The Ligandable Human Proteome

Bromodomain-containing protein 4

Index	Ligand Name	Structure	PDB code	ligand desolvation
1	etu	Bivalent binding to BET bromodomains	5ad2	92.22
2	cpb	Crystal structure of the first bromodomain of human BRD4 in complex with FLAVOPIRIDOL	4o71	88.16
3	8ng	BRD4_Bromodomain1-A1376855	5uvw	87.95
4	b0q	Crystal structure of human BRD4(1) bromodomain in complex with UT22B	5oww	85.03
5	1m3	Crystal structure of the first bromodomain of human BRD4 in complex with TG101209	4o76	84.96
6	87p	BRD4_BD2_A-1359930	5uer	82.33
7	2ta	Crystal Structure of the first bromodomain of human BRD4 in complex with the inhibitor TG-101348	4ogj	82.1
8	87m	BRD4_BD2_A-1390146	5ueq	81.98
9	87g	BRD4_BD2_A-1395017	5ueo	81.18
10	0s6	Crystal structure of the second bromodomain of human BRD4 in complex with MS417 inhibitor	6duv	80.73
11	1h3	Crystal Structure of the first bromodomain of human BRD4 in complex with a 3,5-dimethylisoxazol ligand	4j0s	79.18
12	1h2	Crystal Structure of the first bromodomain of human BRD4 in complex with a 3,5-dimethylisoxazol ligand	4j0r	78.84
13	89d	BRD4_BD2_A-1497627	5uex	78.47
14	1qk	Crystal structure of the first bromodomain of human BRD4 in complex with DINACICLIB	4o70	78.29
15	rnk	N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH 4-chloro-2-methyl-5-(((3-methylthiophen-2-yl)methyl)amino)pyridazin-3(2H)-one	5mkz	78.29
16	9e3	Crystal Structure of the first bromodomain of human BRD4 in complex with 5-((4-fluoro-1H-imidazol-1-yl)methyl)quinolin-8-ol	6afr	78.29
17	5ou	FIRST DOMAIN OF HUMAN BROMODOMAIN BRD4 IN COMPLEX WITH INHIBITOR 3-(4-Chlorobenzyl)-7-ethyl-3,7-dihydropurine-2,6-dione	5eis	78.21
18	dyz	FIRST DOMAIN OF HUMAN BROMODOMAIN BRD4 IN COMPLEX WITH INHIBITOR F1	6fnx	78.19
19	25k	Crystal Structure of the first bromodomain of human BRD4 in complex with a 5-methyl-triazolopyrimidine ligand	4men	78.15
20	88m	BRD4_BD2_A-1412838	5uey	77.88
21	14z	Crystal Structure of the first bromodomain of human BRD4 in complex with a quinazoline ligand	4hbw	77.81
22	e5t	Crystal Structure of the first bromodomain of human BRD4 in complex with a 3,5-dimethylisoxazol ligand	6ft3	77.76
23	l26	First bromodomain of BRD4 bound to inhibitor XD26	5d24	77.64
24	e5q	Crystal Structure of the first bromodomain of human BRD4 in complex with a 3,5-dimethylisoxazol ligand	6fsy	77.45
25	5nv	First domain of human bromodomain BRD4 in complex with inhibitor 8-(5-Amino-1H-[1,2,4]triazol-3-ylsulfanylmethyl)-3-(4-chlorobenzyl)-7-ethyl-3,7-dihydropurine-2,6-dione	5ei4	77.34
26	8nv	BRD4_BD2_A-1454056	5uvt	77.26
27	30m	Crystal structure of the first bromodomain of human BRD4 in complex with Olinone	4qb3	77.21
28	8ns	BRD4 Bromodomain 2 with A-1457066	5uvv	77.1
29	79c	CRYSTAL STRUCTURE OF THE FIRST BROMODOMAIN OF HUMAN BRD4 IN COMPLEX WITH RO3280	5vbp	77.06
30	8o4	BRD4_BD2_A-1461028	5uvu	76.81
31	77x	Structure of the first bromodomain of BRD4 with a pyrazolo[4,3-c]pyridin fragment	5luu	76.71
32	hcc	Crystal structure of BRD4 in complex with isoliquiritigenin and DMSO (Cocktail No. 3)	6ajv	76.66
