The Ligandable Human Proteome

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Nitric oxide synthase, N-terminal

IndexGene Name PrimaryProtein NameUniprot IDGene Name SynonymLigand NameStructurePDB Codeligand desolvationLigand StructureCompound Affinity nM
1NOS1Nitric oxide synthase, brainP29475s71Structure of rat neuronal nitric oxide synthase heme domain in complex with (R)-6-(3-amino-2-(5-(2-(6-amino-4-methylpyridin-2-yl) ethyl)pyridin-3-yl)propyl)-4-methylpyridin-2-amine4ctw84.82no data
2NOS1Nitric oxide synthase, brainP29475s42Structure of rat neuronal nitric oxide synthase heme domain in complex with 6-(3-Amino-2-(3-(2-(6-amino-4-methylpyridin-2-yl)ethyl) phenyl)propyl)-4-methylpyridin-2-amine4ctu85.78no data
3NOS1Nitric oxide synthase, brainP29475q14Structure of neuronal nitric oxide synthase heme domain in complex with (S)-1,3-bis((2-amino-4-methylpyridin-6-yl)-methoxy)-butan-4-amine4k5f76.29no data
4NOS1Nitric oxide synthase, brainP29475kpjStructure of rat neuronal nitric oxide synthase heme domain in complex with (S)-6-(2,3-difluoro-5-(2-(1-methylpyrrolidin-2-yl)ethyl)phenethyl)-4-methylpyridin-2-amine6ngz81.26no data
5NOS1Nitric oxide synthase, brainP29475kpjStructure of human neuronal nitric oxide synthase R354A/G357D mutant heme domain in complex with (S)-6-(2,3-difluoro-5-(2-(1-methylpyrrolidin-2-yl)ethyl)phenethyl)-4-methylpyridin-2-amine6ngh78.36no data
6NOS1Nitric oxide synthase, brainP29475knvStructure of rat neuronal nitric oxide synthase heme domain in complex with (S)-6-(2,3-difluoro-5-(2-(1-methylazetidin-2-yl)ethyl)phenethyl)-4-methylpyridin-2-amine6nhd79.61no data
7NOS1Nitric oxide synthase, brainP29475knvStructure of human neuronal nitric oxide synthase R354A/G357D mutant heme domain in complex with (S)-6-(2,3-difluoro-5-(2-(1-methylazetidin-2-yl)ethyl)phenethyl)-4-methylpyridin-2-amine6nhc88.57no data
8NOS1Nitric oxide synthase, brainP29475knsStructure of human neuronal nitric oxide synthase R354A/G357D mutant heme domain in complex with 6-(5-(2-((2S,4R)-4-ethoxy-1-methylpyrrolidin-2-yl)ethyl)-2,3-difluorophenethyl)-4-methylpyridin-2-amine6nhb83.86no data
9NOS1Nitric oxide synthase, brainP29475knsStructure of rat neuronal nitric oxide synthase heme domain in complex with 6-(5-(2-((2S,4R)-4-ethoxy-1-methylpyrrolidin-2-yl)ethyl)-2,3-difluorophenethyl)-4-methylpyridin-2-amine6nhe75.49no data
10NOS1Nitric oxide synthase, brainP29475kndStructure of human neuronal nitric oxide synthase R354A/G357D mutant heme domain in complex with (S)-6-(2,3-difluoro-5-(2-(4-methylmorpholin-3-yl)ethyl)phenethyl)-4-methylpyridin-2-amine6ngi80.77no data
11NOS1Nitric oxide synthase, brainP29475kndStructure of rat neuronal nitric oxide synthase heme domain in complex with (S)-6-(2,3-difluoro-5-(2-(4-methylmorpholin-3-yl)ethyl)phenethyl)-4-methylpyridin-2-amine6nh079.58no data
12NOS1Nitric oxide synthase, brainP29475kn4Structure of human neuronal nitric oxide synthase R354A/G357D mutant heme domain in complex with (R)-6-(2,3-difluoro-5-(2-(1-methylpyrrolidin-2-yl)ethyl)phenethyl)-4-methylpyridin-2-amine6ngf81.4no data
13NOS1Nitric oxide synthase, brainP29475kn4Structure of rat neuronal nitric oxide synthase heme domain in complex with (R)-6-(2,3-difluoro-5-(2-(1-methylpyrrolidin-2-yl)ethyl)phenethyl)-4-methylpyridin-2-amine6ngy78.72no data
14NOS1Nitric oxide synthase, brainP29475kmvStructure of human neuronal nitric oxide synthase R354A/G357D mutant heme domain in complex with 6-(2,3-difluoro-5-(3-(methylamino)prop-1-yn-1-yl)phenethyl)-4-methylpyridin-2-amine6nge80.51no data
15NOS1Nitric oxide synthase, brainP29475kmvStructure of rat neuronal nitric oxide synthase heme domain in complex with 6-(2,3-difluoro-5-(3-(methylamino)prop-1-yn-1-yl)phenethyl)-4-methylpyridin-2-amine6ngx78.16no data
16NOS1Nitric oxide synthase, brainP29475kmsStructure of rat neuronal nitric oxide synthase heme domain in complex with 6-(5-(3-(dimethylamino)propyl)-2,3,4-trifluorophenethyl)-4-methylpyridin-2-amine6ngw77.45no data
17NOS1Nitric oxide synthase, brainP29475kmsStructure of human neuronal nitric oxide synthase R354A/G357D mutant heme domain in complex with 6-(5-(3-(dimethylamino)propyl)-2,3,4-trifluorophenethyl)-4-methylpyridin-2-amine6ngd84.77no data
18NOS1Nitric oxide synthase, brainP29475kmmStructure of human neuronal nitric oxide synthase R354A/G357D mutant heme domain in complex with 6-(3-(3-(dimethylamino)propyl)-2,5,6-trifluorophenethyl)-4-methylpyridin-2-amine6ngc85.42no data
19NOS1Nitric oxide synthase, brainP29475kmmStructure of rat neuronal nitric oxide synthase heme domain in complex with 6-(3-(3-(dimethylamino)propyl)-2,5,6-trifluorophenethyl)-4-methylpyridin-2-amine6ngv82.74no data
20NOS1Nitric oxide synthase, brainP29475kmjStructure of human neuronal nitric oxide synthase R354A/G357D mutant heme domain in complex with 6-(3-(3-(dimethylamino)propyl)-2,5-difluorophenethyl)-4-methylpyridin-2-amine6ngb83.83no data
21NOS1Nitric oxide synthase, brainP29475kmjStructure of rat neuronal nitric oxide synthase heme domain in complex with 6-(3-(3-(dimethylamino)propyl)-2,5-difluorophenethyl)-4-methylpyridin-2-amine6ngu82.97no data
22NOS1Nitric oxide synthase, brainP29475kmdStructure of human neuronal nitric oxide synthase R354A/G357D mutant heme domain in complex with (R)-6-(3-fluoro-5-(2-(1-methylpyrrolidin-2-yl)ethyl)phenethyl)-4-methylpyridin-2-amine6ng581.5no data
23NOS1Nitric oxide synthase, brainP29475kmdStructure of rat neuronal nitric oxide synthase heme domain in complex with (R)-6-(3-fluoro-5-(2-(1-methylpyrrolidin-2-yl)ethyl)phenethyl)-4-methylpyridin-2-amine6ngm78.56no data
