Index | Ligand Name | Structure | PDB code | ligand desolvation |
1 | 79y | Structure-based optimization of 1H-imidazole-2-carboxamides as Axl kinase inhibitors utilizing a Mer mutant surrogate | 5tc0 | 85.38 |
2 | 24k | Crystal structure of the catalytic domain of the proto-oncogene tyrosine-protein kinase MER in complex with inhibitor UNC1917 | 4m3q | 81.08 |
3 | 7ys | Crystal structure of the Mer kinase domain in complex with a macrocyclic inhibitor | 5u6c | 80.42 |
4 | mh7 | Crystal structure of the catalytic domain of the proto-oncogene tyrosine-protein kinase MER in complex with inhibitor UNC1896 | 4mh7 | 78.62 |
5 | 7ae | Structure-based optimization of 1H-imidazole-2-carboxamides as Axl kinase inhibitors utilizing a Mer mutant surrogate | 5td2 | 75.97 |
6 | olp | Crystal structure of catalytic domain of the proto-oncogene tyrosine-protein kinase MER in complex with inhibitor C52 | 3bpr | 73.1 |
7 | ckj | Crystal structure of the catalytic domain of the proto-oncogene tyrosine-protein kinase MER in complex with inhibitor UNC569 | 3tcp | 72.33 |
8 | k0x | Crystal structure of the catalytic domain of the proto-oncogene tyrosine-protein kinase MER in complex with inhibitor UNC2541 | 5k0x | 70.45 |
9 | 4mh | Crystal structure of the catalytic domain of the proto-oncogene tyrosine-protein kinase MER in complex with inhibitor UNC1817 | 4mha | 67.45 |
10 | 6q1 | Crystal structure of the catalytic domain of the proto-oncogene tyrosine-protein kinase MER in complex with inhibitor UNC2434 | 5k0k | 65.05 |