Index | Ligand Name | Structure | PDB code | ligand desolvation |
1 | 31w | The structure of TrkA kinase bound to the inhibitor 1-cyclopropyl-1-[3-(1,3-thiazol-2-yl)benzyl]-3-[4-(trifluoromethoxy)phenyl]urea | 4pmp | 93.19 |
2 | 6uk | TrkA JM-kinase with 1-(2-methyl-4-phenyl-pyrimidin-5-yl)-3-[[2-(trifluoromethyl)phenyl]methyl]urea | 5kmn | 91.92 |
3 | 31x | The structure of TrkA kinase bound to the inhibitor 4-naphthalen-1-yl-1-[(5-phenyl-1,2,4-oxadiazol-3-yl)methyl]-1H-pyrrolo[3,2-c]pyridine-2-carboxylic acid | 4pms | 91.84 |
4 | v4z | Human TrkA in complex with the inhibitor AZ-23 | 4aoj | 91.24 |
5 | 6k1 | Crystal structure of TrkA in complex with PF-05206283 | 5jfv | 91.13 |
6 | 6k2 | Crystal structure of TrkA in complex with PF-05247452 | 5jfw | 91.01 |
7 | 6uh | TrkA JM-kinase with 1-(5-methyl-3-phenyl-1,2-oxazol-4-yl)-3-[[2-(trifluoromethyl)phenyl]methyl]urea | 5kml | 90.87 |
8 | 6k4 | Crystal structure of TrkA in complex with PF-06273340 | 5jfx | 90.38 |
9 | god | Crystal structure of Trk-A in complex with the Pan-Trk Kinase Inhibitor, compound 19. | 6dki | 90.3 |
10 | gxa | Crystal structure of Trk-A in complex with the Pan-Trk Kinase Inhibitor, compound 3. | 6dkw | 89.7 |
11 | 6k0 | Crystal structure of TrkA in complex with PF-00593174 | 5jfs | 89.59 |
12 | ooj | TRK-A IN COMPLEX WITH LIGAND 1B | 6pl1 | 89.52 |
13 | oom | TRK-A IN COMPLEX WITH LIGAND 1a | 6pl2 | 88.35 |
14 | fky | Crystal structure of Trk-A in complex with the Pan-Trk Kinase Inhibitor, compound 10b. | 6dkb | 86.3 |
15 | go7 | Crystal structure of Trk-A in complex with the Pan-Trk Kinase Inhibitor, compound 13b. | 6dkg | 86.26 |
16 | ood | TRK-A IN COMPLEX WITH LIGAND 2a | 6pl3 | 85.08 |
17 | 6um | TrkA JM-kinase with 1-(2-methyl-4-phenyl-pyrimidin-5-yl)-3-(2-pyridyl)urea | 5kmo | 83.01 |
18 | 69c | TrkA with (6~{R})-3-methylsulfanyl-6-phenyl-1-(1~{H}-pyrazol-3-yl)-6,7-dihydro-5~{H}-thieno[3,4-c]pyridin-4-one | 5i8a | 82.41 |
19 | l0p | TRK-A IN COMPLEX WITH LIGAND 9 | 6nsp | 81.89 |
20 | 31y | The structure of TrkA kinase bound to the inhibitor N~4~-(4-morpholin-4-ylphenyl)-N~6~-(pyridin-3-ylmethyl)pyrido[3,2-d]pyrimidine-4,6-diamine | 4pmt | 81.83 |
21 | ymx | THE STRUCTURE OF TRKA KINASE DOMAIN BOUND TO THE INHIBITOR ENTRECTINIB | 5kvt | 79.78 |