24NOS1Nitric oxide synthase, brainP29475kmaStructure of rat neuronal nitric oxide synthase heme domain in complex with (R)-6-(3-fluoro-5-(2-(pyrrolidin-2-yl)ethyl)phenethyl)-4-methylpyridin-2-amine6ngl83.27no data
25NOS1Nitric oxide synthase, brainP29475kmaStructure of human neuronal nitric oxide synthase R354A/G357D mutant heme domain in complex with (R)-6-(3-fluoro-5-(2-(pyrrolidin-2-yl)ethyl)phenethyl)-4-methylpyridin-2-amine6ng480.52no data
26NOS1Nitric oxide synthase, brainP29475km7Structure of human neuronal nitric oxide synthase R354A/G357D mutant heme domain in complex with 6-(3-(3-(dimethylamino)prop-1-yn-1-yl)-5-fluorophenethyl)-4-methylpyridin-2-amine6ng280.34no data
27NOS1Nitric oxide synthase, brainP29475km7Structure of rat neuronal nitric oxide synthase heme domain in complex with 6-(3-(3-(dimethylamino)prop-1-yn-1-yl)-5-fluorophenethyl)-4-methylpyridin-2-amine6ngk84.1no data
28NOS1Nitric oxide synthase, brainP29475kldStructure of human neuronal nitric oxide synthase R354A/G357D mutant heme domain in complex with 6-(3-fluoro-5-(2-((2R,4S)-4-fluoro-1-methylpyrrolidin-2-yl)ethyl)phenethyl)-4-methylpyridin-2-amine6ng790.56no data
29NOS1Nitric oxide synthase, brainP29475kldStructure of rat neuronal nitric oxide synthase heme domain in complex with 6-(3-fluoro-5-(2-((2R,4S)-4-fluoro-1-methylpyrrolidin-2-yl)ethyl)phenethyl)-4-methylpyridin-2-amine6ngr79.89no data
30NOS1Nitric oxide synthase, brainP29475klaStructure of rat neuronal nitric oxide synthase heme domain in complex with 6-(3-fluoro-5-(2-((2R,4S)-4-fluoropyrrolidin-2-yl)ethyl)phenethyl)-4-methylpyridin-2-amine6ngq78.86no data
31NOS1Nitric oxide synthase, brainP29475kl7Structure of human neuronal nitric oxide synthase R354A/G357D mutant heme domain in complex with 6-(3-(3-(dimethylamino)propyl)-2,6-difluorophenethyl)-4-methylpyridin-2-amine6nga86.31no data
32NOS1Nitric oxide synthase, brainP29475kl7Structure of rat neuronal nitric oxide synthase heme domain in complex with 6-(3-(3-(dimethylamino)propyl)-2,6-difluorophenethyl)-4-methylpyridin-2-amine6ngt82.47no data
33NOS1Nitric oxide synthase, brainP29475kl4Structure of rat neuronal nitric oxide synthase heme domain in complex with (S)-6-(3-fluoro-5-(2-(pyrrolidin-2-yl)ethyl)phenethyl)-4-methylpyridin-2-amine6ngn77.5no data
34NOS1Nitric oxide synthase, brainP29475kl4Structure of human neuronal nitric oxide synthase R354A/G357D mutant heme domain in complex with (S)-6-(3-fluoro-5-(2-(pyrrolidin-2-yl)ethyl)phenethyl)-4-methylpyridin-2-amine6ng690.05no data
35NOS1Nitric oxide synthase, brainP29475kl1Structure of human neuronal nitric oxide synthase R354A/G357D mutant heme domain in complex with 6-(5-(3-(dimethylamino)propyl)-2,3-difluorophenethyl)-4-methylpyridin-2-amine6ng881.79no data
36NOS1Nitric oxide synthase, brainP29475kl1Structure of rat neuronal nitric oxide synthase heme domain in complex with 6-(5-(3-(dimethylamino)propyl)-2,3-difluorophenethyl)-4-methylpyridin-2-amine6ngs80.72no data
37NOS1Nitric oxide synthase, brainP29475kkyStructure of rat neuronal nitric oxide synthase heme domain in complex with (S)-6-(3-fluoro-5-(2-(1-methylpyrrolidin-2-yl)ethyl)phenethyl)-4-methylpyridin-2-amine6ngp80.1no data
38NOS1Nitric oxide synthase, brainP29475ji2Structure of neuronal NOS D597N/M336V mutant heme domain in complex with a inhibitor (+-)-N1-{cis-4'-[(6""-aminopyridin-2""-yl)methyl]pyrrolidin-3'-yl}ethane-1,2-diamine3dqr79.62no data
39NOS1Nitric oxide synthase, brainP29475ji2Structure of neuronal NOS heme domain in complex with a inhibitor (+-)-N1-{cis-4'-[(6""-aminopyridin-2""-yl)methyl]pyrrolidin-3'-yl}ethane-1,2-diamine3b3n84.69no data
40NOS1Nitric oxide synthase, brainP29475hw6Structure of rat nitric oxide synthase heme domain in complex with 6-(((3R,4R)-4-((5-(3-chloro-5-fluorophenyl)pentyl)oxy)pyrrolidin-3-yl)methyl)-4-methylpyridin-2-amine3ufs83.8no data
41NOS1Nitric oxide synthase, brainP29475f2jStructure of human neuronal nitric oxide synthase R354A/G357D mutant heme domain in complex with N-(1-(Piperidin-4-yl)indolin-5-yl)thiophene-2-carboximidamide6cid84.26no data
42NOS1Nitric oxide synthase, brainP29475by7Structure of human neuronal nitric oxide synthase R354A/G357D mutant heme domain in complex with 6-(3-(3-(dimethylamino)propyl)-5-(trifluoromethyl)phenethyl)-4-methylpyridin-2-amine6av279.78no data
43NOS1Nitric oxide synthase, brainP29475by7Structure of rat neuronal nitric oxide synthase heme domain in complex with 6-(3-(3-(dimethylamino)propyl)-5-(trifluoromethyl)phenethyl)-4-methylpyridin-2-amine6auu86.67no data
44NOS1Nitric oxide synthase, brainP294757s7Structure of rat neuronal nitric oxide synthase heme domain in complex with 6-(3-amino-2-(6-(2-(6-amino-4-methylpyridin-2-yl)ethyl) pyridin-2-yl)propyl)-4-methylpyridin-2-amine4ctv84.47no data
45NOS1Nitric oxide synthase, brainP294757r2Structure of the human nitric oxide synthase R354A/G357D mutant heme domain in complex with N-(1-(2-(Ethyl(methyl)amino)ethyl)-1,2,3,4-tetrahydroquino-lin-6-yl)thiophene-2-carboximidamide6cic81.53no data
46NOS1Nitric oxide synthase, brainP2947571sStructure of rat neuronal nitric oxide synthase heme domain in complex with (S)-6-(3-amino-2-(5-(2-(6-amino-4-methylpyridin-2-yl) ethyl)pyridin-3-yl)propyl)-4-methylpyridin-2-amine4ctx85.18no data
47NOS1Nitric oxide synthase, brainP29475arrNeuronal nitric oxide synthase oxygenase domain complexed with the inhibitor AR-R174771vag80.87no data
