The Ligandable Human Proteome

EF-hand domain

Index	Gene Name Primary	Protein Name	Gene Name Synonym	Uniprot ID
1	ACTN1	Alpha-actinin-1		P12814
2	ACTN2	Alpha-actinin-2		P35609
3	ACTN3	Alpha-actinin-3		Q08043
4	ACTN4	Alpha-actinin-4		O43707
5	AIF1	Allograft inflammatory factor 1	G1 IBA1	P55008
6	AIF1L	Allograft inflammatory factor 1-like	C9orf58 IBA2	Q9BQI0
7	ANKEF1	Ankyrin repeat and EF-hand domain-containing protein 1	ANKRD5	Q9NU02
8	CABP1	Calcium-binding protein 1		Q9NZU7
9	CABP2	Calcium-binding protein 2		Q9NPB3
10	CABP4	Calcium-binding protein 4		P57796
11	CABP5	Calcium-binding protein 5	CABP3	Q9NP86
12	CABP7	Calcium-binding protein 7	CALN2	Q86V35
13	CACNA1B	Voltage-dependent N-type calcium channel subunit alpha-1B	CACH5 CACNL1A5	Q00975
14	CACNA1E	Voltage-dependent R-type calcium channel subunit alpha-1E	CACH6 CACNL1A6	Q15878
15	CALB1	Calbindin	CAB27	P05937
16	CALB2	Calretinin	CAB29	P22676
17	CALM1	Calmodulin-1	CALM CAM CAM1	P0DP23
18	CALM2	Calmodulin-2	CAM2 CAMB	P0DP24
19	CALM3	Calmodulin-3	CALML2 CAM3 CAMC CAMIII	P0DP25
20	CALML3	Calmodulin-like protein 3		P27482
21	CALML4	Calmodulin-like protein 4		Q96GE6
22	CALML5	Calmodulin-like protein 5	CLSP	Q9NZT1
23	CALML6	Calmodulin-like protein 6	CAGLP CALGP	Q8TD86
24	CALN1	Calcium-binding protein 8	CABP8	Q9BXU9
25	CALU	Calumenin		O43852
26	CAPN1	Calpain-1 catalytic subunit	CANPL1	P07384
27	CAPN11	Calpain-11		Q9UMQ6
28	CAPN12	Calpain-12		Q6ZSI9
29	CAPN14	Calpain-14		A8MX76
30	CAPN2	Calpain-2 catalytic subunit	CANPL2	P17655
31	CAPN3	Calpain-3	CANP3 CANPL3 NCL1	P20807
32	CAPN8	Calpain-8	NCL2	A6NHC0
33	CAPN9	Calpain-9	NCL4	O14815
34	CAPNS1	Calpain small subunit 1	CAPN4 CAPNS	P04632
35	CAPNS2	Calpain small subunit 2		Q96L46
36	CAPS	Calcyphosin		Q13938
37	CAPS2	Calcyphosin-2		Q9BXY5
38	CAPSL	Calcyphosin-like protein		Q8WWF8
39	CETN1	Centrin-1	CEN1 CETN	Q12798
40	CETN2	Centrin-2	CALT CEN2	P41208
41	CETN3	Centrin-3	CEN3	O15182
42	CGREF1	Cell growth regulator with EF hand domain protein 1	CGR11	Q99674
43	CHP1	Calcineurin B homologous protein 1	CHP	Q99653
44	CHP2	Calcineurin B homologous protein 2	HCA520	O43745
45	CIB1	Calcium and integrin-binding protein 1	CIB KIP PRKDCIP	Q99828
46	CIB2	Calcium and integrin-binding family member 2	KIP2	O75838
47	CIB3	Calcium and integrin-binding family member 3	KIP3	Q96Q77
48	CIB4	Calcium and integrin-binding family member 4		A0PJX0
49	CRACR2A	EF-hand calcium-binding domain-containing protein 4B	EFCAB4B	Q9BSW2
50	CRACR2B	EF-hand calcium-binding domain-containing protein 4A	EFCAB4A	Q8N4Y2
51	CRNN	Cornulin	C1orf10 DRC1 PDRC1 SEP53	Q9UBG3
