The Ligandable Human Proteome

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Ureohydrolase

IndexGene Name PrimaryProtein NameUniprot IDGene Name SynonymLigand NameStructurePDB Codeligand desolvationLigand StructureCompound Affinity nM
1ARGI1Arginase-1P05089x7aCrystal structure of human Arginase-1 complexed with inhibitor 94hww73.01223.
2ARGI1Arginase-1P05089x8aCrystal structure of human Arginase-1 complexed with inhibitor 144hxq73.0860.
3ARGI2Arginase-2, mitochondrialP78540xa1Crystal structure of human Arginase-2 complexed with inhibitor 2d: {(5R)-5-amino-5-carboxy-5-[1-(4-chlorobenzyl)piperidin-4-yl]pentyl}(trihydroxy)borate(1-)4ixv59.92240.
4ARGI2Arginase-2, mitochondrialP78540x7aCrystal structure of human Arginase-2 complexed with inhibitor 94hze72.62509.
5ARGI2Arginase-2, mitochondrialP7854038iCrystal structure of human Arginase-2 complexed with inhibitor 11d: {(5R)-5-amino-5-carboxy-5-[(3-endo)-8-(3,4-dichlorobenzyl)-8-azabicyclo[3.2.1]oct-3-yl]pentyl}(trihydroxy)borate(1-)4ixu66.1823.
6ARGI2Arginase-2, mitochondrialP78540x8aCrystal structure of human Arginase-2 complexed with inhibitor 144i0671.7167.