33	64s	Crystal structure of fragment bound with Brd4	5hq7	76.35
34	p9l	N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH 1,3-DIMETHYL-6-(MORPHOLINE- 4-SULFONYL)-1,2,3,4-TETRAHYDROQUINAZOLIN-2-ONE	4a9l	75.8
35	89j	BRD4_BD2-A-35165	5uf0	75.75
36	3x0	Discovery of benzotriazolo diazepines as orally-active inhibitors of BET bromodomains: Crystal structure of BRD4 with CPI-13	4x2i	75.67
37	56y	First bromodomain of BRD4 bound to inhibitor XD47	5d3t	75.53
38	foy	BRD4(BD1) complexed with 2759	6czv	75.41
39	14x	Crystal Structure of the first bromodomain of human BRD4 in complex with a quinazolin ligand	4hbx	75.34
40	62v	Crystal structure of the first bromodomain of human BRD4 bound to benzoisoxazoloazepine 3	5hm0	75.24
41	69g	BRD4 in complex with Cpd4 ((E)-3-(6-(but-2-en-1-yl)-7-oxo-6,7-dihydro-1H-pyrrolo[2,3-c]pyridin-4-yl)-N,N-dimethylbenzamide)	5i88	75.22
42	2n0	Crystal Structure of the first bromodomain of human BRD4 in complex with compound B13	4pce	75.19
43	2rf	Crystal structure of the first bromodomain of human BRD4 in complex with SB-409514	4o7a	74.99
44	08h	Crystal Structure of the first bromodomain of human BRD4 in complex with Alprazolam	3u5j	74.8
45	guj	BRD4 bromodomain 1 in complex with HYB157	6dl2	74.78
46	d7t	Human BRD4 C-terminal bromodomain with 1-(4-(3-methylbenzyl)-3,4-dihydroquinoxalin-1(2H)-yl)ethanone	6ffd	74.76
47	08k	Crystal Structure of the first bromodomain of human BRD4 in complex with a benzo-triazepine ligand (BzT-7)	3u5l	74.59
48	2rj	Crystal structure of the first bromodomain of human BRD4 in complex with SB-284847-BT	4o7b	74.21
49	e0k	Crystal Structure Analysis of the BRD4	5yqx	74.08
50	7uu	Complex structure of the first bromodomain of BRD4 with an inhibitor that containing a 2H-chromen-2-one ring	5wuu	73.85
51	fp7	BRD4(BD1) complexed with 3219	6czu	73.5
52	89g	BRD4_BD2_A-1342843	5uez	73.45
53	h4c	Discovery of Epigenetic Regulator I-BET762: Lead Optimization to Afford a Clinical Candidate Inhibitor of the BET Bromodomains	4c66	73.32
54	rmr	Trimethoxy-ring inhibitor in complex with the first bromodomain of BRD4	5h21	73.17
55	a0r	Crystal structure of BRD4 in complex with 2',4'-dihydroxy-2-methoxychalcone	6ajy	73.08
56	e5w	Crystal Structure of the first bromodomain of human BRD4 in complex with a 3,5-dimethylisoxazol ligand	6ft4	72.84
57	2sj	Crystal Structure of BRD4(1) bound to Colchiceine	4lys	72.8
58	8f6	BRD4 bound with compound Bdi3	5xi3	72.71
59	5w4	Crystal structure of the first bromodomain of human BRD4 in complex with PNZ5 isoxazole inhibitor	5fbx	72.38
60	bmf	Crystal structure of the first bromodomain of human BRD4 in complex with bromosporine (BSP)	5igk	72.05
61	0q1	Crystal Structure of the first bromodomain of human BRD4 in complex with a isoxazolylbenzimidazole ligand	4gpj	72.04
62	6jf	N-terminal bromodomain of BRD4 in complex with OTX-015	5wmg	71.6
63	7e7	Crystal structure of BRD4 BROMODOMAIN 1 IN COMPLEX WITH LIGAND 2	5m3a	71.48
64	08j	Crystal Structure of the first bromodomain of human BRD4 in complex with Midazolam	3u5k	71.48
65	8nj	BRD4 Bromodomain 2 with A-1349391	5uvy	71.46
