The Ligandable Human Proteome

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G protein-coupled receptor, rhodopsin-like

IndexGene NameProtein NameDrugsPDB Code
15HT2A5-hydroxytryptamine receptor 2AZotepine,Cholesterol6a94, 6a93
2PAR1Proteinase-activated receptor 1Vorapaxar3vw7
3PE2R3Prostaglandin E2 receptor EP3 subtypeDinoprostone,Alprostadil6ak3
4CCR5C-C chemokine receptor type 5Maraviroc4mbs
5ADRB2Beta-2 adrenergic receptorSalmeterol,Timolol6mxt, 3d4s
6MTR1AMelatonin receptor type 1ARamelteon6me2
7NK1RSubstance-P receptorNetupitant6hlp
85HT2B5-hydroxytryptamine receptor 2BErgotamine,Methylergometrine,Ergometrine4ib4, 5tud, 4nc3, 6dry
95HT1B5-hydroxytryptamine receptor 1BErgotamine,Dihydroergotamine4iar, 4iaq
105HT2C5-hydroxytryptamine receptor 2CErgotamine6bqg
11P2Y12P2Y purinoceptor 12Cholesterol4pxz, 4ntj
12CNR1Cannabinoid receptor 1Cholesterol5xra, 5xr8, 6n4b
13OPRMMu-type opioid receptorCholesterol5c1m, 4dkl
14CCR9C-C chemokine receptor type 9Cholesterol5lwe
15P2RY1P2Y purinoceptor 1Cholesterol4xnv
16TA2RThromboxane A2 receptorCholesterol6iiv, 6iiu
17AA2ARAdenosine receptor A2aCholesterol5nlx
18ACM2Muscarinic acetylcholine receptor M2Methscopolamine bromide, Scopolamine, Methscopolamine5yc8, 5zk8, 5zkc
19AGTR1Type-1 angiotensin II receptorOlmesartan4zud
20ACM3Muscarinic acetylcholine receptor M3Tiotropium4u15
21ACM4Muscarinic acetylcholine receptor M4Tiotropium5dsg
22ACM1Muscarinic acetylcholine receptor M1Tiotropium5cxv