The Ligandable Human Proteome

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Integrin alpha-L

von Willebrand factor, type A

IndexLigand NameStructurePDB codeligand desolvation
1la1X-ray structure of LFA-1 I-domain bound to a 1,4-diazepane-2,5-dione inhibitor at 1.8A resolution1xuo89.2
2bqnLFA-1 I domain bound to inhibitors3bqn88.5
3bqmLFA-1 I domain bound to inhibitors3bqm86.42
4803CRYSTAL STRUCTURE ANALYSIS OF THE COMPLEX LFA-1 (CD11A) I-DOMAIN / LOVASTATIN AT 2.6 A RESOLUTION1cqp79.39
52icCD11a (LFA1) I-domain complexed with BMS-587101 aka 5-[(5S, 9R)-9-(4-cyanophenyl)-3-(3,5-dichlorophenyl)-1-methyl-2,4-dioxo-1,3,7-triazaspiro [4.4]non-7-yl]methyl]-3-thiophenecarboxylicacid2ica74.99
6ab8X-ray structure of LFA-1 I-domain in complex with LFA878 at 2.1A resolution1xdg66.83