66	y81	Crystal structure of human BRD4(1) in complex with 4-[(5-phenylpyridin-3-yl)carbonyl]-3,4-dihydroquinoxalin-2(1H)-one (compound 19d)	4yh4	71.42
67	5v2	N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH N-(1,1-dioxo-1-thian-4-yl)- 5-methyl-4-oxo-7-3-(trifluoromethyl)phenyl-4H,5H-thieno-3,2-c- pyridine-2-carboximidamide	4uiy	71.39
68	13f	Crystal Structure of the first bromodomain of human BRD4 in complex with a quinazolin ligand	4hby	71.19
69	sav	Crystal structure of the first bromodomain of human BRD4 in complex with GW612286X	4o78	71.13
70	tvu	N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH 7-(3,4-dimethoxyphenyl)-N-(1,1-dioxo-1-thian-4-yl)-5-methyl-4-oxo-4H,5H-thieno-3,2-c-pyridine-2- carboxamide	4uix	71.06
71	96x	The first bromodomain of BRD4 with compound BDF-1253	5z5v	71.04
72	62g	Crystal structure of the first bromodomain of human BRD4 bound to CPI-0610	5hls	70.95
73	r78	Crystal Structure of the first bromodomain of human BRD4 in complex with the inhibitor BI-2536	4ogi	70.76
74	2rq	Crystal structure of the first bromodomain of human BRD4 in complex with SB-251527	4o7f	70.6
75	57e	First bromodomain of BRD4 bound to inhibitor XD41	5d3p	70.56
76	8f9	BRD4 bound with compound Bdi2	5xi2	70.56
77	e0b	Crystal Structure of the first bromodomain of human BRD4 in complex with benzo[cd]indol-2(1H)-one ligand	5d0c	70.52
78	5w0	Crystal structure of the first bromodomain of human BRD4 in complex with MA4-022-1	5f61	70.48
79	87s	BRD4_BD2_A-1344772	5ues	70.39
80	8f0	BRD4 bound with compound Bdi4	5xi4	70.34
81	6rx	CRYSTAL STRUCTURE OF THE FIRST BROMODOMAIN OF HUMAN BRD4 IN COMPLEX WITH A DIHYDROPYRIDOPYRIMIDINE SCAFFOLD INHIBITOR	5kdh	70.32
82	jqy	Crystal structure of the first bromodomain of human BRD4 in complex with SKT-68, a 1,4,5-trisubstituted imidazole analogue	6mh7	70.27
83	8xx	Crystal structure of BRD4-BD1 bound with hjp64	5you	70.27
84	jqp	CRYSTAL STRUCTURE OF THE FIRST BROMODOMAIN OF HUMAN BRD4 IN COMPLEX WITH HU-10, A 1,4,5-Trisubstituted Imidazole Analogue	6mh1	70.25
85	5vy	Crystal structure of the first bromodomain of human BRD4 in complex with MA2-014	5f5z	70.18
86	8xr	Crystal structure of BRD4-BD1 bound with hjp126	5yov	70.14
87	wdr	Crystal Structure of the first bromodomain of human BRD4 in complex with a dihydro-quinazolin ligand	3svf	69.57
88	l40	First bromodomain of BRD4 bound to inhibitor XD40	5d3n	69.53
89	hcc	Crystal structure of BRD4 in complex with isoliquiritigenin in the absence of DMSO	6ajx	69.42
90	4v1	Crystal structure of hBRD4 in complex with BL-BI06 reveals a novel synthesized inhibitor that induces Beclin1-independent/ATG5-dependent autophagic cell death in breast cancer	4zw1	69.22
91	1gh	Crystal Structure of the first bromodomain of human BRD4 in complex with I-BET151(GSK1210151A)	3zyu	69.2
92	1xb	Structure of BRD4 bromodomain 1 with a dimethyl thiophene isoxazole azepine carboxamide	4lrg	68.9
93	579	First bromodomain of BRD4 bound to inhibitor XD44	5d3s	68.86
94	eam	Crystal Structure of the First Bromodomain of Human Brd4 in complex with IBET inhibitor	3p5o	68.55
