| Number | Gene Name | Protein Name | Primary Tissue | Median Essentiality Score | Number of Cell Lines |
| 1 | PGAM4 | Probable phosphoglycerate mutase 4 | Skin | -2.161 | 4 |
| 1 | PGAM4 | Probable phosphoglycerate mutase 4 | Endometrium | -2.1 | 8 |
| 1 | PGAM4 | Probable phosphoglycerate mutase 4 | Head and Neck | -1.95 | 34 |
| 1 | PGAM4 | Probable phosphoglycerate mutase 4 | Lung | -1.934 | 42 |
| 1 | PGAM4 | Probable phosphoglycerate mutase 4 | Bone | -1.92 | 12 |
| 1 | PGAM4 | Probable phosphoglycerate mutase 4 | Kidney | -1.817 | 3 |
| 1 | PGAM4 | Probable phosphoglycerate mutase 4 | Peripheral Nervous System | -1.813 | 17 |
| 1 | PGAM4 | Probable phosphoglycerate mutase 4 | Large Intestine | -1.775 | 30 |
| 1 | PGAM4 | Probable phosphoglycerate mutase 4 | Central Nervous System | -1.719 | 33 |
| 1 | PGAM4 | Probable phosphoglycerate mutase 4 | Esophagus | -1.702 | 26 |
| 1 | PGAM4 | Probable phosphoglycerate mutase 4 | Haematopoietic and Lymphoid | -1.692 | 14 |
| 1 | PGAM4 | Probable phosphoglycerate mutase 4 | Prostate | -1.635 | 3 |
| 1 | PGAM4 | Probable phosphoglycerate mutase 4 | Breast | -1.538 | 25 |
| 1 | PGAM4 | Probable phosphoglycerate mutase 4 | Stomach | -1.368 | 14 |
| 1 | PGAM4 | Probable phosphoglycerate mutase 4 | Ovary | -1.359 | 31 |
| 1 | PGAM4 | Probable phosphoglycerate mutase 4 | Pancreas | -1.208 | 23 |
| 2 | PGAM1 | Phosphoglycerate mutase 1 | Bone | -1.754 | 12 |
| 2 | PGAM1 | Phosphoglycerate mutase 1 | Haematopoietic and Lymphoid | -1.189 | 14 |
| 2 | PGAM1 | Phosphoglycerate mutase 1 | Skin | -1.092 | 4 |