| Index | Ligand Name | Structure | PDB code | ligand desolvation |
| 1 | l8v | Crystal structure of the tyrosine kinase domain of the hepatocyte growth factor receptor C-MET in complex with a biarylamine based inhibitor | 3l8v | 96.12 |
| 2 | 319 | Crystal structure of the tyrosine kinase domain of the hepatocyte growth factor receptor c-met in complex with a aminopyridine based inhibitor | 3cth | 95.76 |
| 3 | 353 | Crystal structure of the tyrosine kinase domain of the hepatocyte growth factor receptor C-MET in complex with N-(4-(2-amino-3-chloropyridin-4-yloxy)-3-fluorophenyl)-4-ethoxy-1-(4-fluorophenyl)-2-oxo-1,2-dihydropyridine-3-carboxamide | 3f82 | 94.65 |
| 4 | dwf | Crystal structure of CMET in complex with novel inhibitor | 4mxc | 92.99 |
| 5 | mt3 | Structure of c-Met with pyrimidone inhibitor 7 | 3efj | 92.79 |
| 6 | 5b4 | CRYSTAL STRUCTURE OF THE TYROSINE KINASE DOMAIN OF THE HEPATOCYTE GROWTH FACTOR RECEPTOR C-MET IN COMPLEX WITH ALTIRATINIB ANALOG DP-4157 | 5dg5 | 92.64 |
| 7 | 353 | Crystal structure of D1228V cMET bound by BMS-777607 | 6sdd | 92.63 |
| 8 | 6xp | Crystal structure of C-MET kinase domain in complex with N'-((3Z)-4- chloro-7-methyl-2-oxo-1,2-dihydro-3H-indol-3-ylidene)-2-(4- hydroxyphenyl)propanohydrazide | 3zze | 92.62 |
| 9 | df6 | Crystal structure of human c-Met kinase domain with its inhibitor | 3vw8 | 92.09 |
| 10 | 044 | Crystal structure of c-Met in complex with pyrazolone inhibitor 58a | 3u6i | 91.72 |
| 11 | 5tf | X-ray Structure of c-Met kinase in complex with inhibitor (S)-3-(1-(1H-pyrrolo(2,3-b)pyridin-3-yl)ethyl)-N-isopropyl-(1,2,4)triazolo(4,3- b)pyridazin-6-amine | 3zcl | 91.47 |
| 12 | 1fn | Crystal structure of the tyrosine kinase domain of the hepatocyte growth factor receptor C-MET in complex with a Pyrrolopyridinepyridone based inhibitor | 3ce3 | 91.17 |
| 13 | w9z | X-ray Structure of c-Met kinase in complex with inhibitor (S)-6-(1-(6- (1-methyl-1H-pyrazol-4-yl)-(1,2,4)triazolo(4,3-b)pyridazin-3-yl)ethyl) quinoline. | 3zc5 | 91.14 |
| 14 | mt4 | Structure of c-Met with pyrimidone inhibitor 50 | 3efk | 91 |
| 15 | lkg | X-ray structure of c-Met with triazolopyridazine inhibitor. | 3ccn | 90.9 |
| 16 | 320 | Crystal structure of the tyrosine kinase domain of the hepatocyte growth factor receptor c-met in complex with a aminopyridine based inhibitor | 3ctj | 90.87 |
| 17 | 03x | Crystal structure of c-Met in complex with pyrazolone inhibitor 26 | 3u6h | 90.74 |
| 18 | 5sz | Crystal structure of c-Met in complex with naphthyridinone inhibitor 5 | 5eyc | 90.63 |
| 19 | f47 | Crystal structure of C-MET kinase domain in complex with 4-((6-(4- fluorophenyl)-(1,2,4)triazolo(4,3-b)(1,2,4)triazin-3-yl)methyl)phenol | 4ap7 | 90.5 |
| 20 | 3qt | c-Met Kinase in Complex with NVP-BVU972 | 3qti | 90.43 |
| 21 | l5g | X-ray Structure of c-Met with triazolopyridazine Inhibitor. | 3cd8 | 89.91 |
| 22 | 0jj | Crystal structure of c-Met in complex with triazolopyridazine inhibitor 2 | 4deg | 89.85 |
| 23 | 6xe | X-ray Structure of c-Met kinase in complex with inhibitor 6-((6-(4- fluorophenyl)-(1,2,4)triazolo(4,3-b)(1,2,4)triazin-3-yl)methyl) quinoline. | 3zbx | 89.85 |
| 24 | b2d | Crystal structure of c-Met with triazolopyridazine inhibitor 13 | 3i5n | 89.35 |