95	4ld	BRD4 bromodomain 2 in complex with gamma-carboline-containing compound, number 18.	4z93	68.46
96	78j	N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH 8-(3R,4R)-3-(cyclohexylmethoxy)piperidin-4-ylamino-3-methyl-1,2-dihydro-1,7- naphthyridin-2-one	5a85	67.8
97	wsh	Crystal Structure of the First Bromodomain of Human Brd4 with the inhibitor GW841819X	2yel	67.43
98	56m	First bromodomain of BRD4 bound to inhibitor XD27	5d25	67.37
99	wsh	Crystal Structure of the Second Bromodomain of Human Brd4 with the inhibitor GW841819X	2yem	67.3
100	0s6	Crystal structure of the first bromodomain of human BRD4 in complex with MS417 inhibitor	4f3i	67.09
101	8j2	Crystal structure of the first bromodomain of human BRD4 in complex with a tetrahydroquinoline analogue	5n2m	67.04
102	eo4	BRD4 BD1 in complex with compound CF53	6c7r	66.76
103	bnj	Brd4 Bromodomain 1 complex with its novel inhibitors	4qr3	66.64
104	jq1	Crystal Structure of the first bromodomain of human BRD4 in complex with the inhibitor JQ1	3mxf	66.54
105	y80	Crystal structure of human BRD4(1) in complex with 4-[(2E)-3-(4-methoxyphenyl)-2-phenylprop-2-enoyl]-3,4-dihydroquinoxalin-2(1H)-one (compound 19a)	4yh3	66.44
106	0s6	BRD4_BD2_A-1107604	5ueu	66.38
107	np8	NN-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH 5-5-methoxypyridin-3-yl-3- methyl-8-piperidin-4-ylamino-1,2-dihydro-1,7-naphthyridin-2-one	5a5s	66.19
108	9gy	Benzopiperazine BET bromodomain inhibitor in complex with BD1 of Brd4	5vom	65.48
109	eo1	BRD4 BD2 in complex with compound CE277	6c7q	65.23
110	bnm	Brd4 Bromodomain 1 complex with its novel inhibitors	4qr5	64.66
111	57g	First bromodomain of BRD4 bound to inhibitor XD29	5d3h	64.52
112	9bm	The first bromodomain of human BRD4 in complex with 3,5 dimethylisoxaxole ligand	4bw3	64.05
113	5d2	FIRST DOMAIN OF HUMAN BROMODOMAIN BRD4 IN COMPLEX WITH INHIBITOR N-{3-[4-(3-chlorophenyl)piperazin-1-yl]propyl}-1-{3-methyl-[1,2,4]triazolo[4,3-b]pyridazin-6-yl}piperidine-4-carboxamide	5dlx	63.95
114	l33	First bromodomain of BRD4 bound to inhibitor XD33	5d3j	63.76
115	bnk	Brd4 Bromodomain 1 complex with its novel inhibitors	4qr4	63.74
116	loc	Crystal structure of the first bromodomain of BRD4 in complex with 18-Crown-6	6in1	63.15
117	3p2	Crystal Structure of the first bromodomain of human BRD4 in complex with a novel inhibitor UMB32 (N-TERT-BUTYL-2-[4-(3,5-DIMETHYL-1,2-OXAZOL-4-YL) PHENYL]IMIDAZO[1,2-A]PYRAZIN-3-AMINE)	4wiv	63.1
118	73b	N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH GSK1324726A (I-BET726)	4bjx	63.08
119	loc	Crystal Structure of BRD4(1) bound to Colchicine	4lzr	63.01
120	9bm	A multiconformer ligand model of 3,5 dimethylisoxaxole bound to the bromodomain of human BRD4	6dml	62.83
121	57c	First bromodomain of BRD4 bound to inhibitor XD42	5d3r	62.75
122	21q	Crystal Structure of BRD4(1) bound to inhibitor XD14	4lyw	62.7
123	53w	A multiconformer ligand model of inhibitor 53W bound to CREB binding protein bromodomain	6dmj	62.7
124	loc	Joint nentron and X-ray structure of BRD4 in complex with colchicin	6ajz	62.67