48NOS1Nitric oxide synthase, brainP29475j14Structure of rat neuronal nitric oxide synthase D597N/M336V mutant heme domain in complex with N1-{(3'S,4'R)-4'-[(6""-amino-4""-methylpyridin-2""-yl)methyl]pyrrolidin-3'-yl}-N2-(3'-fluorophenethyl)ethane-1,2-diamine3jx578.1no data
49NOS1Nitric oxide synthase, brainP29475j14Structure of rat neuronal nitric oxide synthase R349A mutant heme domain in complex with N1-{(3'S,4'R)-4'-[(6""-amino-4""-methylpyridin-2""-yl)methyl]pyrrolidin-3'-yl}-N2-(3'-fluorophenethyl)ethane-1,2-diamine3jwv78.4no data
50NOS1Nitric oxide synthase, brainP29475xjhStructure of neuronal nitric oxide synthase heme domain in complex with 6-(((3R,4R/3S,4S)-4-(3-Phenoxyphenoxy)pyrrolidin-3-yl)methyl)pyridin-2-amine3n2r77.36no data
51NOS1Nitric oxide synthase, brainP294753xbStructure of rat neuronal nitric oxide synthase heme domain in complex with 6-(((3R,4R)-4-(2- (2,2-Difluoro-2-(3-fluorophenyl)ethylamino)ethoxy)pyrrolidin-3-yl)methyl)-4-methylpyridin-2-amine3nlx86.8no data
52NOS1Nitric oxide synthase, brainP294753xdStructure of rat neuronal nitric oxide synthase heme domain in complex with 6-(((3R,4R)-4-(2-(2,2-Difluoro-2-phenylethylamino)ethoxy)pyrrolidin-3-yl)methyl)-4-methylpyridin-2-amine3nlz86.39no data
53NOS1Nitric oxide synthase, brainP294753xeStructure of rat neuronal nitric oxide synthase heme domain in complex with 6-(((3R,4R)-4-(2-(2,2-Difluoro-2-phenylethylamino)ethoxy) pyrrolidin-3-yl)methyl)-4-methyl-3,4,5,6-tetrahydropyridin-2-amine3nm086.52no data
54NOS1Nitric oxide synthase, brainP2947559rStructure of rat neuronal nitric oxide synthase heme domain complexed with 6-(((3R,4R)-4-(2-(3-Fluorophenethylamino)ethoxy)pyrrolidin-3-yl)methyl)pyridin-2-amine3nny82.58no data
55NOS1Nitric oxide synthase, brainP294758axStructure of rat neuronal nitric oxide synthase heme domain in complex with 6-(((3R,4R)-4-(2-((2,2-Difluoro-2-(3-chlorophenyl)ethyl)amino)ethoxy)pyrrolidin-3-yl)methyl)-4-methylpyridin-2-amine3pne87.33no data
56NOS1Nitric oxide synthase, brainP29475y2bStructure of the neuronal nitric oxide synthase heme domain in complex with 6-(((3R,4R)-4-(2-((1S,2R)-2-(3-Fluorophenyl)cyclopropylamino)ethoxy)pyrrolidin-3-yl)methyl)-4-methylpyridin-2-amine3rqj86.14no data
57NOS1Nitric oxide synthase, brainP29475x2cStructure of the neuronal nitric oxide synthase heme domain in complex with 4-methyl-6-{[(3R,4R)-4-(2-{[(1R,2S)-2-(3-methylphenyl)cyclopropyl]amino}ethoxy)pyrrolidin-3-yl]methyl}pyridin-2-amine and its isomer3rqk86.67no data
58NOS1Nitric oxide synthase, brainP29475x2dStructure of the neuronal nitric oxide synthase heme domain in complex with 6-(((3R,4R)-4-(2-((1S,2R/1R,2S)-2-(3-Clorophenyl)cyclopropylamino)ethoxy)pyrrolidin-3-yl)methyl)-4-methylpyridin-2-amine3rql87.84no data
59NOS1Nitric oxide synthase, brainP29475y2fStructure of the neuronal nitric oxide synthase heme domain in complex with 6-(((3*R*,4*R*)-4-(2-(((*S* )-1-(3-fluorophenyl)propan-2-yl)amino)ethoxy)pyrrolidin-3-yl)methyl)-4-methylpyridin-2-amine3rqn85.79no data
60NOS1Nitric oxide synthase, brainP29475x2eStructure of the neuronal nitric oxide synthase heme domain in complex with 6-{[(3R,4R)-4-(2-{[(2R/2S)-1-(3-fluorophenyl)propan-2-yl]amino}ethoxy)pyrrolidin-3-yl]methyl}-4-methylpyridin-2-amine3rqm85.86no data
61NOS1Nitric oxide synthase, brainP29475jk4Structure of rat neuronal nitric oxide synthase heme domain in complex with 6-(((3R,4R)-4-(2-((2,2-Difluoro-2-(2,3-difluorophenyl)ethyl)amino)ethoxy)pyrrolidin-3-yl)methyl)-4-methylpyridin-2-amine3svq84.12no data
62NOS1Nitric oxide synthase, brainP29475dxwStructure of neuronal nitric oxide synthase heme domain in complex with 6-(((3S,4S)-4-(2-((furan-2-ylmethyl)amino)ethoxy)pyrrolidin-3-yl)methyl)-4-methylpyridin-2-amine3tyo80.93no data
63NOS1Nitric oxide synthase, brainP29475hw4Structure of rat nitric oxide synthase heme domain in complex with 6-(((3S,4S)-4-((5-(3-fluorophenyl)pentyl)oxy)pyrrolidin-3-yl)methyl)-4-methylpyridin-2-amine3ufo76.16no data
64NOS1Nitric oxide synthase, brainP29475hw7Structure of rat nitric oxide synthase heme domain in complex with 6-(((3R,4R)-4-(4-(3-chloro-5-fluorophenoxy)butoxy)pyrrolidin-3-yl)methyl)-4-methylpyridin-2-amine3uft86.3no data
65NOS1Nitric oxide synthase, brainP29475m87Structure of rat neuronal nitric oxide synthase heme domain in complex with 7-((3-Fluorophenethylamino)methyl)quinolin-2-amine4cam77.39no data
66NOS1Nitric oxide synthase, brainP29475s20Structure of rat neuronal nitric oxide synthase heme domain in complex with 2-(6-Amino-4-methylpyridin-2-yl)-1-(3-(2-(6-amino-4- methylpyridin-2-yl)ethyl )phenyl)ethan-1-ol4ctr75.96no data
67NOS1Nitric oxide synthase, brainP29475hw0Structure of rat nitric oxide synthase heme domain in complex with 6-(((3R,4R)-4-((5-(6-aminopyridin-2-yl)pentyl)oxy)pyrrolidin-3-yl)methyl)-4-methylpyridin-2-amine3ufw84.81no data
68NOS1Nitric oxide synthase, brainP29475hw9Structure of rat nitric oxide synthase heme domain in complex with 4-methyl-6-(((3R,4R)-4-((5-(4-methylpyridin-2-yl)pentyl)oxy)pyrrolidin-3-yl)methyl)pyridin-2-amine3ufv83.45no data
69NOS1Nitric oxide synthase, brainP29475hw9Structure of rat neuronal nitric oxide synthase M336V D597N mutant heme domain in complex with 4-METHYL-6-(((3R,4R)-4-((5-(4- METHYLPYRIDIN-2-YL)PENTYL)OXY)PYRROLIDIN-3-YL)METHYL)PYRIDIN-2-AMINE4cx485.53no data
70NOS1Nitric oxide synthase, brainP29475hw8Structure of rat neuronal nitric oxide synthase M336V D597N mutant heme domain in complex with 4-METHYL-6-(((3R,4R)-4-((5-(PYRIDIN-2-YL) PENTYL)OXY)PYRROLIDIN-3-YL)METHYL)PYRIDIN-2-AMINE4cx385.2no data
71NOS1Nitric oxide synthase, brainP29475eg8Structure of human nNOS R354A G357D mutant heme domain in complex with N-2-(2-(1H-imidazol-1-yl)pyrimidin-4-yl)ethyl-3-(pyridin-3-yl) propan-1-amine4v3u77.68no data
