The Ligandable Human Proteome

PDZ domain

Index	Gene Name Primary	Protein Name	Gene Name Synonym	Uniprot ID
1	AFDN	Afadin	AF6 MLLT4	P55196
2	AHNAK	Neuroblast differentiation-associated protein AHNAK	PM227	Q09666
3	AHNAK2	Protein AHNAK2	C14orf78 KIAA2019	Q8IVF2
4	APBA1	Amyloid-beta A4 precursor protein-binding family A member 1	MINT1 X11	Q02410
5	APBA2	Amyloid-beta A4 precursor protein-binding family A member 2	MINT2 X11L	Q99767
6	APBA3	Amyloid-beta A4 precursor protein-binding family A member 3	MINT3 X11L2	O96018
7	ARHGAP21	Rho GTPase-activating protein 21	ARHGAP10 KIAA1424	Q5T5U3
8	ARHGAP23	Rho GTPase-activating protein 23	KIAA1501	Q9P227
9	ARHGEF11	Rho guanine nucleotide exchange factor 11	KIAA0380	O15085
10	ARHGEF12	Rho guanine nucleotide exchange factor 12	KIAA0382 LARG	Q9NZN5
11	CARD14	Caspase recruitment domain-containing protein 14	CARMA2	Q9BXL6
12	CASK	Peripheral plasma membrane protein CASK	LIN2	O14936
13	CNK3/IPCEF1	CNK3/IPCEF1 fusion protein		G9CGD6
14	CNKSR1	Connector enhancer of kinase suppressor of ras 1	CNK1	Q969H4
15	CNKSR2	Connector enhancer of kinase suppressor of ras 2	CNK2 KIAA0902 KSR2	Q8WXI2
16	CNKSR3	Connector enhancer of kinase suppressor of ras 3	MAGI1	Q6P9H4
17	CYTIP	Cytohesin-interacting protein	PSCDBP	O60759
18	DEPTOR	DEP domain-containing mTOR-interacting protein	DEPDC6	Q8TB45
19	DLG1	Disks large homolog 1		Q12959
20	DLG2	Disks large homolog 2		Q15700
21	DLG3	Disks large homolog 3	KIAA1232	Q92796
22	DLG4	Disks large homolog 4	PSD95	P78352
23	DLG5	Disks large homolog 5	KIAA0583 PDLG	Q8TDM6
24	DVL1	Segment polarity protein dishevelled homolog DVL-1		O14640
25	DVL1P1	Putative segment polarity protein dishevelled homolog DVL1P1	DVL DVL1 DVL1L1	P54792
26	DVL2	Segment polarity protein dishevelled homolog DVL-2		O14641
27	DVL3	Segment polarity protein dishevelled homolog DVL-3	KIAA0208	Q92997
28	ERBIN	Erbin	ERBB2IP KIAA1225 LAP2	Q96RT1
29	FRMPD1	FERM and PDZ domain-containing protein 1	FRMD2 KIAA0967	Q5SYB0
30	FRMPD2	FERM and PDZ domain-containing protein 2	PDZD5C PDZK4 PDZK5C	Q68DX3
31	FRMPD2B	Putative protein FRMPD2-like	FRMPD2L1 FRMPD2L2 FRMPD2P1 FRMPD2P2 PDZD5A PDZD5B PDZK5A PDZK5B	Q6IN97
32	FRMPD3	FERM and PDZ domain-containing protein 3	KIAA1817	Q5JV73
33	FRMPD4	FERM and PDZ domain-containing protein 4	KIAA0316 PDZD10 PDZK10	Q14CM0
34	GIPC1	PDZ domain-containing protein GIPC1	C19orf3 GIPC RGS19IP1	O14908
35	GIPC2	PDZ domain-containing protein GIPC2		Q8TF65
36	GIPC3	PDZ domain-containing protein GIPC3	C19orf64	Q8TF64
37	GOPC	Golgi-associated PDZ and coiled-coil motif-containing protein	CAL FIG	Q9HD26
38	GRASP	General receptor for phosphoinositides 1-associated scaffold protein		Q7Z6J2
39	GRID2IP	Delphilin		A4D2P6
40	GRIP1	Glutamate receptor-interacting protein 1		Q9Y3R0
41	GRIP2	Glutamate receptor-interacting protein 2	KIAA1719	Q9C0E4
42	HTRA1	Serine protease HTRA1	HTRA PRSS11	Q92743
43	HTRA2	Serine protease HTRA2, mitochondrial	OMI PRSS25	O43464
44	HTRA3	Serine protease HTRA3	PRSP	P83110
45	HTRA4	Serine protease HTRA4		P83105
46	IL16	Pro-interleukin-16 [Cleaved into: Interleukin-16		Q14005
47	INTU	Protein inturned	KIAA1284 PDZD6 PDZK6	Q9ULD6
48	LDB3	LIM domain-binding protein 3	KIAA0613 ZASP	O75112