| 25 | ckk | Crystal structure of the tyrosine kinase domain of the hepatocyte growth factor receptor c-MET in complex with a Pyrrolotriazine based inhibitor | 3c1x | 87.33 |
| 26 | 0jk | Crystal structure of c-Met in complex with triazolopyridinone inhibitor 3 | 4deh | 87.2 |
| 27 | 4k0 | Crystal structure of C-MET kinase domain in complex with 4-(3-((1H- pyrrolo(2,3-b)pyridin-3-yl)methyl)-(1,2,4)triazolo(4,3-b)(1,2,4) triazin-6-yl)benzonitrile | 4aoi | 86.89 |
| 28 | 75h | Crystal structure of the c-Met kinase domain in complex with a pyrazolone inhibitor | 5t3q | 85.06 |
| 29 | 0jl | Crystal structure of c-Met in complex with triazolopyridinone inhibitor 24 | 4dei | 84.62 |
| 30 | 5t1 | Crystal structure of c-Met in complex with AMG 337 | 5eyd | 82.81 |
| 31 | 84m | MET Tyrosine Kinase Inhibition Enhances the Antitumor Efficacy of an HGF Antibody | 5uab | 82.73 |
| 32 | 44x | Crystal structure of c-Met in complex with (S)-5-(8-fluoro-3-(1-(3-(2-methoxyethoxy)quinolin-6-yl)ethyl)-[1,2,4]triazolo[4,3-a]pyridin-6-yl)-3-methylisoxazole | 4xyf | 82.62 |
| 33 | 84p | MET Tyrosine Kinase Inhibition Enhances the Antitumor Efficacy of an HGF Antibody | 5uaf | 82.15 |
| 34 | 84p | MET Tyrosine Kinase Inhibition Enhances the Antitumor Efficacy of an HGF Antibody | 5uad | 82.15 |
| 35 | 66l | Crystal structure of c-Met kinase domain in complex with LXM108 | 5hti | 81.41 |
| 36 | 88z | Crystal structure of D1228V cMET bound by foretinib | 6sdc | 81.07 |
| 37 | dfq | human c-MET kinase domain complexed with 6-benzyloxyquinoline inhibitor | 3a4p | 80.73 |
| 38 | 0j3 | Crystal structure of CMET in complex with novel inhibitor | 4gg5 | 80 |
| 39 | vgh | X-ray Structure of PF-02341066 bound to the kinase domain of c-Met | 2wgj | 78.4 |
| 40 | 88z | Structure of the kinase domain of c-Met bound to XL880 (GSK1363089) | 3lq8 | 78.26 |
| 41 | 1jc | Structure of dually phosphorylated c-MET receptor kinase in complex with an MK-8033 analog | 4iwd | 77.36 |
| 42 | 1ru | C-Met in complex with OSI ligand | 4knb | 76.9 |
| 43 | 88z | Crystal structure of wild-type cMET bound by foretinib | 6sd9 | 76.56 |
| 44 | 3eh | Identification and optimization of pyridazinones as potent and selective c-Met kinase inhibitor | 4r1y | 76.36 |
| 45 | 3e8 | Identification and optimization of pyridazinones as potent and selective c-Met kinase inhibitors | 4r1v | 75.3 |
| 46 | am7 | x-ray structure of c-Met with inhibitor. | 2rfn | 74.16 |
| 47 | 0j8 | Crystal structure of cMET in complex with novel inhibitor | 4gg7 | 73 |
| 48 | 63b | CRYSTAL STRUCTURE OF CMET WT with compound 3 | 5hni | 72.92 |
| 49 | ihx | Human c-Met Kinase in complex with quinoxaline inhibitor | 3f66 | 72.8 |
| 50 | q6w | Structure of dually-phosphorylated MET receptor kinase in complex with an MK-2461 analog with specificity for the activated receptor | 3q6w | 71.48 |
| 51 | m61 | Structure of dually phosphorylated c-MET receptor kinase in complex with an MK-2461 analog | 3r7o | 71.47 |
| 52 | 62e | Crystal structure of c-Met mutant Y1230H in complex with compound 14 | 5hlw | 64.73 |
| 53 | 63k | Crystal structure of c-Met-M1250T in complex with SAR125844. | 5hor | 60.22 |
| 54 | 63k | Crystal structure of c-Met L1195V in complex with SAR125844 | 5hoa | 59.78 |
| 55 | 63k | CRYSTAL STRUCTURE OF CMET IN COMPLEX WITH CMPD. | 5ho6 | 59.41 |