72NOS1Nitric oxide synthase, brainP29475e2zStructure of rat neuronal nitric oxide synthase heme domain in complex with 2-(2-(1H-imidazol-1-yl)pyrimidin-4-yl)-N-(3- fluorophenethyl)ethan-1-amine4v3w72.21no data
73NOS1Nitric oxide synthase, brainP29475olwStructure of human nNOS R354A G357D mutant heme domain in complex with 3-(((2-((2-(1H-IMIDAZOL-1-YL)PYRIMIDIN-4-YL)ETHYL)AMINO)METHYL) BENZONITRILE4uch78.4no data
74NOS1Nitric oxide synthase, brainP29475olwStructure of rat neuronal nitric oxide synthase heme domain in complex with 2-(2-(1H-imidazol-1-yl)pyrimidin-4-yl)-N-(3-cyanobenzyl) ethan-1-amine4d3179.54no data
75NOS1Nitric oxide synthase, brainP29475q10Structure of rat neuronal nitric oxide synthase heme domain in complex with 6-((3-(3-aminopropoxy)phenoxy)methyl)-4-methylpyridin-2-amine4jsg82.01no data
76NOS1Nitric oxide synthase, brainP29475qj8Structure of rat neuronal nitric oxide synthase heme domain in complex with 6-((((3R,5S)-5-(((6-amino-4-methylpyridin-2-yl)methoxy)methyl)pyrrolidin-3-yl)oxy)methyl)-4-methylpyridin-2-amine4lux81.53no data
77NOS1Nitric oxide synthase, brainP29475hw1Structure of neuronal nitric oxide synthase heme domain in complex with 6-(5-(((3R,4R)-4-((6-amino-4-methylpyridin-2-yl)methyl)pyrrolidin-3-yl)oxy)pentyl)-4-methylpyridin-2-amine4eux84.58no data
78NOS1Nitric oxide synthase, brainP29475q16Structure of rat neuronal nitric oxide synthase heme domain in complex with 6-((((3S, 5R)-5-(((6-amino-4-methylpyridin-2-yl)methoxy) methyl)pyrrolidin-3-yl)oxy)methyl)-4-methylpyridin-2-amine4c3982.64no data
79NOS1Nitric oxide synthase, brainP29475q16Structure of rat neuronal nitric oxide synthase H341L mutant heme domain in complex with 6-((((3S, 5R)-5-(((6-AMINO-4-METHYLPYRIDIN-2- YL)METHOXY)METHYL)PYRROLIDIN-3-YL)OXY)METHYL)-4-METHYLPYRIDIN-2-AMINE4cx683.98no data
80NOS1Nitric oxide synthase, brainP294755h4Structure of neuronal nitric oxide synthase heme domain in complex with N-(3-((ethyl(3-fluorophenethyl)amino)methyl)phenyl)thiophene-2-carboximidamide4kco79.65no data
81NOS1Nitric oxide synthase, brainP294757m3Structure of rat neuronal nitric oxide synthase heme domain in complex with 7-((3-(Dimethylamino)methyl)phenoxy)methyl)quinolin-2- amine5ad676.54no data
82NOS1Nitric oxide synthase, brainP29475xebStructure of rat neuronal nitric oxide synthase heme domain in complex with 7-((4-Chloro-3-((methylamino)methyl)phenoxy)methyl) quinolin-2-amine5adb79.03no data
83NOS1Nitric oxide synthase, brainP29475xebStructure of human nNOS R354A G357D mutant heme domain in complex with 7-((4-Chloro-3-((methylamino)methyl)phenoxy)methyl)quinolin-2- amine5adg78.45no data
84NOS1Nitric oxide synthase, brainP29475xebStructure of rat neuronal nitric oxide synthase M336V D597N mutant heme domain in complex with 7-((4-Chloro-3-((methylamino)methyl) phenoxy)methyl)quinolin-2-amine5ade77.52no data
85NOS1Nitric oxide synthase, brainP29475d8hStructure of rat neuronal nitric oxide synthase heme domain in complex with 6-(2-(5-(3-methoxypropylamino)pyridin-3-yl)ethyl)-4- methylpyridin-2-amine5fvo74.81no data
86NOS1Nitric oxide synthase, brainP29475h65Structure of human nNOS R354A G357D mutant heme domain in complex with 4-methyl-6-(2-(5-(1-methylpiperidin-4-yl)pyridin-3-yl)ethyl) pyridin-2-amine5fvv82.98no data
87NOS1Nitric oxide synthase, brainP29475w66Structure of rat neuronal nitric oxide synthase heme domain in complex with 4-methyl-6-(2-(5-(3-(methylamino)propyl)pyridin-3-yl) ethyl)pyridin-2-amine5fvs83.69no data
88NOS1Nitric oxide synthase, brainP29475w64Structure of human nNOS R354A G357D mutant heme domain in complex with 4-methyl-6-(2-(5-(4-methylpiperazin-1-yl)pyridin-3-yl)ethyl) pyridin-2-amine5fvu84.93no data
89NOS1Nitric oxide synthase, brainP29475w67Structure of rat neuronal nitric oxide synthase M336V D597N mutant heme domain in complex with 6-(2-(5-(3-(DIMETHYLAMINO)PROPYL)PYRIDIN- 3-YL)ETHYL)-4-METHYLPYRIDIN-2-AMINE5g0p78.83no data
90NOS1Nitric oxide synthase, brainP29475m7kStructure of rat neuronal nitric oxide synthase heme domain in complex with 7-(2-(3-Fluorobenzylamino)ethyl)quinolin-2-amine4can79.39no data
91NOS1Nitric oxide synthase, brainP294752snStructure of rat neuronal nitric oxide synthase heme domain in complex with 7-(((3-((Dimethylamino)methyl)phenyl)amino)methyl) quinolin-2-amine5ada83.89no data
92NOS1Nitric oxide synthase, brainP29475m85Structure of rat neuronal nitric oxide synthase d597n m336v mutant heme domain in complex with 7-((3-(methylamino)methyl) phenoxy)methyl)quinolin-2-amine5add82.65no data
93NOS1Nitric oxide synthase, brainP294758j4Structure of rat neuronal nitric oxide synthase heme domain in complex with 7-[(3-Ethyl-5-((methylamino)methyl)phenoxy)methyl]quinolin-2-amine5uns76.73no data
94NOS1Nitric oxide synthase, brainP294758j4Structure of human neuronal nitric oxide synthase heme domain in complex with 7-[(3-Ethyl-5-((methylamino)methyl)phenoxy)methyl]quinolin-2-amine5uo278.7no data
95NOS1Nitric oxide synthase, brainP29475m4rStructure of human neuronal nitric oxide synthase heme domain in complex with (RS)-3-[(2-amino-4-methylquinolin-7-yl)methoxy]-5-(2-(methylamino)propyl)benzonitrile5uo586.69no data
96NOS1Nitric oxide synthase, brainP294759omStructure of human neuronal nitric oxide synthase heme domain in complex with 7-(((3-(4-Methylpyridin-3-yl)propyl)amino)methyl)quinolin-2-amine5vv074.28no data