49	LIMK1	LIM domain kinase 1	LIMK	P53667
50	LIMK2	LIM domain kinase 2		P53671
51	LIN7A	Protein lin-7 homolog A	MALS1 VELI1	O14910
52	LIN7B	Protein lin-7 homolog B	MALS2 VELI2	Q9HAP6
53	LIN7C	Protein lin-7 homolog C	MALS3 VELI3	Q9NUP9
54	LMO7	LIM domain only protein 7	FBX20 FBXO20 KIAA0858	Q8WWI1
55	LNX1	E3 ubiquitin-protein ligase LNX	LNX PDZRN2	Q8TBB1
56	LNX2	Ligand of Numb protein X 2	PDZRN1	Q8N448
57	LRRC7	Leucine-rich repeat-containing protein 7	KIAA1365 LAP1	Q96NW7
58	MAGI1	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1	AIP3 BAIAP1 BAP1 TNRC19	Q96QZ7
59	MAGI2	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2	ACVRINP1 AIP1 KIAA0705	Q86UL8
60	MAGI3	Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 3	KIAA1634	Q5TCQ9
61	MAGIX	PDZ domain-containing protein MAGIX		Q9H6Y5
62	MAST1	Microtubule-associated serine/threonine-protein kinase 1	KIAA0973 SAST	Q9Y2H9
63	MAST2	Microtubule-associated serine/threonine-protein kinase 2	KIAA0807 MAST205	Q6P0Q8
64	MAST3	Microtubule-associated serine/threonine-protein kinase 3	KIAA0561	O60307
65	MAST4	Microtubule-associated serine/threonine-protein kinase 4	KIAA0303	O15021
66	MPDZ	Multiple PDZ domain protein	MUPP1	O75970
67	MPP1	55 kDa erythrocyte membrane protein	DXS552E EMP55	Q00013
68	MPP2	MAGUK p55 subfamily member 2	DLG2	Q14168
69	MPP3	MAGUK p55 subfamily member 3	DLG3	Q13368
70	MPP4	MAGUK p55 subfamily member 4	ALS2CR5 DLG6	Q96JB8
71	MPP5	MAGUK p55 subfamily member 5	PALS1	Q8N3R9
72	MPP6	MAGUK p55 subfamily member 6	VAM1	Q9NZW5
73	MPP7	MAGUK p55 subfamily member 7		Q5T2T1
74	MYO18A	Unconventional myosin-XVIIIa	CD245 KIAA0216 MYSPDZ	Q92614
75	NOS1	Nitric oxide synthase, brain		P29475
76	PARD3	Partitioning defective 3 homolog	PAR3 PAR3A	Q8TEW0
77	PARD3B	Partitioning defective 3 homolog B	ALS2CR19 PAR3B PAR3L	Q8TEW8
78	PARD6A	Partitioning defective 6 homolog alpha	PAR6A	Q9NPB6
79	PARD6B	Partitioning defective 6 homolog beta	PAR6B	Q9BYG5
80	PARD6G	Partitioning defective 6 homolog gamma	PAR6G	Q9BYG4
81	PATJ	InaD-like protein	CIPP INADL	Q8NI35
82	PCLO	Protein piccolo	ACZ KIAA0559	Q9Y6V0
83	PDLIM1	PDZ and LIM domain protein 1	CLIM1 CLP36	O00151
84	PDLIM2	PDZ and LIM domain protein 2		Q96JY6
85	PDLIM3	PDZ and LIM domain protein 3	ALP	Q53GG5
86	PDLIM4	PDZ and LIM domain protein 4	RIL	P50479
87	PDLIM5	PDZ and LIM domain protein 5	ENH	Q96HC4
88	PDLIM7	PDZ and LIM domain protein 7	ENIGMA	Q9NR12
89	PDZD11	PDZ domain-containing protein 11	AIPP1 PDZK11 PISP	Q5EBL8
90	PDZD2	PDZ domain-containing protein 2	AIPC KIAA0300 PDZK3	O15018
91	PDZD3	Na(+)/H(+) exchange regulatory cofactor NHE-RF4	IKEPP NHERF4 PDZK2	Q86UT5
92	PDZD4	PDZ domain-containing protein 4	KIAA1444 PDZK4 PDZRN4L	Q76G19
93	PDZD7	PDZ domain-containing protein 7	PDZK7	Q9H5P4
94	PDZD8	PDZ domain-containing protein 8	PDZK8	Q8NEN9
95	PDZD9	PDZ domain-containing protein 9	C16orf65	Q8IXQ8
96	PDZK1	Na(+)/H(+) exchange regulatory cofactor NHE-RF3	CAP70 NHERF3 PDZD1	Q5T2W1
97	PDZK1P1	Putative PDZ domain-containing protein PDZK1P1	PDZK1P2	A8MUH7
98	PDZRN3	E3 ubiquitin-protein ligase PDZRN3	KIAA1095 LNX3 SEMCAP3	Q9UPQ7
99	PDZRN4	PDZ domain-containing RING finger protein 4	LNX4 SEMCAP3L	Q6ZMN7
