The Ligandable Human Proteome

Index	Gene Name Primary	Protein Name	Uniprot ID	Gene Name Synonym	Ligand Name	Structure	PDB Code	ligand desolvation	Compound Affinity nM
1	MEN1	Menin	O00255	SCG2	fnv	Menin in complex with MI-1482	6by8	81.65	no data
2	MEN1	Menin	O00255	SCG2	eev	Menin in complex with MI-1481	6bxy	83.91	no data
3	MEN1	Menin	O00255	SCG2	ee7	Menin in complex with MI-853	6bxh	75.71	no data
4	MEN1	Menin	O00255	SCG2	6e6	Menin in complex with MI-352	5db0	89.37	no data
5	MEN1	Menin	O00255	SCG2	58r	Menin in complex with MI-389	5db2	76.75	25.
6	MEN1	Menin	O00255	SCG2	58q	Menin in complex with MI-574	5db3	73.24	12.
7	MEN1	Menin	O00255	SCG2	58p	Menin in complex with MI-352	5db0	86.28	37.
8	MEN1	Menin	O00255	SCG2	58o	Menin in complex with MI-336	5db1	72.19	22.
9	MEN1	Menin	O00255	SCG2	3xy	menin in complex with MI-136	4x5z	74.37	23.6
10	MEN1	Menin	O00255	SCG2	3xw	Menin in complex with MI-503	4x5y	74.89	9.3
11	MEN1	Menin	O00255	SCG2	2vk	Human menin with bound inhibitor MIV-3S	4og4	75.92	952.
12	MEN1	Menin	O00255	SCG2	2s9	Human menin with bound inhibitor MIV-4	4og6	70.57	197.
13	MEN1	Menin	O00255	SCG2	2s6	Human menin with bound inhibitor MIV-3R	4og3	69.88	285.
14	MEN1	Menin	O00255	SCG2	0br	Crystal structure of human menin in complex with MLL1 and LEDGF	3u88	94.23	no data
15	MEN1	Menin	O00255	SCG2	0ro	Human menin with bound inhibitor MI-2	4gq3	76.71	no data
16	MEN1	Menin	O00255	SCG2	0rt	Human menin with bound inhibitor MI-2-2	4gq4	77.77	22.
17	MEN1	Menin	O00255	SCG2	2s7	Human menin with bound inhibitor MIV-5	4og5	76.46	302.
18	MEN1	Menin	O00255	SCG2	2se	Human menin with bound inhibitor MIV-7	4og7	70.32	114.
19	MEN1	Menin	O00255	SCG2	2sf	Human menin with bound inhibitor MIV-6R	4og8	77.96	56.
20	MEN1	Menin	O00255	SCG2	59k	Menin in complex with MI-326	5dd9	76.57	779.
21	MEN1	Menin	O00255	SCG2	59m	Menin in complex with MI-333	5dda	78.06	1653.
22	MEN1	Menin	O00255	SCG2	59q	Menin in complex with MI-319	5ddb	78.41	82.
23	MEN1	Menin	O00255	SCG2	59v	Menin in complex with MI-2-3	5ddc	78.06	92.
24	MEN1	Menin	O00255	SCG2	59x	menin in complex with MI-836	5ddd	78.61	260.
25	MEN1	Menin	O00255	SCG2	5a0	Menin in complex with MI-859	5dde	87.39	65.

The Ligandable Human Proteome

Menin