| Index | Ligand Name | Structure | PDB code | ligand desolvation |
| 1 | mr9 | Evolution of a highly Selective and Potent 2-(Pyridin-2-yl)-1,3,5-triazine Tie-2 Kinase Inhibitor | 2p4i | 88.78 |
| 2 | 3wr | Selection of fragments for kinase inhibitor design: decoration is key | 4x3j | 87.08 |
| 3 | muh | Synthesis, Structural Analysis, and SAR Studies of Triazine Derivatives as Potent, Selective Tie-2 Inhibitors | 2osc | 86.31 |
| 4 | qq1 | Structure of the Tie2 kinase domain in complex with a thiazolopyrimidine inhibitor | 2wqb | 78.53 |
| 5 | raj | Synthesis, Structural Analysis, and SAR Studies of Triazine Derivatives as Potent, Selective Tie-2 Inhibitors | 2oo8 | 77.03 |