| Index | Ligand Name | Structure | PDB code | ligand desolvation |
| 1 | 5fi | Crystal structures of human p70S6K1-T389E | 4l45 | 94.16 |
| 2 | 5fi | Crystal structures of human p70S6K1-T389A (form I) | 4l43 | 92.72 |
| 3 | 5fi | Crystal structures of human p70S6K1-T389A (form II) | 4l44 | 91.01 |
| 4 | 5fi | Crystal structures of human p70S6K1 kinase domain (Zinc anomalous) | 4l3l | 89.6 |
| 5 | 5fi | Crystal structures of human p70S6K1 kinase domain | 4l3j | 88.86 |
| 6 | 5fi | Crystal structures of human p70S6K1-PIF | 4l42 | 88.43 |
| 7 | 5fi | Crystal structure of S6K1 kinase domain in complex with a pyrimidine derivative PF-4708671 2-{[4-(5-ethylpyrimidin-4-yl)piperazin-1-yl]methyl}-5-(trifluoromethyl)-1H-benzimidazole | 3we4 | 88.18 |
| 8 | fs9 | Crystal structure of S6K1 kinase domain in complex with a purine derivative 1-(9H-purin-6-yl)-N-[3-(trifluoromethyl)phenyl]piperidine-4-carboxamide | 3wf7 | 87.39 |
| 9 | fz8 | Crystal structure of S6K1 kinase domain in complex with a pyrazolopyrimidine derivative 4-[4-(1H-benzimidazol-2-yl)piperidin-1-yl]-1H-pyrazolo[3,4-d]pyrimidine | 3wf5 | 87.18 |
| 10 | fs7 | Crystal structure of S6K1 kinase domain in complex with a quinoline derivative 1-oxo-1-[(4-sulfamoylphenyl)amino]propan-2-yl-2-methyl-1,2,3,4-tetrahydroacridine-9-carboxylate | 3wf9 | 86.68 |
| 11 | f76 | Crystal structure of S6K1 kinase domain in complex with a quinoline derivative 2-oxo-2-[(4-sulfamoylphenyl)amino]ethyl 7,8,9,10-tetrahydro-6H-cyclohepta[b]quinoline-11-carboxylate | 3wf8 | 86.56 |