| Index | Ligand Name | Structure | PDB code | ligand desolvation |
| 1 | rv1 | The crystal structure of H-Ras and SOS in complex with ligands | 4ury | 95.78 |
| 2 | fvy | Ras:SOS:Ras in complex with a small molecule activator | 6d5v | 89.97 |
| 3 | bq5 | Ras guanine nucleotide exchange factor SOS1 (Rem-cdc25) in complex with KRAS(G12C) and fragment screening hit F1 | 6epm | 89.15 |
| 4 | fw7 | Ras:SOS:Ras in complex with a small molecule activator | 6d5l | 87.69 |
| 5 | fvv | Ras:SOS:Ras in complex with a small molecule activator | 6d5w | 85.74 |
| 6 | fw4 | Ras:SOS:Ras in complex with a small molecule activator | 6d5m | 85.17 |
| 7 | fv4 | Ras:SOS:Ras in complex with a small molecule activator | 6d5j | 85.11 |
| 8 | fvg | Ras:SOS:Ras in complex with a small molecule activator | 6d5e | 84.81 |
| 9 | 5ux | Ligand-bound Ras:SOS:Ras complex | 5wfp | 84.34 |
| 10 | 5uv | Ligand-bound Ras:SOS:Ras complex | 5wfq | 83.73 |
| 11 | 5uu | Ligand-bound Ras:SOS:Ras complex | 5wfo | 83.35 |
| 12 | fvd | Ras:SOS:Ras in complex with a small molecule activator | 6d5g | 81.31 |
| 13 | fvj | Ras:SOS:Ras in complex with a small molecule activator | 6d59 | 81.31 |
| 14 | fv7 | Ras:SOS:Ras in complex with a small molecule activator | 6d5h | 81.09 |
| 15 | ffv | Ras:SOS:Ras in complex with a small molecule activator | 6cup | 79.93 |
| 16 | ffs | Ras:SOS:Ras in complex with a small molecule activator | 6cuo | 79.02 |
| 17 | axh | Ras guanine nucleotide exchange factor SOS1 (Rem-cdc25) in complex with small molecule inhibitor BAY-293 (compound 23) | 5ovi | 75.75 |
| 18 | 5uw | Ligand-bound Ras:SOS:Ras complex | 5wfr | 75.57 |
| 19 | aww | Ras guanine nucleotide exchange factor SOS1 (Rem-cdc25) in complex with small molecule inhibitor compound 21 | 5ovh | 73.8 |
| 20 | ffy | Ras:SOS:Ras in complex with a small molecule activator | 6cur | 73.72 |
| 21 | fwa | Ras:SOS:Ras in complex with a small molecule activator | 6d55 | 73.47 |
| 22 | awt | Ras guanine nucleotide exchange factor SOS1 (Rem-cdc25) in complex with small molecule inhibitor compound 17 | 5ovf | 72.5 |
| 23 | axe | Ras guanine nucleotide exchange factor SOS1 (Rem-cdc25) in complex with small molecule inhibitor compound 1 | 5ove | 69.03 |
| 24 | awz | Ras guanine nucleotide exchange factor SOS1 (Rem-cdc25) in complex with small molecule inhibitor compound 18 | 5ovg | 67.91 |
| 25 | ec4 | Ras:SOS:Ras in complex with a small molecule activator | 6bvi | 67.38 |
| 26 | 2px | Approach for Targeting Ras with Small Molecules that Activate SOS-Mediated Nucleotide Exchange | 4nyi | 66.58 |
| 27 | ebv | Ras:SOS:Ras in complex with a small molecule activator | 6bvm | 64.26 |
| 28 | eby | Ras:SOS:Ras in complex with a small molecule activator | 6bvl | 63.87 |
| 29 | eav | Ras:SOS:Ras in complex with a small molecule activator | 6bvk | 63.12 |
| 30 | eas | Ras:SOS:Ras in complex with a small molecule activator | 6bvj | 62.91 |
| 31 | 2pz | Approach for Targeting Ras with Small Molecules that Activate SOS-Mediated Nucleotide Exchange | 4nyj | 56.44 |