| Number | Gene Name | Protein Name | Primary Tissue | Median Essentiality Score | Number of Cell Lines |
| 1 | VCP | Transitional endoplasmic reticulum ATPase | THYROID | -1.557 | 3 |
| 1 | VCP | Transitional endoplasmic reticulum ATPase | CERVIX | -1.705 | 3 |
| 1 | VCP | Transitional endoplasmic reticulum ATPase | PLEURA | -1.668 | 7 |
| 1 | VCP | Transitional endoplasmic reticulum ATPase | ENDOMETRIUM | -1.743 | 16 |
| 1 | VCP | Transitional endoplasmic reticulum ATPase | LIVER | -1.842 | 16 |
| 1 | VCP | Transitional endoplasmic reticulum ATPase | GANGLIA | -1.674 | 18 |
| 1 | VCP | Transitional endoplasmic reticulum ATPase | STOMACH | -1.833 | 20 |
| 1 | VCP | Transitional endoplasmic reticulum ATPase | KIDNEY | -1.854 | 20 |
| 1 | VCP | Transitional endoplasmic reticulum ATPase | BONE | -1.717 | 23 |
| 1 | VCP | Transitional endoplasmic reticulum ATPase | OESOPHAGUS | -1.688 | 24 |
| 1 | VCP | Transitional endoplasmic reticulum ATPase | INTESTINE | -1.769 | 25 |
| 1 | VCP | Transitional endoplasmic reticulum ATPase | PANCREAS | -1.681 | 26 |
| 1 | VCP | Transitional endoplasmic reticulum ATPase | BREAST | -1.816 | 28 |
| 1 | VCP | Transitional endoplasmic reticulum ATPase | SOFT_TISSUE | -1.746 | 31 |
| 1 | VCP | Transitional endoplasmic reticulum ATPase | SKIN | -1.788 | 36 |
| 1 | VCP | Transitional endoplasmic reticulum ATPase | OVARY | -1.806 | 36 |
| 1 | VCP | Transitional endoplasmic reticulum ATPase | SYSTEM | -1.804 | 44 |
| 1 | VCP | Transitional endoplasmic reticulum ATPase | TRACT | -1.666 | 53 |
| 1 | VCP | Transitional endoplasmic reticulum ATPase | HAEMATOPOIETIC_AND_LYMPHOID_TISSUE | -1.865 | 58 |
| 1 | VCP | Transitional endoplasmic reticulum ATPase | LUNG | -1.701 | 73 |