125	l28	First bromodomain of BRD4 bound to inhibitor XD28	5d26	62.58
126	uth	The first bromodomain of human BRD4 in complex with 3,5 dimethylisoxaxole ligand	4bw2	62.36
127	5nq	FIRST DOMAIN OF HUMAN BROMODOMAIN BRD4 IN COMPLEX WITH INHIBITOR 3-Butyl-8-(6-butyl-5,7-dimethyl-[1,2,4]triazolo[1,5-a]pyrimidin-2-ylsulfanylmethyl)-7-ethyl-3,7-dihydropurine-2,6-dione	5egu	62.31
128	s5b	The first bromodomain of human BRD4 in complex with 3,5 dimethylisoxaxole ligand	4bw1	62.3
129	837	BRD4 first bromodomain (BD1) in complex with dual PI3 kinase (PI3K) inhibitor SF2535	5u2e	62.11
130	53w	Selective pharmacological inhibition of the CREB binding protein bromodomain regulates inflammatory cytokines in macrophages and RGS4 in neurons	5cfw	62.11
131	nue	Crystal structure of the first bromodomain of human BRD4 in complex with MS267 inhibitor	4nue	61.9
132	1k0	Crystal Structure of the first bromodomain of human BRD4 in complex with a quinazolinone ligand (RVX-OH)	4mr3	61.79
133	dzh	FIRST DOMAIN OF HUMAN BROMODOMAIN BRD4 IN COMPLEX WITH INHIBITOR #17	6fo5	61.75
134	3ot	Direct photocapture of bromodomains using tropolone chemical probes	4whw	61.51
135	82y	BRD4 first bromodomain (BD1) in complex with dual PI3 kinase (PI3K) inhibitor SF2558HA	5u2f	61.45
136	2re	Crystal structure of the first bromodomain of human BRD4 in complex with SB 202190	4o77	61.42
137	1k0	X-ray crystal structure of bromodomain complex to 1.24 A resolution	4j3i	61.36
138	ies	N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH I-BET295	4cl9	60.54
139	fze	N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH : 8-(((1R,2R,3R,5S)-2-(2-(4,4-difluorocyclohexyl)ethyl)-8-azabicyclo[3.2.1]octan-3-yl)amino)-3-methyl-5-(5-methylpyridin-3-yl)-1,7-naphthyridin-2(1H)-one	6hdq	60.32
140	x27	Crystal Structure of the first bromodomain of human BRD4 in complex with the inhibitor JWG056	6cj2	60.19
141	83t	N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH IBET-295	4clb	59.79
142	6xx	N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH 8-(((3R,4R,5S)-3-((4,4-difluorocyclohexyl)methoxy)-5-methoxypiperidin-4-yl)amino)-3-methyl-5-(5-methylpyridin-3-yl)-1,7-naphthyridin-2(1H)-one	5lj1	59.71
143	5w1	Crystal structure of the first bromodomain of human BRD4 in complex with MA4-022-2	5f62	59.56
144	hg8	Crystal structure of the first bromodomain of human BRD4 in complex with the inhibitor 16k	6q3z	59.53
145	2rk	Crystal structure of the first bromodomain of human BRD4 in complex with SB-614067-R	4o7c	59.2
146	1k0	Crystal Structure of the first bromodomain of human BRD4 in complex with a quinazolinone ligand (RVX-208)	4mr4	59.19
147	9s3	N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH 1-(2R,4S)-2-methyl-4-(phenylamino)-6-4-(piperidin-1-ylmethyl)phenyl-1,2,3,4- tetrahydroquinolin-1-yl-ethan-1-one	5acy	59.13
148	1a9	Brd4 Bromodomain 1 complex with 3-CYCLOHEXYL-N-{3-(2-OXO-2,3-DIHYDRO-1,3-THIAZOL-4-YL)-5-[(THIOPHEN-2-YLSULFONYL)AMINO]PHENYL}PROPANAMIDE inhibitor	4hxl	59.02
