The Ligandable Human Proteome

Index	Gene Name Primary	Protein Name	Uniprot ID	Ligand Name	Structure	PDB Code	ligand desolvation	Compound Affinity nM
1	F263	6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3	Q16875	haw	Human PFKFB3 in complex with a N-Aryl 6-Aminoquinoxaline inhibitor 7	6ibz	87	no data
2	F263	6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3	Q16875	hak	Human PFKFB3 in complex with a N-Aryl 6-Aminoquinoxaline inhibitor 4	6ic0	95.3	no data
3	F263	6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3	Q16875	gv8	Human PFKFB3 in complex with a N-Aryl 6-Aminoquinoxaline inhibitor 3	6hvj	91.99	no data
4	F263	6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3	Q16875	gv5	Human PFKFB3 in complex with a N-Aryl 6-Aminoquinoxaline inhibitor 2	6hvi	95.88	no data
5	F263	6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3	Q16875	bww	HUMAN PFKFB3 IN COMPLEX WITH KAN0438241	6etj	92.02	no data
6	F263	6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3	Q16875	bki	human PFKFB3 in complex with a pyrrolopyrimidone compound	4d4j	93.88	no data
7	F263	6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3	Q16875	bkv	human PFKFB3 in complex with a pyrrolopyrimidone compound	4d4m	95.56	no data
8	F263	6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3	Q16875	8v1	Human PFKFB3 in complex with an indole inhibitor 6	5ak0	84.73	21.
9	F263	6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3	Q16875	fd9	Human PFKFB3 in complex with an indole inhibitor 3	5ajx	79.32	11.
10	F263	6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3	Q16875	gv2	Human PFKFB3 in complex with a N-Aryl 6-Aminoquinoxaline inhibitor 1	6hvh	90.43	no data
11	F263	6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3	Q16875	h9z	Human PFKFB3 in complex with a N-Aryl 6-Aminoquinoxaline inhibitor 5	6ibx	88.28	no data
12	F263	6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3	Q16875	hat	Human PFKFB3 in complex with a N-Aryl 6-Aminoquinoxaline inhibitor 6	6iby	89.24	no data

The Ligandable Human Proteome

6-phosphofructo-2-kinase