| Number | Gene Name | Protein Name | Primary Tissue | Median Essentiality Score | Number of Cell Lines |
| 1 | SOD1 | Superoxide dismutase [Cu-Zn] | Skin | -3.275 | 4 |
| 1 | SOD1 | Superoxide dismutase [Cu-Zn] | Bone | -2.832 | 12 |
| 1 | SOD1 | Superoxide dismutase [Cu-Zn] | Head and Neck | -2.725 | 34 |
| 1 | SOD1 | Superoxide dismutase [Cu-Zn] | Kidney | -2.352 | 3 |
| 1 | SOD1 | Superoxide dismutase [Cu-Zn] | Large Intestine | -1.877 | 30 |
| 1 | SOD1 | Superoxide dismutase [Cu-Zn] | Central Nervous System | -1.832 | 33 |
| 1 | SOD1 | Superoxide dismutase [Cu-Zn] | Esophagus | -1.828 | 26 |
| 1 | SOD1 | Superoxide dismutase [Cu-Zn] | Endometrium | -1.764 | 8 |
| 1 | SOD1 | Superoxide dismutase [Cu-Zn] | Stomach | -1.708 | 14 |
| 1 | SOD1 | Superoxide dismutase [Cu-Zn] | Breast | -1.701 | 25 |
| 1 | SOD1 | Superoxide dismutase [Cu-Zn] | Pancreas | -1.685 | 23 |
| 1 | SOD1 | Superoxide dismutase [Cu-Zn] | Prostate | -1.53 | 3 |
| 1 | SOD1 | Superoxide dismutase [Cu-Zn] | Ovary | -1.48 | 31 |
| 1 | SOD1 | Superoxide dismutase [Cu-Zn] | Haematopoietic and Lymphoid | -1.466 | 14 |
| 1 | SOD1 | Superoxide dismutase [Cu-Zn] | Lung | -1.366 | 42 |