human Proteome


Adenylyl cyclase class-3/4/guanylyl cyclase

IndexGene Name PrimaryProtein NameUniprot IDGene Name SynonymLigand NameStructurePDB Codeligand desolvationLigand StructureCompound Affinity nM
1ADCYAAdenylate cyclase type 10Q96PN6SAC1veHuman solAC Complexed with (4-Aminofurazan-3-yl)-[3-(1H-benzoimidazol-2-ylmethoxy)phenyl]methanone4oya92.65360.
2ADCYAAdenylate cyclase type 10Q96PN6SAClriCrystal structure of the human soluble cyclase in complex with the allosteric inhibitor LRE15iv498.553300.
3ADCYAAdenylate cyclase type 10Q96PN6SAClriCrystal structure of human soluble adenylyl cyclase in complex with alpha,beta-methyleneadenosine-5'-triphosphate and the allosteric inhibitor LRE15iv3100no data