The Ligandable Human Proteome

Serine proteases, trypsin domain

Index	Gene Name Primary	Protein Name	Gene Name Synonym	Uniprot ID
1				E7EML9
2				Q6ZR98
3	ACR	Acrosin	ACRS	P10323
4	AZU1	Azurocidin		P20160
5	C1R	Complement C1r subcomponent		P00736
6	C1RL	Complement C1r subcomponent-like protein	C1RL1 C1RLP CLSPA	Q9NZP8
7	C1S	Complement C1s subcomponent		P09871
8	C2	Complement C2		P06681
9	CELA1	Chymotrypsin-like elastase family member 1	ELA1	Q9UNI1
10	CELA2A	Chymotrypsin-like elastase family member 2A	ELA2A	P08217
11	CELA2B	Chymotrypsin-like elastase family member 2B	ELA2B	P08218
12	CELA3A	Chymotrypsin-like elastase family member 3A	ELA3 ELA3A	P09093
13	CELA3B	Chymotrypsin-like elastase family member 3B	ELA3B	P08861
14	CFB	Complement factor B	BF BFD	P00751
15	CFD	Complement factor D	DF PFD	P00746
16	CFI	Complement factor I	IF	P05156
17	CMA1	Chymase	CYH CYM	P23946
18	CORIN	Atrial natriuretic peptide-converting enzyme	CRN TMPRSS10	Q9Y5Q5
19	CTRB1	Chymotrypsinogen B	CTRB	P17538
20	CTRB2	Chymotrypsinogen B2		Q6GPI1
21	CTRC	Chymotrypsin-C	CLCR	Q99895
22	CTRL	Chymotrypsin-like protease CTRL-1	CTRL1	P40313
23	CTSG	Cathepsin G		P08311
24	ELANE	Neutrophil elastase	ELA2	P08246
25	F10	Coagulation factor X		P00742
26	F11	Coagulation factor XI		P03951
27	F12	Coagulation factor XII		P00748
28	F2	Prothrombin		P00734
29	F7	Coagulation factor VII		P08709
30	F9	Coagulation factor IX		P00740
31	GZMA	Granzyme A	CTLA3 HFSP	P12544
32	GZMB	Granzyme B	CGL1 CSPB CTLA1 GRB	P10144
33	GZMH	Granzyme H	CGL2 CTSGL2	P20718
34	GZMK	Granzyme K	TRYP2	P49863
35	GZMM	Granzyme M	MET1	P51124
36	HABP2	Hyaluronan-binding protein 2	HGFAL PHBP	Q14520
37	HGF	Hepatocyte growth factor	HPTA	P14210
38	HGFAC	Hepatocyte growth factor activator		Q04756
39	HP	Haptoglobin		P00738
40	HPN	Serine protease hepsin	TMPRSS1	P05981
41	HPR	Haptoglobin-related protein		P00739
42	KLK1	Kallikrein-1		P06870
43	KLK10	Kallikrein-10	NES1 PRSSL1	O43240
44	KLK11	Kallikrein-11	PRSS20 TLSP	Q9UBX7
45	KLK12	Kallikrein-12	KLKL5	Q9UKR0
46	KLK13	Kallikrein-13	KLKL4	Q9UKR3
47	KLK14	Kallikrein-14	KLKL6	Q9P0G3
48	KLK15	Kallikrein-15		Q9H2R5
49	KLK2	Kallikrein-2		P20151
50	KLK3	Prostate-specific antigen	APS	P07288
51	KLK4	Kallikrein-4	EMSP1 PRSS17 PSTS	Q9Y5K2
52	KLK5	Kallikrein-5	SCTE	Q9Y337
53	KLK6	Kallikrein-6	PRSS18 PRSS9	Q92876
54	KLK7	Kallikrein-7	PRSS6 SCCE	P49862
55	KLK8	Kallikrein-8	NRPN PRSS19 TADG14	O60259
56	KLK9	Kallikrein-9		Q9UKQ9
57	KLKB1	Plasma kallikrein	KLK3	P03952
58	LPA	Apolipoprotein(a)		P08519
59	MASP1	Mannan-binding lectin serine protease 1	CRARF CRARF1 PRSS5	P48740
60	MASP2	Mannan-binding lectin serine protease 2		O00187
61	MST1	Hepatocyte growth factor-like protein	D3F15S2 DNF15S2 HGFL	P26927
62	MST1L	Putative macrophage stimulating 1-like protein	D1F15S1A MST1P9 MSTP9	Q2TV78
63	OVCH1	Ovochymase-1		Q7RTY7