97NOS1Nitric oxide synthase, brainP29475xh8Structure of rat neuronal nitric oxide synthase heme domain in complex with 7-(((3-(Pyridin-3-yl)propyl)amino)methyl)quinolin-2-amine5vum76.57no data
98NOS1Nitric oxide synthase, brainP29475xh8Structure of human neuronal nitric oxide synthase heme domain in complex with 7-(((3-(Pyridin-3-yl)propyl)amino)methyl)quinolin-2-amine5vuz76.27no data
99NOS1Nitric oxide synthase, brainP294759p4Structure of rat neuronal nitric oxide synthase heme domain in complex with 7-(((3-(5-Fluoropyridin-3-yl)propyl)amino)methyl)quinolin-2-amine5vup77.84no data
100NOS1Nitric oxide synthase, brainP294759p4Structure of human neuronal nitric oxide synthase heme domain in complex with 7-(((3-(5-Fluoropyridin-3-yl)propyl)amino)methyl)quinolin-2-amine5vv276.01no data
101NOS1Nitric oxide synthase, brainP29475w82Structure of human neuronal nitric oxide synthase R354A/G356D mutant heme domain in complex with 6-(2-(5-Fluoro-3'-((methylamino)methyl)-[1,1'-biphenyl]-3-yl)ethyl)-4-methylpyridin-2-amine6av583no data
102NOS1Nitric oxide synthase, brainP29475w80Structure of human neuronal nitric oxide synthase R354A/G357D mutant heme domain in complex with 4-Methyl-6-(2-(5-(4-((methylamino)methyl)phenyl)pyridin-3-yl)ethyl)pyridin-2-amine6av480.94no data
103NOS1Nitric oxide synthase, brainP29475w79Structure of human neuronal nitric oxide synthase R354A/G357D mutant heme domain in complex with 4-Methyl-6-(2-(5-(3-((methylamino)methyl)phenyl)pyridin-3-yl)ethyl)pyridin-2-amine6av386.19no data
104NOS1Nitric oxide synthase, brainP29475w69Structure of human neuronal nitric oxide synthase R354A/G357D mutant heme domain in complex with 6-(3-(3-(Dimethylamino)propyl)-5-fluorophenethyl)-4-methylpyridin-2-amine6av181.92no data
105NOS1Nitric oxide synthase, brainP29475byvStructure of human neuronal nitric oxide synthase R354A/G357D mutant heme domain in complex with 3-(2-(6-Amino-4-methylpyridin-2-yl)ethyl)-5-(3-(methylamino)propyl)benzonitrile6av081.38no data
106NOS1Nitric oxide synthase, brainP29475w68Structure of human neuronal nitric oxide synthase R354A/G357D mutant heme domain in complex with 6-(3-Fluoro-5-(3-(methylamino)propyl)phenethyl)-4-methylpyridin-2-amine6auz82.5no data
107NOS1Nitric oxide synthase, brainP29475byjStructure of human neuronal nitric oxide synthase R354A/G357D mutant heme domain in complex with 4-Methyl-6-(3-(3-(methylamino)propyl)phenethyl)pyridin-2-amine6auy84.77no data
108NOS1Nitric oxide synthase, brainP29475w82Structure of rat neuronal nitric oxide synthase heme domain in complex with 6-(2-(5-Fluoro-3'-((methylamino)methyl)-[1,1'-biphenyl]-3-yl)ethyl)-4-methylpyridin-2-amine6aux82.06no data
109NOS1Nitric oxide synthase, brainP29475w79Structure of rat neuronal nitric oxide synthase heme domain in complex with 4-Methyl-6-(2-(5-(3-((methylamino)methyl)phenyl)pyridin-3-yl)ethyl)pyridin-2-amine6auv83.52no data
110NOS1Nitric oxide synthase, brainP29475w69Structure of rat neuronal nitric oxide synthase heme domain in complex with 6-(3-(3-(Dimethylamino)propyl)-5-fluorophenethyl)-4-methylpyridin-2-amine6aut81.67no data
111NOS1Nitric oxide synthase, brainP29475byvStructure of rat neuronal nitric oxide synthase heme domain in complex with 3-(2-(6-Amino-4-methylpyridin-2-yl)ethyl)-5-(3-(methylamino)propyl)benzonitrile6aus81.37no data
112NOS1Nitric oxide synthase, brainP29475w68Structure of rat neuronal nitric oxide synthase heme domain in complex with 6-(3-Fluoro-5-(3-(methylamino)propyl)phenethyl)-4-methylpyridin-2-amine6aur83.31no data
113NOS1Nitric oxide synthase, brainP29475byjStructure of rat neuronal nitric oxide synthase heme domain in complex with 4-Methyl-6-(3-(3-(methylamino)propyl)phenethyl)pyridin-2-amine6auq85.55no data
114NOS1Nitric oxide synthase, brainP29475jhtStructure of human neuronal nitric oxide synthase heme domain in complex with 7-(((3-(Dimethylamino)benzyl)amino)methyl)quinolin-2-amine5vuw83.08no data
115NOS1Nitric oxide synthase, brainP29475jhtStructure of rat neuronal nitric oxide synthase heme domain in complex with 7-(((3-(Dimethylamino)benzyl)amino)methyl)quinolin-2-amine5vuj78.88no data
116NOS1Nitric oxide synthase, brainP294758fdStructure of human neuronal nitric oxide synthase heme domain in complex with (S)-3-[(2-amino-4-methylquinolin-7-yl)methoxy]-5-(2-(methylamino)propyl)benzonitrile5uo775.66no data
117NOS1Nitric oxide synthase, brainP29475m4rStructure of human neuronal nitric oxide synthase heme domain in complex with (R)-3-[(2-amino-4-methylquinolin-7-yl)methoxy]-5-(2-(methylamino)propyl)benzonitrile5uo674.73no data
118NOS1Nitric oxide synthase, brainP294758fdStructure of human neuronal nitric oxide synthase heme domain in complex with (RS)-3-[(2-amino-4-methylquinolin-7-yl)methoxy]-5-(2-(methylamino)propyl)benzonitrile5uo592.2no data
119NOS1Nitric oxide synthase, brainP294758f1Structure of human neuronal nitric oxide synthase heme domain in complex with 3-[(2-amino-4-methylquinolin-7-yl)methoxy]-5-(2-(methylamino)ethyl)benzonitrile5uo480.19no data
120NOS1Nitric oxide synthase, brainP294758eyStructure of human neuronal nitric oxide synthase heme domain in complex with 3-[(2-amino-4-methylquinolin-7-yl)methoxy]-5-((methylamino)methyl)benzonitrile5uo381.56no data
121NOS1Nitric oxide synthase, brainP294758fdStructure of rat neuronal nitric oxide synthase heme domain in complex with (S)-3-[(2-amino-4-methylquinolin-7-yl)methoxy]-5-(2-(methylamino)propyl)benzonitrile5uo080.2no data
122NOS1Nitric oxide synthase, brainP29475m4rStructure of rat neuronal nitric oxide synthase heme domain in complex with (R)-3-[(2-amino-4-methylquinolin-7-yl)methoxy]-5-(2-(methylamino)propyl)benzonitrile5unz79.88no data
