Index | Ligand Name | Structure | PDB code | ligand desolvation |
1 | 0li | Crystal Structure of the Tyrosine Kinase Domain of FGF Receptor 4 in Complex with Ponatinib | 4qrc | 92.68 |
2 | 9ct | FIBROBLAST GROWTH FACTOR RECEPTOR 4 KINASE DOMAIN (449-753) IN COMPLEX WITH IRREVERSIBLE LIGAND CGA159527 | 5nwz | 89.93 |
3 | 0li | FGFR4 in complex with Ponatinib | 4uxq | 89.18 |
4 | 0li | Structural analysis of the human Fibroblast Growth Factor Receptor 4 Kinase | 4tyj | 87.39 |
5 | xl5 | FGFR4 complex with N-(2-((5-((2,6-dichloro-3,5-dimethoxybenzyl)oxy)pyrimidin-2-yl)amino)-3-fluorophenyl)acrylamide | 6nvj | 83.41 |
6 | xl9 | FGFR4 complex with BLU-554, N-((3S,4S)-3-((6-(2,6-dichloro-3,5-dimethoxyphenyl)quinazolin-2-yl)amino)tetrahydro-2H-pyran-4-yl)acrylamide | 6nvk | 82.83 |
7 | xl6 | FGFR4 complex with N-(2-((5-((2,6-dichloro-3,5-dimethoxybenzyl)oxy)pyrimidin-2-yl)amino)-3-methylphenyl)acrylamide | 6nvh | 82.48 |
8 | 40m | Crystal Structure of FGFR4 with an Irreversible Inhibitor | 4xcu | 81.74 |
9 | xl7 | FGFR4 complex with N-(3-chloro-2-((5-((2,6-dichloro-3,5-dimethoxybenzyl)oxy)pyrimidin-2-yl)amino)-5-fluorophenyl)acrylamide | 6nvi | 80.89 |
10 | 6lf | The crystal structure of FGFR4 kinase domain in complex with LY2874455 | 5jkg | 79.6 |
11 | xl8 | FGFR4 complex with N-(3,5-dichloro-2-((5-((2,6-dichloro-3,5-dimethoxybenzyl)oxy)pyrimidin-2-yl)amino)phenyl)acrylamide | 6nvg | 79.44 |
12 | 6lf | Crystal structure of LY2874455 in complex of FGFR4 gatekeeper mutation (V550L) | 5xff | 75.48 |
13 | fgf | Crystal structure of FGF401 in complex of FGFR4 | 6jpj | 67.49 |