52	DGKA	Diacylglycerol kinase alpha	DAGK DAGK1	P23743
53	DGKB	Diacylglycerol kinase beta	DAGK2 KIAA0718	Q9Y6T7
54	DGKG	Diacylglycerol kinase gamma	DAGK3	P49619
55	DNAH7	Dynein heavy chain 7, axonemal	KIAA0944	Q8WXX0
56	DST	Dystonin	BP230 BP240 BPAG1 DMH DT KIAA0728	Q03001
57	DUOX1	Dual oxidase 1	DUOX LNOX1 THOX1	Q9NRD9
58	DUOX2	Dual oxidase 2	LNOX2 THOX2	Q9NRD8
59	EFCAB1	EF-hand calcium-binding domain-containing protein 1		Q9HAE3
60	EFCAB10	EF-hand calcium-binding domain-containing protein 10		A6NFE3
61	EFCAB11	EF-hand calcium-binding domain-containing protein 11	C14orf143	Q9BUY7
62	EFCAB12	EF-hand calcium-binding domain-containing protein 12	C3orf25	Q6NXP0
63	EFCAB14	EF-hand calcium-binding domain-containing protein 14	KIAA0494	O75071
64	EFCAB2	Dynein regulatory complex protein 8	DRC8	Q5VUJ9
65	EFCAB3	EF-hand calcium-binding domain-containing protein 3		Q8N7B9
66	EFCAB5	EF-hand calcium-binding domain-containing protein 5		A4FU69
67	EFCAB6	EF-hand calcium-binding domain-containing protein 6	DJBP KIAA1672	Q5THR3
68	EFCAB7	EF-hand calcium-binding domain-containing protein 7	KIAA1799	A8K855
69	EFCAB8	EF-hand calcium-binding domain-containing protein 8		A8MWE9
70	EFCAB9	EF-hand calcium-binding domain-containing protein 9		A8MZ26
71	EFCC1	EF-hand and coiled-coil domain-containing protein 1	C3orf73 CCDC48	Q9HA90
72	EFHB	EF-hand domain-containing family member B		Q8N7U6
73	EFHC1	EF-hand domain-containing protein 1		Q5JVL4
74	EFHC2	EF-hand domain-containing family member C2		Q5JST6
75	EFHD1	EF-hand domain-containing protein D1	SWS2	Q9BUP0
76	EFHD2	EF-hand domain-containing protein D2	SWS1	Q96C19
77	EHD1	EH domain-containing protein 1	PAST PAST1	Q9H4M9
78	EHD2	EH domain-containing protein 2	PAST2	Q9NZN4
79	EHD3	EH domain-containing protein 3	EHD2 PAST3	Q9NZN3
80	EHD4	EH domain-containing protein 4	HCA10 HCA11 PAST4	Q9H223
81	EPS15	Epidermal growth factor receptor substrate 15	AF1P	P42566
82	EPS15L1	Epidermal growth factor receptor substrate 15-like 1	EPS15R	Q9UBC2
83	FKBP10	Peptidyl-prolyl cis-trans isomerase FKBP10	FKBP65	Q96AY3
84	FKBP14	Peptidyl-prolyl cis-trans isomerase FKBP14	FKBP22	Q9NWM8
85	FKBP7	Peptidyl-prolyl cis-trans isomerase FKBP7	FKBP23	Q9Y680
86	FKBP9	Peptidyl-prolyl cis-trans isomerase FKBP9	FKBP60 FKBP63	O95302
87	FKBP9P1	Putative FK506-binding protein 9-like protein	FKBP9L	Q75LS8
88	FLG	Filaggrin		P20930
89	FLG2	Filaggrin-2	IFPS	Q5D862
90	FSTL1	Follistatin-related protein 1	FRP	Q12841
91	FSTL4	Follistatin-related protein 4	KIAA1061	Q6MZW2
92	FSTL5	Follistatin-related protein 5	KIAA1263	Q8N475