123NOS1Nitric oxide synthase, brainP29475m4rStructure of rat neuronal nitric oxide synthase heme domain in complex with (RS)-3-[(2-amino-4-methylquinolin-7-yl)methoxy]-5-(2-(methylamino)propyl)benzonitrile5uny85.17no data
124NOS1Nitric oxide synthase, brainP294758fdStructure of rat neuronal nitric oxide synthase heme domain in complex with (RS)-3-[(2-amino-4-methylquinolin-7-yl)methoxy]-5-(2-(methylamino)propyl)benzonitrile5uny92.45no data
125NOS1Nitric oxide synthase, brainP294758f1Structure of rat neuronal nitric oxide synthase heme domain in complex with 3-[(2-amino-4-methylquinolin-7-yl)methoxy]-5-(2-(methylamino)ethyl)benzonitrile5unx82.95no data
126NOS1Nitric oxide synthase, brainP294758f7Structure of rat neuronal nitric oxide synthase heme domain in complex with 3-[2-(2-amino-4-methylquinolin-7-yl)ethyl]-5-((methylamino)methyl)benzonitrile5unw79.31no data
127NOS1Nitric oxide synthase, brainP294758j7Structure of rat neuronal nitric oxide synthase heme domain in complex with 4-Methyl-7-[3-((methylamino)methyl)phenethyl]quinolin-2-amine5unv82.46no data
128NOS1Nitric oxide synthase, brainP294758eyStructure of rat neuronal nitric oxide synthase heme domain in complex with 3-[(2-amino-4-methylquinolin-7-yl)methoxy]-5-((methylamino)methyl)benzonitrile5unu80.26no data
129NOS1Nitric oxide synthase, brainP294758j1Structure of rat neuronal nitric oxide synthase heme domain in complex with 4-Methyl-7-[(3-((methylamino)methyl)phenoxy)methyl]quinolin-2-amine5unt79.69no data
130NOS1Nitric oxide synthase, brainP29475w64Structure of rat neuronal nitric oxide synthase D597N mutant heme domain in complex with 4-METHYL-6-(2-(5-(4-METHYLPIPERAZIN-1-YL) PYRIDIN-3-YL)ETHYL)PYRIDIN-2-AMINE5g0o82.47no data
131NOS1Nitric oxide synthase, brainP29475exiStructure of rat neuronal nitric oxide synthase D597N mutant heme domain in complex with N1-(5-(2-(6-AMINO-4-METHYLPYRIDIN-2-YL)ETHYL) PYRIDIN-3-YL)-N1,N2-DIMETHYLETHANE-1,2-DIAMINE5g0n80.43no data
132NOS1Nitric oxide synthase, brainP29475w30Structure of rat neuronal nitric oxide synthase heme domain in complex with 6-(2-(5-((2-methoxyethyl)(methyl)amino)pyridin-3-yl) ethyl)-4-methylpyridin-2-amine5fw086.01no data
133NOS1Nitric oxide synthase, brainP29475w67Structure of human nNOS R354A G357D mutant heme domain in complex with with 6-(2-(5-(3-(DIMETHYLAMINO)PROPYL) PYRIDIN-3-YL)ETHYL)-4-METHYLPYRIDIN-2-AMINE5fvx82.34no data
134NOS1Nitric oxide synthase, brainP29475w66Structure of human nNOS R354A G357D mutant heme domain in complex with 4-methyl-6-(2-(5-(3-(methylamino)propyl)pyridin-3-yl)ethyl) pyridin-2-amine5fvw83.63no data
135NOS1Nitric oxide synthase, brainP29475w67Structure of rat neuronal nitric oxide synthase heme domain in complex with 6-(2-(5-(3-(dimethylamino)propyl)pyridin-3-yl)ethyl)-4- methylpyridin-2-amine5fvt83.55no data
136NOS1Nitric oxide synthase, brainP29475h65Structure of rat neuronal nitric oxide synthase heme domain in complex with 4-METHYL-6-(2-(5-(1-METHYLPIPERIDIN-4-YL)PYRIDIN-3-YL) ETHYL)PYRIDIN-2-AMINE5fvr83.53no data
137NOS1Nitric oxide synthase, brainP29475w64Structure of rat neuronal nitric oxide synthase heme domain in complex with 4-methyl-6-(2-(5-(4-methylpiperazin-1-yl)pyridin-3-yl) ethyl)pyridin-2-amine5fvq82.8no data
138NOS1Nitric oxide synthase, brainP29475wosStructure of rat neuronal nitric oxide synthase heme domain in complex with 4-methyl-6-[2-(5-morpholin-4-ylpyridin-3-yl)ethyl]pyridin-2-amine5fvp85.13no data
139NOS1Nitric oxide synthase, brainP294752snStructure of human nNOS R354A G357D mutant heme domain in complex with 7-(((3-((Dimethylamino)methyl)phenyl)amino)methyl)quinolin-2- amine5adf84.45no data
140NOS1Nitric oxide synthase, brainP294758vjStructure of rat neuronal nitric oxide synthase heme domain in complex with 7-((4-(Dimethylamino)methyl)phenoxy)methyl)quinolin-2- amine5ad977.91no data
141NOS1Nitric oxide synthase, brainP29475m85Structure of rat neuronal nitric oxide synthase heme domain in complex with 7-((3-(Methylamino)methyl)phenoxy)methyl)quinolin-2- amine5ad778.66no data
142NOS1Nitric oxide synthase, brainP29475m94Structure of rat neuronal nitric oxide synthase heme domain in complex with 7-((3-(2-(Methylamino)ethyl)phenoxy)methyl)quinolin-2- amine5ad581.64no data
143NOS1Nitric oxide synthase, brainP29475q1tStructure of human nNOS R354A G357D mutant heme domain in complex with 3-(2-(6-Amino-4-methylpyridin-2-yl)ethyl)-5-(methyl(2-(methylamino)ethyl)amino)benzonitrile4uh688.41no data
144NOS1Nitric oxide synthase, brainP29475exiStructure of human nNOS R354A G357D mutant heme domain in complex with N1-(5-(2-(6-Amino-4-methylpyridin-2-yl)ethyl)pyridin-3-yl)-N1,N2- dimethylethane-1,2-diamine4uh588.12no data
145NOS1Nitric oxide synthase, brainP29475q1tStructure of rat neuronal nitric oxide synthase heme domain in complex with 3-(2-(6-Amino-4-methylpyridin-2-yl)ethyl)-5-(methyl(2-(methylamino)ethyl)amino)benzonitrile4uh488.56no data
146NOS1Nitric oxide synthase, brainP29475s85Structure of rat neuronal nitric oxide synthase heme domain in complex with N1-(3-(2-(6-Amino-4-methylpyridin-2-yl)ethyl)-5- fluorophenyl)-N1,N2-dimethylethane-1,2-diamine4uh383.98no data
147NOS1Nitric oxide synthase, brainP29475s84Structure of rat neuronal nitric oxide synthase heme domain in complex with N1-(3-(2-(6-Amino-4-methylpyridin-2-yl)ethyl)-5-(trifluoromethyl)phenyl)-N1,N2-dimethylethane-1,2-diamine4uh288.82no data
148NOS1Nitric oxide synthase, brainP29475exiStructure of rat neuronal nitric oxide synthase heme domain in complex with N1-(5-(2-(6-Amino-4-methylpyridin-2-yl)ethyl)pyridin-3- yl)-N1,N2-dimethylethane-1,2-diamine4uh181.24no data
