Index | Ligand Name | Structure | PDB code | ligand desolvation |
1 | 324 | Crystal structure of a BRAF kinase domain monomer | 4wo5 | 97.3 |
2 | 1oo | B-Raf Kinase domain in complex with PLX5568 | 4xv9 | 94.16 |
3 | 6dc | Crystal Structure of BRAF Kinase Domain Bound to AZ-VEM | 5ita | 93.31 |
4 | p06 | BRAF Kinase domain b3aC loop deletion mutant in complex with dabrafenib | 5hie | 93.13 |
5 | 4z5 | CRYSTAL STRUCTURE OF BRAF(V600E) IN COMPLEX WITH LY3009120 COMPND | 5c9c | 92.35 |
6 | 6n9 | BRAFV600E Kinase Domain In Complex with Chemically Linked Vemurafenib Inhibitor VEM-6-VEM | 5jrq | 91.41 |
7 | 8en | Crystals Structure of B-Raf kinase domain in complex with an Imidazopyridinyl benzamide inhibitor | 6b8u | 91.27 |
8 | l1e | B-Raf V600E kinase domain in complex with an aminoisoquinoline inhibitor | 3idp | 91.24 |
9 | 5xj | B-Raf wild-type kinase domain in complex with a purinylpyridinylamino-based inhibitor | 5fd2 | 91.05 |
10 | 92j | BRAF in Complex with RAF709 | 5vam | 90.99 |
11 | bax | The complex of wild type B-RAF and BAY439006. | 1uwh | 90.75 |
12 | 032 | Crystal structure of the BRAF (R509H) kinase domain monomer bound to Vemurafenib | 4rzv | 90.65 |
13 | p06 | B-RAF in complex with Dabrafenib | 5csw | 90.33 |
14 | p06 | B-Raf Kinase V600E oncogenic mutant in complex with Dabrafenib | 4xv2 | 90.29 |
15 | k81 | BRAF in complex with N-(3-(2-(2-hydroxyethoxy)-6-morpholinopyridin-4-yl)-4-methylphenyl)-2-(trifluoromethyl)isonicotinamide (LXH254) | 6n0p | 89.65 |
16 | b1e | BRAF Kinase domain b3aC loop deletion mutant in complex with AZ628 | 5hid | 89.23 |
17 | 29l | BRAF dimer bound to 14-3-3 | 6u2h | 89.01 |
18 | 324 | B-Raf Kinase in Complex with PLX4720 | 3c4c | 88.96 |
19 | bax | BRAF Kinase domain b3aC loop deletion mutant in complex with sorafenib | 5hi2 | 88.91 |
20 | p02 | B-Raf Kinase V600E oncogenic mutant in complex with PLX7922 | 4xv3 | 88.12 |
21 | 29l | Crystal structure of BRAF-V600E bound to GDC0879 | 4mnf | 87.18 |
22 | 0t2 | Crystal Structure of Human Kinase Domain of B-raf with a DFG-out Inhibitor | 4fc0 | 86.17 |
23 | 1su | Crystal Structure of Human B-raf bound to a DFG-out Inhibitor TAK-632 | 4ksp | 85.91 |
24 | 325 | B-Raf Kinase V600E Oncogenic Mutant in Complex with PLX3203 | 4fk3 | 85.51 |
25 | fp3 | Crystal Structure of Human B-Raf Kinase Domain in Complex with a Non-Oxime Furopyridine Inhibitor | 3prf | 84.23 |
26 | 032 | B-Raf Kinase V600E oncogenic mutant in complex with PLX4032 | 3og7 | 84.1 |
27 | fni | Human B-Raf Kinase in Complex with a Non-Oxime Furopyridine Inhibitor | 3ppk | 82.45 |
28 | 904 | B-Raf Kinase V600E oncogenic mutant in complex with PLX7904 | 4xv1 | 81.61 |
29 | sm5 | Pyrazole-based inhibitors of B-Raf kinase | 3d4q | 81.51 |
30 | 54j | CRYSTAL STRUCTURE OF B-RAF IN COMPLEX WITH BI 882370 | 5csx | 79.7 |
31 | 831 | The Complex of wild-type B-RAF with Pyrazolo pyrimidine inhibitor | 3ii5 | 73.87 |
32 | 734 | BRAF in complex with an organic inhibitor 7898734 | 4e26 | 70.76 |
33 | 215 | Structure of the B-Raf kinase domain bound to SB-590885 | 2fb8 | 67.65 |