93	GCA	Grancalcin	GCL	P28676
94	GNPTAB	N-acetylglucosamine-1-phosphotransferase subunits alpha/beta	GNPTA KIAA1208	Q3T906
95	GPD2	Glycerol-3-phosphate dehydrogenase, mitochondrial		P43304
96	GUCA1A	Guanylyl cyclase-activating protein 1	C6orf131 GCAP GCAP1 GUCA1	P43080
97	GUCA1B	Guanylyl cyclase-activating protein 2	GCAP2	Q9UMX6
98	GUCA1C	Guanylyl cyclase-activating protein 3	GCAP3	O95843
99	HPCA	Neuron-specific calcium-binding protein hippocalcin	BDR2	P84074
100	HPCAL1	Hippocalcin-like protein 1	BDR1	P37235
101	HPCAL4	Hippocalcin-like protein 4		Q9UM19
102	HRNR	Hornerin	S100A18	Q86YZ3
103	ITSN1	Intersectin-1	ITSN SH3D1A	Q15811
104	ITSN2	Intersectin-2	KIAA1256 SH3D1B SWAP	Q9NZM3
105	KCNIP1	Kv channel-interacting protein 1	KCHIP1 VABP	Q9NZI2
106	KCNIP2	Kv channel-interacting protein 2	KCHIP2	Q9NS61
107	KCNIP3	Calsenilin	CSEN DREAM KCHIP3	Q9Y2W7
108	KCNIP4	Kv channel-interacting protein 4	CALP KCHIP4	Q6PIL6
109	LCP1	Plastin-2	PLS2	P13796
110	LETM1	Mitochondrial proton/calcium exchanger protein		O95202
111	LPCAT1	Lysophosphatidylcholine acyltransferase 1	AYTL2 PFAAP3	Q8NF37
112	LPCAT2	Lysophosphatidylcholine acyltransferase 2	AGPAT11 AYTL1	Q7L5N7
113	MACF1	Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5	ABP620 ACF7 KIAA0465 KIAA1251	Q9UPN3
114	MCFD2	Multiple coagulation factor deficiency protein 2	SDNSF	Q8NI22
115	MICU1	Calcium uptake protein 1, mitochondrial	CALC CBARA1	Q9BPX6
116	MICU2	Calcium uptake protein 2, mitochondrial	EFHA1	Q8IYU8
117	MICU3	Calcium uptake protein 3, mitochondrial	EFHA2	Q86XE3
118	MYL1	Myosin light chain 1/3, skeletal muscle isoform		P05976
119	MYL10	Myosin regulatory light chain 10	MYLC2PL PLRLC	Q9BUA6
120	MYL12A	Myosin regulatory light chain 12A	MLCB MRLC3 RLC	P19105
121	MYL12B	Myosin regulatory light chain 12B	MRLC2 MYLC2B	O14950
122	MYL2	Myosin regulatory light chain 2, ventricular/cardiac muscle isoform	MLC2	P10916
123	MYL3	Myosin light chain 3		P08590
124	MYL4	Myosin light chain 4	MLC1	P12829
125	MYL5	Myosin light chain 5		Q02045
126	MYL6	Myosin light polypeptide 6		P60660
127	MYL6B	Myosin light chain 6B	MLC1SA	P14649
128	MYL7	Myosin regulatory light chain 2, atrial isoform	MYL2A MYLC2A	Q01449
129	MYL9	Myosin regulatory light polypeptide 9	MLC2 MRLC1 MYRL2	P24844
130	MYLPF	Myosin regulatory light chain 2, skeletal muscle isoform		Q96A32
131	NCALD	Neurocalcin-delta		P61601
132	NCS1	Neuronal calcium sensor 1	FLUP FREQ	P62166
133	NECAB1	N-terminal EF-hand calcium-binding protein 1	EFCBP1	Q8N987
134	NECAB2	N-terminal EF-hand calcium-binding protein 2	EFCBP2	Q7Z6G3