149NOS1Nitric oxide synthase, brainP29475skoStructure of rat neuronal nitric oxide synthase heme domain in complex with N1-(6-(2-(6-Amino-4-methylpyridin-2-yl)ethyl)pyridin-2- yl)-N1,N2-dimethylethane-1,2-diamine4uh087.65no data
150NOS1Nitric oxide synthase, brainP294754v4Structure of rat neuronal nitric oxide synthase heme domain in complex with N1-(3-(2-(6-Amino-4-methylpyridin-2-yl)ethyl)phenyl)-N1, N2-dimethylethane-1,2-diamine4ugz85.77no data
151NOS1Nitric oxide synthase, brainP294755h3Structure of neuronal nitric oxide synthase heme domain in complex with N-(3-(((3-fluorophenethyl)amino)methyl)phenyl)thiophene-2-carboximidamide4kcn84.31no data
152NOS1Nitric oxide synthase, brainP29475q15Structure of rat neuronal nitric oxide synthase heme domain in complex with 4-methyl-6-((3-(piperidin-4-ylmethoxy)phenoxy)methyl)pyridin-2-amine4jsh79.51no data
153NOS1Nitric oxide synthase, brainP29475cxwStructure of neuronal nitric oxide synthase heme domain in complex with 2-(((2-(((3S,4S)-4-((6-amino-4-methylpyridin-2-yl)methyl)pyrrolidin-3-yl)oxy)ethyl)amino)methyl)phenol3tyn78.2no data
154NOS1Nitric oxide synthase, brainP2947508rStructure of neuronal nitric oxide synthase heme domain in complex with 6-(((3S,4S)-4-(2-((2-methoxybenzyl)amino)ethoxy)pyrrolidin-3-yl)methyl)-4-methylpyridin-2-amine3tym76.01no data
155NOS1Nitric oxide synthase, brainP29475axwStructure of neuronal nitric oxide synthase heme domain in complex with 6-(((3S,4S)-4-(2-((2-fluorobenzyl)amino)ethoxy)pyrrolidin-3-yl)methyl)-4-methylpyridin-2-amine3tyl79.35no data
156NOS1Nitric oxide synthase, brainP29475jsrStructure of neuronal nitric oxide synthase R349A mutant heme domain in complex with 6-{{(3'S,4'R)-3'-[2""-(3'''-fluorophenethylamino)ethoxy]pyrrolidin-4'-yl}methyl}-4-methylpyridin-2-amine3nlo79.87no data
157NOS1Nitric oxide synthase, brainP29475ji1Structure of neuronal NOS heme domain in complex with a inhibitor (+-)-3-{cis-4'-[(6""-aminopyridin-2""-yl)methyl]pyrrolidin-3'-ylamino}propan-1-ol3b3m79.44no data
158NOS2Nitric oxide synthase, inducibleP35228NOS2Aat2Structure of human INOSOX with inhibitor AR-C957913e7g90.76no data
159NOS3Nitric oxide synthase, endothelialP29474s5dStructure of bovine endothelial nitric oxide synthase heme domain in complex with (R)-6-(2-Amino-2-(3-(2-(6-amino-4-methylpyridin-2-yl) ethyl)phenyl)ethyl)-4-methylpyridin-2-amine4cty82.63no data
160NOS3Nitric oxide synthase, endothelialP29474q1tStructure of bovine endothelial nitric oxide synthase heme domain in complex with 3-(2-(6-Amino-4-methylpyridin-2-yl)ethyl)-5-(methyl(2-(methylamino)ethyl)amino)benzonitrile4uha90.94no data
161NOS3Nitric oxide synthase, endothelialP29474pqwstructure of bovine endothelial nitric oxide synthase heme domain in complex with n'-[4-[[(2s,4r)-4-[3-[(c-thiophen-2-ylcarbonimidoyl)amino]phenoxy]pyrrolidin-2-yl]methoxy]phenyl]thiophene-2-carboximidamide4upt82.97no data
162NOS3Nitric oxide synthase, endothelialP29474knvStructure of human endothelial nitric oxide synthase heme domain in complex with (S)-6-(2,3-difluoro-5-(2-(1-methylazetidin-2-yl)ethyl)phenethyl)-4-methylpyridin-2-amine6nhf80.15no data
163NOS3Nitric oxide synthase, endothelialP29474kmsStructure of human endothelial nitric oxide synthase heme domain in complex with 6-(5-(3-(dimethylamino)propyl)-2,3,4-trifluorophenethyl)-4-methylpyridin-2-amine6nh881.77no data
164NOS3Nitric oxide synthase, endothelialP29474kmmStructure of human endothelial nitric oxide synthase heme domain in complex with 6-(3-(3-(dimethylamino)propyl)-2,5,6-trifluorophenethyl)-4-methylpyridin-2-amine6nh783.74no data
165NOS3Nitric oxide synthase, endothelialP29474kmaStructure of human endothelial nitric oxide synthase heme domain in complex with (R)-6-(3-fluoro-5-(2-(pyrrolidin-2-yl)ethyl)phenethyl)-4-methylpyridin-2-amine6nh285.38no data
166NOS3Nitric oxide synthase, endothelialP29474kldStructure of human endothelial nitric oxide synthase heme domain in complex with 6-(3-fluoro-5-(2-((2R,4S)-4-fluoro-1-methylpyrrolidin-2-yl)ethyl)phenethyl)-4-methylpyridin-2-amine6nh582.63no data
167NOS3Nitric oxide synthase, endothelialP29474klaStructure of human endothelial nitric oxide synthase heme domain in complex with 6-(3-fluoro-5-(2-((2R,4S)-4-fluoropyrrolidin-2-yl)ethyl)phenethyl)-4-methylpyridin-2-amine6nh483.18no data
168NOS3Nitric oxide synthase, endothelialP29474kl7Structure of the human endothelial nitric oxide synthase heme domain in complex with 6-(3-(3-(dimethylamino)propyl)-2,6-difluorophenethyl)-4-methylpyridin-2-amine6nh686.58no data
169NOS3Nitric oxide synthase, endothelialP29474kl4Structure of human endothelial nitric oxide synthase heme domain in complex with (S)-6-(3-fluoro-5-(2-(pyrrolidin-2-yl)ethyl)phenethyl)-4-methylpyridin-2-amine6nh392.07no data
170NOS3Nitric oxide synthase, endothelialP29474i5uStructure of bovine endothelial nitric oxide synthase heme domain in complex with N',N'-{[(2R)-3-aminopropane-1,2-diyl]bis(oxymethanediylbenzene-3,1-diyl)}dithiophene-2-carboximidamide4upq73.81no data
171NOS3Nitric oxide synthase, endothelialP29474f2jStructure of the human endothelial nitric oxide synthase heme domain in complex with N-(1-(Piperidin-4-yl)indolin-5-yl)thiophene-2-carboximidamide6cif87.42no data
172NOS3Nitric oxide synthase, endothelialP294747r2Structure of human endothelial nitric oxide synthase heme domain in complex with N-(1-(2-(Ethyl(methyl)amino)ethyl)-1,2,3,4-tetrahydroquino-lin-6-yl)thiophene-2-carboximidamide6cie80.86no data