100	PICK1	PRKCA-binding protein	PRKCABP	Q9NRD5
101	PPP1R9A	Neurabin-1	KIAA1222	Q9ULJ8
102	PPP1R9B	Neurabin-2	PPP1R6	Q96SB3
103	PREX1	Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein	KIAA1415	Q8TCU6
104	PREX2	Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 2 protein	DEPDC2	Q70Z35
105	PRX	Periaxin	KIAA1620	Q9BXM0
106	PSMD9	26S proteasome non-ATPase regulatory subunit 9		O00233
107	PTPN13	Tyrosine-protein phosphatase non-receptor type 13	PNP1 PTP1E PTPL1	Q12923
108	PTPN3	Tyrosine-protein phosphatase non-receptor type 3	PTPH1	P26045
109	PTPN4	Tyrosine-protein phosphatase non-receptor type 4		P29074
110	RADIL	Ras-associating and dilute domain-containing protein	KIAA1849	Q96JH8
111	RAPGEF2	Rap guanine nucleotide exchange factor 2	KIAA0313 NRAPGEP PDZGEF1	Q9Y4G8
112	RAPGEF6	Rap guanine nucleotide exchange factor 6	PDZGEF2	Q8TEU7
113	RGS12	Regulator of G-protein signaling 12		O14924
114	RGS3	Regulator of G-protein signaling 3		P49796
115	RHPN1	Rhophilin-1	KIAA1929	Q8TCX5
116	RHPN2	Rhophilin-2		Q8IUC4
117	RHPN2P1	Putative rhophilin-2-like protein RHPN2P1		A8MT19
118	RIMS1	Regulating synaptic membrane exocytosis protein 1	KIAA0340 RAB3IP2 RIM1	Q86UR5
119	RIMS2	Regulating synaptic membrane exocytosis protein 2	KIAA0751 RAB3IP3 RIM2	Q9UQ26
120	SCRIB	Protein scribble homolog	CRIB1 KIAA0147 LAP4 SCRB1 VARTUL	Q14160
121	SDCBP	Syntenin-1	MDA9 SYCL	O00560
122	SDCBP2	Syntenin-2	SITAC18	Q9H190
123	SHANK1	SH3 and multiple ankyrin repeat domains protein 1		Q9Y566
124	SHANK2	SH3 and multiple ankyrin repeat domains protein 2	CORTBP1 KIAA1022 PROSAP1	Q9UPX8
125	SHANK3	SH3 and multiple ankyrin repeat domains protein 3	KIAA1650 PROSAP2 PSAP2	Q9BYB0
126	SHROOM2	Protein Shroom2	APXL	Q13796
127	SHROOM3	Protein Shroom3	KIAA1481 SHRML	Q8TF72
128	SHROOM4	Protein Shroom4	KIAA1202 SHAP	Q9ULL8
129	SIPA1	Signal-induced proliferation-associated protein 1	SPA1	Q96FS4
130	SIPA1L1	Signal-induced proliferation-associated 1-like protein 1	E6TP1 KIAA0440	O43166
131	SIPA1L2	Signal-induced proliferation-associated 1-like protein 2	KIAA1389	Q9P2F8
132	SIPA1L3	Signal-induced proliferation-associated 1-like protein 3	KIAA0545 SPAL3	O60292
133	SLC9A3R1	Na(+)/H(+) exchange regulatory cofactor NHE-RF1	NHERF NHERF1	O14745
134	SLC9A3R2	Na(+)/H(+) exchange regulatory cofactor NHE-RF2	NHERF2	Q15599
135	SNTA1	Alpha-1-syntrophin	SNT1	Q13424
136	SNTB1	Beta-1-syntrophin	SNT2B1	Q13884
137	SNTB2	Beta-2-syntrophin	D16S2531E SNT2B2 SNTL	Q13425
138	SNTG1	Gamma-1-syntrophin		Q9NSN8
139	SNTG2	Gamma-2-syntrophin		Q9NY99
140	SNX27	Sorting nexin-27	KIAA0488	Q96L92
141	STXBP4	Syntaxin-binding protein 4		Q6ZWJ1
142	SYNJ2BP	Synaptojanin-2-binding protein	OMP25	P57105
143	SYNPO2	Synaptopodin-2		Q9UMS6
144	SYNPO2L	Synaptopodin 2-like protein		Q9H987
145	TAX1BP3	Tax1-binding protein 3	TIP1	O14907
146	TIAM1	T-lymphoma invasion and metastasis-inducing protein 1		Q13009
147	TIAM2	T-lymphoma invasion and metastasis-inducing protein 2	KIAA2016 STEF	Q8IVF5
148	TJP1	Tight junction protein ZO-1	ZO1	Q07157
149	TJP2	Tight junction protein ZO-2	X104 ZO2	Q9UDY2
150	TJP3	Tight junction protein ZO-3	ZO3	O95049
151	USH1C	Harmonin	AIE75	Q9Y6N9
152	WHRN	Whirlin	DFNB31 KIAA1526	Q9P202