The Ligandable Human Proteome

Index	Ligand Name	Structure	PDB code	ligand desolvation
1	x22	Crystal structure of XIAP BIR3 domain in complex with a Smac-mimetic compound, Smac005	3clx	88.78
2	c3t	Crystal structure of XIAP-BIR3 in complex with a cIAP1-selective SM	6ey2	86.03
3	x23	Crystal Structure of XIAP BIR3 domain in complex with a Smac-mimetic compound, Smac010	3cm2	81.91
4	4yc	Fragment-Based Drug Discovery Targeting Inhibitor of Apoptosis Proteins: Compound 18	5c7c	74.16
5	4yl	Fragment-Based Drug Discovery Targeting Inhibitor of Apoptosis Proteins: Compound 20	5c84	70.87
6	4ye	Fragment-Based Drug Discovery Targeting Inhibitor of Apoptosis Proteins: Compound 7	5c7a	70.7
7	4yn	Fragment-Based Drug Discovery Targeting Inhibitor of Apoptosis Proteins: Compound 21	5c83	69.57
8	4yf	Fragment-Based Drug Discovery Targeting Inhibitor of Apoptosis Proteins: Compound 17	5c7d	69.28
9	7ht	Small Molecule inhibitors of IAP	5m6e	69.18
10	fue	Fragment Derived XIAP inhibitor	6h6r	65.94
11	7h9	Small Molecule inhibitors of IAP	5m6l	65.31
12	7h8	Small Molecule inhibitors of IAP	5m6m	64.81
13	7j6	Small Molecule inhibitors of IAP	5m6h	63.68
14	7hu	Small Molecule inhibitors of IAP	5m6f	62.22
15	bi6	XIAP BIR3 bound to a Smac Mimetic	2jk7	57.9
16	smk	Crystal structure of XIAP BIR3 domain in complex with a Smac-mimetic compound	3eyl	56.33
17	9jz	Crystal structure of XIAP BIR3 with CS3	3hl5	47.86