173NOS3Nitric oxide synthase, endothelialP294746e5Structure of bovine endothelial nitric oxide synthase heme domain in complex with N-[3-({[(3S,5S)-5-{[(3-{[(Z)-imino(thiophen-2-yl)methyl]amino}benzyl)oxy]methyl}pyrrolidin-3-yl]oxy}methyl) phenyl]thiophene-2-carboximidamide4ups75.31no data
174NOS3Nitric oxide synthase, endothelialP29474ji5Structure of endothelial nitric oxide synthase heme domain complexed with N1-[(3'R,4'R)-4'-((6""-amino-4""-methylpyridin-2""-yl)methyl)pyrrolidin-3'-yl]-N2-(3'-fluorophenethyl)ethane-1,2-diamine tetrahydrochloride3jwx84.62no data
175NOS3Nitric oxide synthase, endothelialP294743xfStructure of endothelial nitric oxide synthase heme domain complexed with N1-{(3'S,4'S)-4'-[(6""-amino-4""-methylpyridin-2""-yl)methyl]pyrrolidin-3'-yl}- N2-(3'-fluorophenethyl)ethane-1,2-diamine tetrahydrochloride3nlt80.66no data
176NOS3Nitric oxide synthase, endothelialP29474hw0ALPHA-KETOGLUTARATE-DEPENDENT DIOXYGENASE COMPLEX14cwx80.68no data
177NOS3Nitric oxide synthase, endothelialP29474hw8Structure of bovine endothelial nitric oxide synthase heme domain in complex with 4-METHYL-6-(((3R,4R)-4-((5-(PYRIDIN-2-YL)PENTYL)OXY) PYRROLIDIN-3-YL)METHYL)PYRIDIN-2-AMINE4cwv76.49no data
178NOS3Nitric oxide synthase, endothelialP29474hw1Structure of bovine endothelial nitric oxide synthase heme domain in complex with 6-(5-(((3R,4R)-4-((6-AMINO-4-METHYLPYRIDIN-2-YL)METHYL) PYRROLIDIN-3-YL)OXY)PENTYL)-4-METHYLPYRIDIN-2-AMINE4cwy81.05no data
179NOS3Nitric oxide synthase, endothelialP294744v4Structure of bovine endothelial nitric oxide synthase heme domain in complex with N1-(3-(2-(6-Amino-4-methylpyridin-2-yl)ethyl)phenyl)-N1, N2-dimethylethane-1,2-diamine4uh791.17no data
180NOS3Nitric oxide synthase, endothelialP29474xebStructure of bovine endothelial nitric oxide synthase heme domain in complex with 7-((4-CHLORO-3-((METHYLAMINO)METHYL) PHENOXY)METHYL)QUINOLIN-2-AMINE in the absence of acetate5fj385.19no data
181NOS3Nitric oxide synthase, endothelialP294742snStructure of bovine endothelial nitric oxide synthase heme domain in complex with 7-(((3-((Dimethylamino)methyl)phenyl)amino)methyl) quinolin-2-amine5adn89.94no data
182NOS3Nitric oxide synthase, endothelialP29474m94Structure of bovine endothelial nitric oxide synthase heme domain in complex with 7-((3-(2-(Methylamino)ethyl)phenoxy)methyl)quinolin-2- amine5adj89.04no data
183NOS3Nitric oxide synthase, endothelialP294748j4Structure of human endothelial nitric oxide synthase heme domain in complex with 7-[(3-Ethyl-5-((methylamino)methyl)phenoxy)methyl]quinolin-2-amine5uo981.28no data
184NOS3Nitric oxide synthase, endothelialP29474m4rStructure of human endothelial nitric oxide synthase heme domain in complex with (R)-3-[(2-amino-4-methylquinolin-7-yl)methoxy]-5-(2-(methylamino)propyl)benzonitrile5uob89.61no data
185NOS3Nitric oxide synthase, endothelialP294748fdStructure of human endothelial nitric oxide synthase heme domain in complex with (S)-3-[(2-amino-4-methylquinolin-7-yl)methoxy]-5-(2-(methylamino)propyl)benzonitrile5uoc78no data
186NOS3Nitric oxide synthase, endothelialP294748eyStructure of human endothelial nitric oxide synthase heme domain in complex with 3-[(2-Amino-4-methylquinolin-7-yl)methoxy]-5-((methylamino)methyl)benzonitrile5uoa85.6no data
187NOS3Nitric oxide synthase, endothelialP29474xh8Structure of bovine endothelial nitric oxide synthase heme domain in complex with 7-(((3-(Pyridin-3-yl)propyl)amino)methyl)quinolin-2-amine5vv778.76no data
188NOS3Nitric oxide synthase, endothelialP29474w68Structure of human endothelial nitric oxide synthase heme domain in complex with 6-(3-Fluoro-5-(3-(methylamino)propyl)phenethyl)-4-methylpyridin-2-amine6av677.14no data
189NOS3Nitric oxide synthase, endothelialP29474w69Structure of human endothelial nitric oxide synthase heme domain in complex with HW696av786.97no data
190NOS3Nitric oxide synthase, endothelialP294748eyStructure of bovine endothelial nitric oxide synthase heme domain in complex with 3-[(2-Amino-4-methylquinolin-7-yl)methoxy]-5-((methylamino)methyl)benzonitrile5uod80.65no data
191NOS3Nitric oxide synthase, endothelialP29474w64Structure of bovine endothelial nitric oxide synthase heme domain in complex with 4-methyl-6-(2-(5-(4-methylpiperazin-1-yl)pyridin-3-yl) ethyl)pyridin-2-amine5fvy89.4no data
192NOS3Nitric oxide synthase, endothelialP29474xebStructure of bovine endothelial nitric oxide synthase heme domain in complex with 7-((4-CHLORO-3-((METHYLAMINO)METHYL) PHENOXY)METHYL)QUINOLIN-2-AMINE5fj283.83no data
193NOS3Nitric oxide synthase, endothelialP29474m85Structure of bovine endothelial nitric oxide synthase heme domain in complex with 7-((3-(Methylamino)methyl)phenoxy)methyl)quinolin-2- amine5adl88.97no data
194NOS3Nitric oxide synthase, endothelialP294747m3Structure of bovine endothelial nitric oxide synthase heme domain in complex with 7-((3-(Dimethylamino)methyl)phenoxy)methyl)quinolin-2- amine5adk87.05no data
195NOS3Nitric oxide synthase, endothelialP29474s85Structure of bovine endothelial nitric oxide synthase heme domain in complex with N1-(3-(2-(6-Amino-4-methylpyridin-2-yl)ethyl)-5- fluorophenyl)-N1,N2-dimethylethane-1,2-diamine4uh990.47no data
196NOS3Nitric oxide synthase, endothelialP29474qj8Structure of bovine endothelial nitric oxide synthase heme domain in complex with 6-((((3R,5S)-5-(((6-amino-4-methylpyridin-2-yl)methoxy)methyl)pyrrolidin-3-yl)oxy)methyl)-4-methylpyridin-2-amine4luw80no data
197NOS3Nitric oxide synthase, endothelialP29474at2Structure of bovine eNOS oxygenase domain with inhibitor AR-C957913e7s86.12no data