The Ligandable Human Proteome

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Peptidase C19, ubiquitin carboxyl-terminal hydrolase

IndexGene Name PrimaryProtein NameUniprot IDGene Name SynonymLigand NameStructurePDB Codeligand desolvationLigand StructureCompound Affinity nM
1UBP14Ubiquitin carboxyl-terminal hydrolase 14P54578TGTiu1USP14 catalytic domain with IU16iik81.59no data
2UBP14Ubiquitin carboxyl-terminal hydrolase 14P54578TGTa8oUSP14 catalytic domain with IU1-2486iin77.99no data
3UBP14Ubiquitin carboxyl-terminal hydrolase 14P54578TGTa8lUSP14 catalytic domain with IU1-2066iim80.67no data
4UBP14Ubiquitin carboxyl-terminal hydrolase 14P54578TGTa8fUSP14 catalytic domain bind to IU1-476iil81.04no data
5UBP15Ubiquitin carboxyl-terminal hydrolase 15Q9Y4E8KIAA0529mixUSP15 catalytic domain in complex with small molecule6gh936.51no data
6UBP7Ubiquitin carboxyl-terminal hydrolase 7Q93009HAUSP9qdStructure of DUB complex5vs668.85104.
7UBP7Ubiquitin carboxyl-terminal hydrolase 7Q93009HAUSP8wnCrystal structure of USP7 in complex with the covalent inhibitor, FT8275ngf77.667800.
8UBP7Ubiquitin carboxyl-terminal hydrolase 7Q93009HAUSP8wkCrystal structure of USP7 in complex with the non-covalent inhibitor, FT6715nge82.5865.
9UBP7Ubiquitin carboxyl-terminal hydrolase 7Q93009HAUSP8qqCrystal structure of USP7 in complex with a potent, selective and reversible small-molecule inhibitor5n9t84.43220.
10UBP7Ubiquitin carboxyl-terminal hydrolase 7Q93009HAUSP8rnCrystal structure of USP7 in complex with a potent, selective and reversible small-molecule inhibitor5n9r90.012600.
11UBP7Ubiquitin carboxyl-terminal hydrolase 7Q93009HAUSPcq5Crystal structure of USP7 in complex with a 4-hydroxypiperidine based inhibitor6f5h83.91no data
12UBP7Ubiquitin carboxyl-terminal hydrolase 7Q93009HAUSPajjUSP7 in complex with Cpd2 (4-(3-(1-methylpiperidin-4-yl)-1,2,4-oxadiazol-5-yl)phenol)5whc79.9512000.
13UBP7Ubiquitin carboxyl-terminal hydrolase 7Q93009HAUSP9qaStructure of DUB complex5vsb85.797614.
14UBP7Ubiquitin carboxyl-terminal hydrolase 7Q93009HAUSP8jpUSP7 in complex with GNE6776 (6'-amino-4'-ethyl-5'-(4-hydroxyphenyl)-N-methyl-[3,3'-bipyridine]-6-carboxamide)5uqx87.1610.
15UBP7Ubiquitin carboxyl-terminal hydrolase 7Q93009HAUSP8jmUSP7 in complex with GNE6640 (4-(2-amino-4-ethyl-5-(1H-indazol-5-yl)pyridin-3-yl)phenol)5uqv86.17430.