135	NECAB3	N-terminal EF-hand calcium-binding protein 3	APBA2BP NIP1 SYTIP2 XB51	Q96P71
136	NIN	Ninein	KIAA1565	Q8N4C6
137	NINL	Ninein-like protein	KIAA0980 NLP	Q9Y2I6
138	NKD1	Protein naked cuticle homolog 1	NKD	Q969G9
139	NKD2	Protein naked cuticle homolog 2		Q969F2
140	NOX5	NADPH oxidase 5		Q96PH1
141	NUCB1	Nucleobindin-1	NUC	Q02818
142	NUCB2	Nucleobindin-2	NEFA	P80303
143	OCM	Oncomodulin-1	OCM1 OCMN	P0CE72
144	OCM2	Putative oncomodulin-2	OCMN	P0CE71
145	P4HTM	Transmembrane prolyl 4-hydroxylase	PH4	Q9NXG6
146	PDCD6	Programmed cell death protein 6	ALG2	O75340
147	PEF1	Peflin	ABP32	Q9UBV8
148	PKD2	Polycystin-2	TRPP2	Q13563
149	PLCD1	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1		P51178
150	PLCD4	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4		Q9BRC7
151	PLCG1	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1	PLC1	P19174
152	PLCH1	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-1	KIAA1069 PLCL3	Q4KWH8
153	PLCH2	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-2	KIAA0450 PLCL4	O75038
154	PLCZ1	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase zeta-1		Q86YW0
155	PLS1	Plastin-1		Q14651
156	PLS3	Plastin-3		P13797
157	PPEF1	Serine/threonine-protein phosphatase with EF-hands 1	PPEF PPP7C	O14829
158	PPEF2	Serine/threonine-protein phosphatase with EF-hands 2		O14830
159	PPP2R3A	Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit alpha	PPP2R3	Q06190
160	PPP2R3B	Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit beta	PPP2R3L	Q9Y5P8
161	PPP3R1	Calcineurin subunit B type 1	CNA2 CNB	P63098
162	PPP3R2	Calcineurin subunit B type 2	CBLP PPP3RL	Q96LZ3
163	PRKCSH	Glucosidase 2 subunit beta	G19P1	P14314
164	PVALB	Parvalbumin alpha		P20472
165	PVALEF	Parvalbumin-like EF-hand-containing protein		A0A1B0GWK0
166	RAB11FIP3	Rab11 family-interacting protein 3	ARFO1 KIAA0665	O75154
167	RAB11FIP4	Rab11 family-interacting protein 4	ARFO2 KIAA1821	Q86YS3
168	RAB44	Ras-related protein Rab-44		Q7Z6P3
169	RASEF	Ras and EF-hand domain-containing protein	RAB45	Q8IZ41
170	RASGRP1	RAS guanyl-releasing protein 1	RASGRP	O95267
171	RASGRP2	RAS guanyl-releasing protein 2	CDC25L MCG7	Q7LDG7
172	RASGRP3	Ras guanyl-releasing protein 3	GRP3 KIAA0846	Q8IV61
173	RASGRP4	RAS guanyl-releasing protein 4		Q8TDF6
174	RCN1	Reticulocalbin-1	RCN	Q15293
175	RCN2	Reticulocalbin-2	ERC55	Q14257
176	RCN3	Reticulocalbin-3		Q96D15
177	RCVRN	Recoverin	RCV1	P35243
178	REPS1	RalBP1-associated Eps domain-containing protein 1		Q96D71
179	REPS2	RalBP1-associated Eps domain-containing protein 2	POB1	Q8NFH8
180	RHBDL3	Rhomboid-related protein 3	RHBDL4 VRHO	P58872