149	5vz	Crystal structure of the first bromodomain of human BRD4 in complex with SG3-014	5f60	58.95
150	n1d	N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH 7-(3,4-dimethoxyphenyl)-2-(4-methanesulfonylpiperazine-1-carbonyl)-5-methyl-4H,5H-thieno-3,2-c- pyridin-4-one	4uiz	58.89
151	2ll	Crystal structure of the first bromodomain of human BRD4 in complex with an isoxazolyl-benzimidazole ligand	4nr8	58.78
152	57f	First bromodomain of BRD4 bound to inhibitor XD35	5d3l	58.52
153	6je	N-terminal bromodomain of BRD4 in complex with OTX-015	5wmd	58.19
154	ay2	Crystal structure of human BRD4(1) bromodomain in complex with DR46	5ovb	58.17
155	6xh	BRD4 bromodomain in complex with Cpd59 ((S)-1-(3-((2-fluoro-4-(1-methyl-1H-pyrazol-4-yl)phenyl)amino)-1-(tetrahydrofuran-3-yl)-6,7-dihydro-1H-pyrazolo[4,3-c]pyridin-5(4H)-yl)ethanone)	5ku3	58.11
156	8q9	Crystal Structure Analysis of the BRD4	5y93	57.45
157	2ta	Crystal structure of the first bromodomain of human BRD4 in complex with TG101348	4ps5	56.6
158	5mj	Crystal Structure of the First Bromodomain of Human BRD4 in Complex With Cyclic Vinylogous Amide Inhibitor MS402	5ula	56.2
159	hg5	Crystal structure of the first bromodomain of human BRD4 in complex with the inhibitor 16i	6q3y	56.01
160	ksz	Crystal Structure of the first bromodomain of BRD4 in complex with a benzodiazepine ligand	6s25	55.44
161	6tb	CRYSTAL STRUCTURE OF THE FIRST BROMODOMAIN OF HUMAN BRD4 IN COMPLEX WITH DB-1-264-2	5kj0	54.68
162	jbs	Crystal structure of human BRD4(1) in complex with CN210 (compound 19)	6mau	54.67
163	6xw	N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH 5-(5-aminopyridin-3-yl)-8-(((3R,4R)-3-((1,1-dioxidotetrahydro-2H-thiopyran-4-yl)methoxy)piperidin-4-yl)amino)-3-methyl-1,7-naphthyridin-2(1H)-one	5lj2	53.64
164	4k4	CRYSTAL STRUCTURE OF THE FIRST BROMODOMAIN OF HUMAN BRD4 IN COMPLEX WITH LRRK2-IN-1	5vbo	53.53
165	hry	Crystal structure of human BRD4(1) in complex with CN750	6e4a	52.67
166	4wg	BRD4 in complex with ERK5 inhibitor XMD8-92	5lrq	52.42
167	5d1	FIRST DOMAIN OF HUMAN BROMODOMAIN BRD4 IN COMPLEX WITH INHIBITOR 4-[(1-methyl-2-oxo-1,2-dihydroquinolin-4-yl)oxy]-N-({1-[(3-methylphe methyl]piperidin-4-yl}methyl)butanamide	5dlz	52
168	5gd	X-ray crystal structure of human BRD4(BD1) in complex with RVX297 to 1.12 A resolution	5dw2	51.78
169	9u4	BRD4-BD1 in complex with Cpd19 (3-(7-(difluoromethyl)-6-(1-methyl-1H-pyrazol-4-yl)-3,4-dihydroquinolin-1(2H)-yl)-N-methyl-1-(tetrahydro-2H-pyran-4-yl)-1,4,6,7-tetrahydro-5H-pyrazolo[4,3-c]pyridine-5-carboxamide)	5vzs	49.58
170	ex1	Crystal Structure of the first bromodomain of human BRD4 in complex with the inhibitor JWG046	6cd4	48.44
171	2lo	Crystal structure of BRD4 first bromodomain in complex with SGC-CBP30 chemical probe	5bt4	48.4
172	x30	Crystal Structure of the first bromodomain of human BRD4 in complex with the inhibitor JWG048	5w55	48.2
173	4k4	Crystal Structure of the first bromodomain of human BRD4 in complex with the inhibitor XMD11-50	5wa5	47.47
174	r78	Crystal structure of the first bromodomain of human BRD4 in complex with BI 2536	4o74	45.7