The Ligandable Human Proteome

Vascular endothelial growth factor receptor 2

Index	Ligand Name	Structure	PDB code	ligand desolvation
1	608	Crystal structure of the VEGFR2 kinase domain in complex with a nicotinamide inhibitor	2p2i	96.08
2	706	Crystal structure of the VEGFR2 kinase domain in complex with motesanib	3efl	95.63
3	5t2	Human Vascular Endothelial Growth Factor Receptor 2 (KDR) Kinase Domain in complex with AAL993	5ew3	94.86
4	c92	Crystal structure of the VEGFR2 kinase domain in complex with a bisamide inhibitor	3cpb	94.4
5	276	Crystal structure of the VEGFR2 kinase domain in complex with a benzimidazole inhibitor	2qu5	94.09
6	42q	Crystal structure of human VEGFR2 kinase domain with a novel pyrrolopyrimidine inhibitor.	3vhe	93.32
7	a96	Crystal structure of the VEGFR2 kinase domain in complex with a benzisoxazole inhibitor	3dtw	93.26
8	bax	KDR in complex with ligand sorafenib	3wze	92.73
9	lev	KDR in complex with ligand lenvatinib	3wzd	92.5
10	bax	Crystal Structure of VEGFR2 (Juxtamembrane and Kinase Domains) in Complex with SORAFENIB (BAY 43-9006)	4asd	91.66
11	f82	Crystal structure of human KDR (VEGFR2) kinase domain in complex with AZD3229-analogue (compound 18)	6gqo	91.24
12	0ja	Crystal Structure of the Kinase domain of Human VEGFR2 with a [1,3]thiazolo[5,4-b]pyridine derivative	3vnt	90.29
13	f88	Crystal structure of human KDR (VEGFR2) kinase domain in complex with AZD3229-analogue (compound 23)	6gqp	90.08
14	03x	Crystal structure of the VEGFR2 kinase domain in complex with a pyrazolone inhibitor	3u6j	89.33
15	k11	Crystal structure of the VEGFR2 kinase domain in complex with a pyridyl-pyrimidine benzimidazole inhibitor	3ewh	89.3
16	av9	CRYSTAL STRUCTURE OF VEGFR2 (JUXTAMEMBRANE AND KINASE DOMAINS) IN COMPLEX WITH TIVOZANIB (AV-951)	4ase	89.09
17	f8b	Crystal structure of human KDR (VEGFR2) kinase domain in complex with AZD3229-analogue (compound 35)	6gqq	88.97
18	2rl	Crystal structure of the VEGFR2 kinase domain in complex with a 2,3-dihydro-1,4-benzoxazine inhibitor	2rl5	88.82
19	857	Crystal structure of the VEGFR2 kinase domain in complex with a benzoxazole inhibitor	2qu6	88.68
20	900	Crystal structure of the VEGFR2 kinase domain in complex with a naphthamide inhibitor	3b8q	88.63
21	887	Crystal structure of the VEGFR2 kinase domain in complex with a naphthamide inhibitor	3b8r	88.16
22	0kf	Crystal Structure of the Kinase domain of Human VEGFR2 with imidazo[1,2-b]pyridazine derivative	3vo3	85.69
23	axi	CRYSTAL STRUCTURE OF THE VEGFR2 KINASE DOMAIN IN COMPLEX WITH AXITINIB (AG-013736) (N-Methyl-2-(3-((E)-2-pyridin-2-yl-vinyl)-1H- indazol-6-ylsulfanyl)-benzamide)	4ag8	84.85
24	gig	Crystal structure of Vegfr2 with a benzimidazole-urea inhibitor	2oh4	84.81
25	raj	Crystal structure of the VEGFR2 kinase domain in complex with a benzamide inhibitor	3be2	83.56
26	lif	Vegfr2 in complex with a novel 4-amino-furo[2,3-d]pyrimidine	1ywn	81.97
27	aax	Crystal structure of VEGFR2 in complex with a 2-anilino-5-aryl-oxazole inhibitor	1y6b	79.97
28	00j	Crystal structure of the VEGFR2 kinase domain in complex with PF- 00337210 (N,2-dimethyl-6-(7-(2-morpholinoethoxy)quinolin-4-yloxy) benzofuran-3-carboxamide)	2xir	77.14
29	994	Crystal structure of the VEGFR2 kinase domain in complex with a pyridinyl-triazine inhibitor	2p2h	75.04
30	kim	Crystal structure of VEGFR2 in complex with a 3,4,5-trimethoxy aniline containing pyrimidine	3cjg	74.53
31	sav	Crystal structure of VEGFR2 in complex with a 3,4,5-trimethoxy aniline containing pyrimidine	3cjf	63.61
32	b49	CRYSTAL STRUCTURE OF VEGFR2 (JUXTAMEMBRANE AND KINASE DOMAINS) IN COMPLEX WITH SUNITINIB (SU11248) (N-2-diethylaminoethyl)-5-((Z)-(5- fluoro-2-oxo-1H-indol-3-ylidene)methyl)-2,4-dimethyl-1H-pyrrole-3- carboxamide)	4agd	63.6
33	xin	Structure of VEGFR2 kinase domain in complex with BIBF1120	3c7q	62.09