64	OVCH2	Ovochymase-2	OVTN	Q7RTZ1
65	PAMR1	Inactive serine protease PAMR1	RAMP	Q6UXH9
66	PLAT	Tissue-type plasminogen activator		P00750
67	PLAU	Urokinase-type plasminogen activator		P00749
68	PLG	Plasminogen		P00747
69	PROC	Vitamin K-dependent protein C		P04070
70	PROZ	Vitamin K-dependent protein Z		P22891
71	PRSS1	Trypsin-1	TRP1 TRY1 TRYP1	P07477
72	PRSS12	Neurotrypsin		P56730
73	PRSS2	Trypsin-2	TRY2 TRYP2	P07478
74	PRSS21	Testisin	ESP1 TEST1	Q9Y6M0
75	PRSS22	Brain-specific serine protease 4	BSSP4 PRSS26	Q9GZN4
76	PRSS23	Serine protease 23	ZSIG13	O95084
77	PRSS27	Serine protease 27	MPN	Q9BQR3
78	PRSS29P	Putative serine protease 29	ISP2	A6NIE9
79	PRSS3	Trypsin-3	PRSS4 TRY3 TRY4	P35030
80	PRSS33	Serine protease 33		Q8NF86
81	PRSS35	Inactive serine protease 35	C6orf158	Q8N3Z0
82	PRSS36	Polyserase-2		Q5K4E3
83	PRSS37	Probable inactive serine protease 37	TRYX2	A4D1T9
84	PRSS38	Serine protease 38	MPN2	A1L453
85	PRSS3P2	Putative trypsin-6	T6 TRY6	Q8NHM4
86	PRSS41	Serine protease 41	TESSP1	Q7RTY9
87	PRSS42P	Putative serine protease 42	PRSS42 TESSP2	Q7Z5A4
88	PRSS45P	Putative serine protease 45	PRSS45 TESSP5	Q7RTY3
89	PRSS46P	Putative serine protease 46	PRSS46	E5RG02
90	PRSS47	Putative serine protease 47		A8MTI9
91	PRSS48	Serine protease 48	ESSPL	Q7RTY5
92	PRSS50	Probable threonine protease PRSS50	CT20 TSP50	Q9UI38
93	PRSS51	Serine protease-like protein 51		A0A1B0GVH4
94	PRSS53	Serine protease 53		Q2L4Q9
95	PRSS54	Inactive serine protease 54	KLKBL4	Q6PEW0
96	PRSS55	Serine protease 55	TSP1	Q6UWB4
97	PRSS56	Serine protease 56		P0CW18
98	PRSS57	Serine protease 57	PRSSL1	Q6UWY2
99	PRSS58	Serine protease 58	TRY1 TRYX3	Q8IYP2
100	PRSS8	Prostasin		Q16651
101	PRTN3	Myeloblastin	MBN	P24158
102	ST14	Suppressor of tumorigenicity 14 protein	PRSS14 SNC19 TADG15	Q9Y5Y6
103	TMPRSS11A	Transmembrane protease serine 11A	ECRG1 HATL1 HESP	Q6ZMR5
104	TMPRSS11B	Transmembrane protease serine 11B	HATL5	Q86T26
105	TMPRSS11D	Transmembrane protease serine 11D	HAT	O60235
106	TMPRSS11E	Transmembrane protease serine 11E	DESC1 TMPRSS11E2	Q9UL52
107	TMPRSS11F	Transmembrane protease serine 11F	HATL4	Q6ZWK6
108	TMPRSS12	Transmembrane protease serine 12		Q86WS5
109	TMPRSS13	Transmembrane protease serine 13	MSP TMPRSS11	Q9BYE2
110	TMPRSS15	Enteropeptidase	ENTK PRSS7	P98073
111	TMPRSS2	Transmembrane protease serine 2	PRSS10	O15393
112	TMPRSS3	Transmembrane protease serine 3	ECHOS1 TADG12	P57727
113	TMPRSS4	Transmembrane protease serine 4	TMPRSS3	Q9NRS4
114	TMPRSS5	Transmembrane protease serine 5		Q9H3S3
115	TMPRSS6	Transmembrane protease serine 6		Q8IU80
116	TMPRSS7	Transmembrane protease serine 7		Q7RTY8
117	TMPRSS9	Transmembrane protease serine 9		Q7Z410
118	TPSAB1	Tryptase alpha/beta-1	TPS1 TPS2 TPSB1	Q15661
119	TPSB2	Tryptase beta-2	TPS2	P20231
120	TPSD1	Tryptase delta		Q9BZJ3
121	TPSG1	Tryptase gamma	PRSS31 TMT	Q9NRR2