Index | Gene Name Primary | Protein Name | Uniprot ID | Gene Name Synonym | Ligand Name | Structure | PDB Code | ligand desolvation | Ligand Structure | Compound Affinity nM |
1 | 1433S | 14-3-3 protein sigma | P31947 | HME1 | gf8 | Ternary complex of Estrogen Receptor alpha peptide and 14-3-3 sigma C42 mutant bound to disulfide fragment PPI stabilizer 5 | 6hn2 | 70.18 | | no data |
2 | 1433S | 14-3-3 protein sigma | P31947 | HME1 | 0dv | Crystal structure of human 14-3-3 sigma in complex with TASK-3 peptide and stabilizer Fusicoccin H | 3ux0 | 61.65 | | no data |
3 | 1433S | 14-3-3 protein sigma | P31947 | HME1 | fw1 | Crystal structure of human 14-3-3 sigma C38N/N166H in complex with TASK-3 peptide and stabilizer Fusicoccin A aglycone | 3sml | 67.11 | | no data |
4 | 1433S | 14-3-3 protein sigma | P31947 | HME1 | 0v4 | Crystal structure of human 14-3-3 sigma in complex with TASK-3 peptide and stabilizer 16-O-Me-FC-H | 4fr3 | 65.32 | | no data |
5 | 1433Z | 14-3-3 protein zeta/delta | P63104 | | 5so | Small-molecule stabilization of the 14-3-3/Gab2 PPI interface | 5exa | 70.46 | | no data |