| Index | Gene Name Primary | Uniprot ID | Protein Name | Gene Name Synonym | PDB codes |
| 1 | SIRT1 | Q96EB6 | NAD-dependent protein deacetylase sirtuin-1 | SIR2L1 | 4i5i 4if6 4ig9 4kxq 4zzi 4zzj |
| 2 | SIRT2 | Q8IXJ6 | NAD-dependent protein deacetylase sirtuin-2 | SIR2L SIR2L2 | 1j8f 3zgo 3zgv 4l3o 4r8m 4rmg 4rmh 4rmi 4rmj 4x3o 4x3p 4y6l 4y6o 4y6q 5d7o 5d7p 5d7q 5dy4 5dy5 5fyq 5g4c 5mat 5y0z 5y5n 5yql 5yqm 5yqn 5yqo 5mar |
| 3 | SIRT3 | Q9NTG7 | NAD-dependent protein deacetylase sirtuin-3, mitochondrial | SIR2L3 | 3glr 3gls 3glt 3glu 4bn4 4bv3 4bvb 4bve 4bvf 4bvg 4bvh 4c78 4c7b 4fvt 4fz3 4hd8 4jsr 4jt8 4jt9 4o8z 5bwn 5bwo 5d7n 5y4h 5ytk 5z93 5z94 5zgc 6iso |
| 4 | SIRT5 | Q9NXA8 | NAD-dependent protein deacylase sirtuin-5, mitochondrial | SIR2L5 | 2b4y 2nyr 3rig 3riy 4f4u 4f56 4g1c 4hda 5bwl 5xhs 6eqs 6ace 6acl 6aco 6acp |
| 5 | SIRT6 | Q8N6T7 | NAD-dependent protein deacetylase sirtuin-6 | SIR2L6 | 3k35 3pki 3pkj 3zg6 5mf6 5mfp 5mfz 5mgn 5x16 5y2f 6hoy |