| Index | Ligand Name | Structure | PDB code | ligand desolvation |
| 1 | ir1 | Crystal structure of insulin receptor kinase domain in complex with an inhibitor Irfin-1 | 4ibm | 88.98 |
| 2 | 60o | Crystal structure of insulin receptor kinase domain in complex with cis-(R)-7-(3-(azetidin-1-ylmethyl)cyclobutyl)-5-(3-((tetrahydro-2H-pyran-2-yl)methoxy)phenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine. | 5hhw | 86.17 |
| 3 | 351 | Kinase domain of insulin receptor complexed with a pyrrolo pyridine inhibitor | 3eta | 84.56 |
| 4 | 5ja | The Crystal structure of INSR Tyrosine Kinase in complex with the Inhibitor BI 885578 | 5e1s | 70.9 |
| 5 | gs2 | Insulin receptor kinase complexed with an inhibitor | 3ekk | 70.44 |
| 6 | gs3 | Insulin receptor kinase complexed with an inhibitor | 3ekn | 68.24 |