Index | Gene Name Primary | Protein Name | Uniprot ID | Gene Name Synonym | Ligand Name | Structure | PDB Code | ligand desolvation | Ligand Structure | Compound Affinity nM |
1 | ATS1 | A disintegrin and metalloproteinase with thrombospondin motifs 1 | Q9UHI8 | KIAA1346 METH1 | qhf | Adamts1 in complex with N-hydroxyformamide inhibitors of ADAM-TS4 | 3q2h | 77.04 | | 0.69 |
2 | ATS1 | A disintegrin and metalloproteinase with thrombospondin motifs 1 | Q9UHI8 | KIAA1346 METH1 | qgf | Adamts1 in complex with a novel N-hydroxyformamide inhibitors | 3q2g | 77.05 | | 3.5 |
3 | ATS4 | A disintegrin and metalloproteinase with thrombospondin motifs 4 | O75173 | KIAA0688 | 3pq | Crystal structure of human ADAMTS-4 in complex with inhibitor (compound 1, 2-(4-chlorophenoxy)-N-{[(4R)-4-methyl-2,5-dioxoimidazolidin-4-yl]methyl} acetamide) | 4wk7 | 87.42 | | 74. |
4 | ATS4 | A disintegrin and metalloproteinase with thrombospondin motifs 4 | O75173 | KIAA0688 | 3pu | Crystal structure of human ADAMTS-4 in complex with inhibitor 5-chloro-N-{[(4R)-2,5-dioxo-4-(1,3-thiazol-2-yl)imidazolidin-4-yl]methyl}-1-benzofuran-2-carboxamide (compound 10) | 4wke | 85.32 | | 8. |
5 | ATS4 | A disintegrin and metalloproteinase with thrombospondin motifs 4 | O75173 | KIAA0688 | 3pw | Crystal structure of human ADAMTS-4 in complex with inhibitor 5-CHLORO-N-{[(4S)-4-(1-METHYL-1H-IMIDAZOL-2-YL)-2,5-DIOXOIMIDAZOLIDIN-4-YL]METHYL}-1-BENZOFURAN-2-CARBOXAMIDE (compound 11) | 4wki | 80.28 | | 5. |
6 | ATS5 | A disintegrin and metalloproteinase with thrombospondin motifs 5 | Q9UNA0 | ADAMTS11 ADMP2 | 098 | Crystal Structure of the Catalytic Domain of ADAMTS-5 in Complex with an Amino-2-indanol compound | 3hy9 | 76.79 | | 17. |
7 | ATS5 | A disintegrin and metalloproteinase with thrombospondin motifs 5 | Q9UNA0 | ADAMTS11 ADMP2 | 099 | Crystal Structure of the Catalytic Domain of ADAMTS-5 in Complex with an Amino-2-indanol compound | 3hyg | 79.91 | | 93. |
8 | ATS5 | A disintegrin and metalloproteinase with thrombospondin motifs 5 | Q9UNA0 | ADAMTS11 ADMP2 | la3 | Crystal Structure of the Catalytic Domain of ADAMTS-5 in Complex with an Amino-2-indanol compound | 3ljt | 78.28 | | 129. |