| Index | Ligand Name | Structure | PDB code | ligand desolvation |
| 1 | ieo | Crystal Structures of Ask1-inhibitor Complexes | 4bib | 89.88 |
| 2 | ie8 | Crystal Structures of Ask1-inhibitor Complexes | 4bid | 89.7 |
| 3 | 9e1 | Crystal structure of ASK1 kinase domain with a potent inhibitor (analog 6) | 5vil | 88.71 |
| 4 | 8v7 | Structure-based drug design of novel ASK1 inhibitors using a fully integrated lead optimization strategy | 5v24 | 88.35 |
| 5 | 8gs | Structure-Based Design of ASK1 Inhibitors as Potential First-in-Class Agents for Heart Failure | 5up3 | 88.19 |
| 6 | ie6 | Crystal Structures of Ask1-inhibitor Complexes | 4bie | 86.95 |
| 7 | kk7 | ASK1 kinase domain complex with inhibitor | 6e2m | 86.52 |
| 8 | 9e4 | Crystal structure of ASK1 kinase domain with a potent inhibitor (analog 13) | 5vio | 84.47 |
| 9 | kk8 | ASK1 kinase domain complex with inhibitor | 6e2n | 81.85 |
| 10 | 8gy | Structure-Based Design of ASK1 Inhibitors as Potential First-in-Class Agents for Heart Failure | 5uox | 80.36 |
| 11 | 8gv | Structure-Based Design of ASK1 Inhibitors as Potential First-in-Class Agents for Heart Failure | 5uor | 78.92 |
| 12 | im6 | Crystal structure of human apoptosis signal-regulating kinase 1 (ASK1) with imidazopyridine inhibitor | 3vw6 | 72.75 |
| 13 | bh9 | Crystal Structures of Ask1-inhibitor Complexes | 4bhn | 70.38 |