The Ligandable Human Proteome

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Cellular tumor antigen p53

p53, DNA-binding domain

IndexLigand NameStructurePDB codeligand desolvation
19gtp53 cancer mutant Y220C im complex with compound MB5775o1e86
29gwp53 cancer mutant Y220C in complex with compound MB4815o1d85.01
39h2p53 cancer mutant Y220C in complex with compound MB845o1b84.47
49gnp53 cancer mutant Y220C in complex with compound MB5395o1h84.25
59gqp53 cancer mutant Y220C in complex with compound MB5825o1f83.5
6y0vStructure of the p53 cancer mutant Y220C in complex with 2-hydroxy-3, 5-diiodo-4-(1H-pyrrol-1-yl)benzoic acid5aoj83.02
79gzp53 cancer mutant Y220C in complex with compound MB1845o1c82.17
8fy8Structure of the p53 cancer mutant Y220C with bound small molecule PhiKan8835aom79.75
99ghp53 cancer mutant Y220C in complex with compound MB7105o1i79.11
1092oStructure of the p53 cancer mutant Y220C with bound small molecule 7- ethyl-3-(piperidin-4-yl)-1H-indole5ab978.33
11qc5Structure of the p53 core domain mutant Y220C bound to the small molecule PhiKan72423zme77.94
129gkp53 cancer mutant Y220C in complex with compound MB4875o1g77.81
13p84Structure of the p53 core domain mutant Y220C bound to the stabilizing small molecule PhiKan7844agl77.37
149h5p53 cancer mutant Y220C in complex with compound MB2405o1a73.39
15nxgStructure of the p53 core domain mutant Y220C bound to the stabilizing small molecule PhiKan51164agn66.29
16p86Structure of the p53 core domain mutant Y220C bound to the stabilizing small molecule PhiKan50864agm61.28
17ul7Structure of the p53 cancer mutant Y220C with bound small-molecule stabilizer PhiKan51495aba60.12
18kmnStructure of the p53 cancer Y220C bound to the stabilizing small molecule PhiKan52115a7b59.71
19p96Structure of the p53 core domain mutant Y220C bound to the stabilizing small molecule PhiKan51964agq59.57
20p51Structure of the p53 core domain mutant Y220C bound to the stabilizing small molecule PhiKan51764agp59.2
21p74Structure of the p53 core domain mutant Y220C bound to the stabilizing small molecule PhiKan51744ago57.24