Index | Gene Name Primary | Protein Name | Uniprot ID | Gene Name Synonym | Ligand Name | Structure | PDB Code | ligand desolvation | Ligand Structure | Compound Affinity nM |
1 | IDHC | Isocitrate dehydrogenase [NADP] cytoplasmic | O75874 | PICD | dwg | Novel Modes of Inhibition of Wild-Type IDH1: Direct Covalent Modification of His315 with Cmpd13 | 6bl1 | 77.38 | | no data |
2 | IDHC | Isocitrate dehydrogenase [NADP] cytoplasmic | O75874 | PICD | 59d | Crystal structure of human IDH1 in complex with GSK321A | 5de1 | 90.52 | | no data |
3 | IDHC | Isocitrate dehydrogenase [NADP] cytoplasmic | O75874 | PICD | 6n3 | Crystal structure of Iso-citrate Dehydrogenase R132H in complex with a novel inhibitor (compound 13a) | 5l57 | 75.05 | | no data |
4 | IDHC | Isocitrate dehydrogenase [NADP] cytoplasmic | O75874 | PICD | 70q | IDH1 R132H in complex with IDH146 | 5sun | 71.87 | | no data |
5 | IDHC | Isocitrate dehydrogenase [NADP] cytoplasmic | O75874 | PICD | dwp | Novel Modes of Inhibition of Wild-Type IDH1: Direct Covalent Modification of His315 with Cmpd1 | 6bkx | 76.25 | | no data |
6 | IDHC | Isocitrate dehydrogenase [NADP] cytoplasmic | O75874 | PICD | dwj | Novel Modes of Inhibition of Wild-Type IDH1:Direct Covalent Modification of His315 with Cmpd11 | 6bl0 | 76.43 | | no data |
7 | IDHC | Isocitrate dehydrogenase [NADP] cytoplasmic | O75874 | PICD | dws | Novel Modes of Inhibition of Wild-Type IDH1: Direct Covalent Modification of His315 with Cmpd15 | 6bl2 | 75.14 | | no data |