181	RHOT1	Mitochondrial Rho GTPase 1	ARHT1	Q8IXI2
182	RHOT2	Mitochondrial Rho GTPase 2	ARHT2 C16orf39	Q8IXI1
183	RPTN	Repetin		Q6XPR3
184	RYR1	Ryanodine receptor 1	RYDR	P21817
185	RYR2	Ryanodine receptor 2		Q92736
186	RYR3	Ryanodine receptor 3	HBRR	Q15413
187	S100A1	Protein S100-A1	S100A	P23297
188	S100A11	Protein S100-A11	MLN70 S100C	P31949
189	S100A12	Protein S100-A12		P80511
190	S100A16	Protein S100-A16	S100F	Q96FQ6
191	S100A2	Protein S100-A2	S100L	P29034
192	S100A4	Protein S100-A4	CAPL MTS1	P26447
193	S100A5	Protein S100-A5	S100D	P33763
194	S100A6	Protein S100-A6	CACY	P06703
195	S100A7	Protein S100-A7	PSOR1 S100A7C	P31151
196	S100A7A	Protein S100-A7A	S100A15 S100A7L1	Q86SG5
197	S100A7L2	Protein S100-A7-like 2	S100A7B	Q5SY68
198	S100A8	Protein S100-A8	CAGA CFAG MRP8	P05109
199	S100A9	Protein S100-A9	CAGB CFAG MRP14	P06702
200	S100B	Protein S100-B		P04271
201	S100G	Protein S100-G	CABP9K CALB3 S100D	P29377
202	S100P	Protein S100-P	S100E	P25815
203	S100Z	Protein S100-Z		Q8WXG8
204	SCGN	Secretagogin	SECRET	O76038
205	SDF4	45 kDa calcium-binding protein	CAB45	Q9BRK5
206	SELENON	Selenoprotein N	SELN SEPN1	Q9NZV5
207	SLC25A12	Calcium-binding mitochondrial carrier protein Aralar1	ARALAR1	O75746
208	SLC25A13	Calcium-binding mitochondrial carrier protein Aralar2	ARALAR2	Q9UJS0
209	SLC25A23	Calcium-binding mitochondrial carrier protein SCaMC-3	APC2 MCSC2 SCAMC3	Q9BV35
210	SLC25A24	Calcium-binding mitochondrial carrier protein SCaMC-1	APC1 MCSC1 SCAMC1	Q6NUK1
211	SLC25A25	Calcium-binding mitochondrial carrier protein SCaMC-2	APC3 KIAA1896 MCSC3 SCAMC2	Q6KCM7
212	SMOC2	SPARC-related modular calcium-binding protein 2	SMAP2	Q9H3U7
213	SPARCL1	SPARC-like protein 1		Q14515
214	SPATA21	Spermatogenesis-associated protein 21		Q7Z572
215	SPTA1	Spectrin alpha chain, erythrocytic 1	SPTA	P02549
216	SPTAN1	Spectrin alpha chain, non-erythrocytic 1	NEAS SPTA2	Q13813
217	SRI	Sorcin		P30626
218	SWAP70	Switch-associated protein 70	KIAA0640	Q9UH65
219	TBC1D8B	TBC1 domain family member 8B		Q0IIM8
220	TBC1D9	TBC1 domain family member 9	KIAA0882 TBC1D9A	Q6ZT07
221	TBC1D9B	TBC1 domain family member 9B	KIAA0676	Q66K14
222	TCHH	Trichohyalin	THH THL TRHY	Q07283
223	TESC	Calcineurin B homologous protein 3	CHP3	Q96BS2
224	TNNC1	Troponin C, slow skeletal and cardiac muscles	TNNC	P63316
225	TNNC2	Troponin C, skeletal muscle		P02585
226	USP32	Ubiquitin carboxyl-terminal hydrolase 32	USP10	Q8NFA0
227	VSNL1	Visinin-like protein 1	VISL1	P62760
228	ZZEF1	Zinc finger ZZ-type and EF-hand domain-containing protein 1	KIAA0399	O43149