The Ligandable Human Proteome

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GHMP kinase N-terminal domain

NumberGene NameProtein NamePrimary TissueMedian Essentiality ScoreNumber of Cell Lines
1MVKMevalonate kinaseTHYROID-1.0393
1MVKMevalonate kinasePLEURA-1.1617
1MVKMevalonate kinaseLIVER-1.14316
1MVKMevalonate kinaseENDOMETRIUM-1.38716
1MVKMevalonate kinaseGANGLIA-1.26518
1MVKMevalonate kinaseSTOMACH-1.25920
1MVKMevalonate kinaseKIDNEY-1.32820
1MVKMevalonate kinaseBONE-1.14823
1MVKMevalonate kinaseOESOPHAGUS-1.19524
1MVKMevalonate kinaseINTESTINE-1.2425
1MVKMevalonate kinasePANCREAS-1.30526
1MVKMevalonate kinaseBREAST-1.328
1MVKMevalonate kinaseSOFT_TISSUE-1.35831
1MVKMevalonate kinaseOVARY-1.28636
1MVKMevalonate kinaseSKIN-1.336
1MVKMevalonate kinaseTRACT-1.19753
1MVKMevalonate kinaseHAEMATOPOIETIC_AND_LYMPHOID_TISSUE-1.36458
1MVKMevalonate kinaseLUNG-1.30373
2MVDDiphosphomevalonate decarboxylaseGANGLIA-1.15618
2MVDDiphosphomevalonate decarboxylaseKIDNEY-1.0220
2MVDDiphosphomevalonate decarboxylaseINTESTINE-1.03525
2MVDDiphosphomevalonate decarboxylasePANCREAS-1.13526
2MVDDiphosphomevalonate decarboxylaseBREAST-1.02628
2MVDDiphosphomevalonate decarboxylaseSOFT_TISSUE-1.03131
2MVDDiphosphomevalonate decarboxylaseSKIN-1.12636
2MVDDiphosphomevalonate decarboxylaseHAEMATOPOIETIC_AND_LYMPHOID_TISSUE-1.0458
2MVDDiphosphomevalonate decarboxylaseLUNG-1.01573