The Ligandable Human Proteome

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Aminoacyl-tRNA synthetase, class II (G/ P/ S/T)

IndexGene Name PrimaryProtein NameUniprot IDGene Name SynonymLigand NameStructurePDB Codeligand desolvationLigand StructureCompound Affinity nM
1SYEPBifunctional glutamate/proline--tRNA ligaseP07814GLNS PARS QARS QPRSadnCrystal structure of human prolyl-tRNA synthetase (substrate bound form)4k8789.36no data
2SYEPBifunctional glutamate/proline--tRNA ligaseP07814GLNS PARS QARS QPRS91yCrystal structure of human Prolyl-tRNA synthetase (PRS) in complex with inhibitor5vad92.760.76
3SYEPBifunctional glutamate/proline--tRNA ligaseP07814GLNS PARS QARS QPRShfgCrystal structure of human prolyl-tRNA synthetase in complex with halofuginone and ATP analogue4hvc98.37no data
4SYEPBifunctional glutamate/proline--tRNA ligaseP07814GLNS PARS QARS QPRShfgCrystal structure of human prolyl-tRNA synthetase (halofuginone bound form)4k8888.1no data