| Index | Ligand Name | Structure | PDB code | ligand desolvation |
| 1 | dgr | Crystal structure of human FTO in complex with acylhydrazine inhibitor 21 | 4cxy | 95.82 |
| 2 | nkg | Crystal structure of an oxygenase in complex with inhibitor cco010 | 4qho | 94.07 |
| 3 | un9 | Crystal structure of the human fat mass and obesity associated protein (FTO) in complex with N-[(1-chloro-4-hydroxyisoquinolin-3-yl)carbonyl]glycine (IOX3/UN9) | 4ie6 | 93.78 |
| 4 | 640 | Crystal structure of human FTO in complex with acylhydrazine inhibitor 16 | 4cxx | 93.13 |
| 5 | pd9 | Crystal structure of human FTO in complex with small-molecule inhibitors | 6ak4 | 92.83 |
| 6 | 7yc | Crystal structure of human FTO in complex with small-molecule inhibitors | 6aej | 91.84 |
| 7 | 8s3 | Crystal structure of RNA dioxygenase bound with an inhibitor | 6akw | 87.94 |
| 8 | 3dt | Crystal structure of the fat mass and obesity associated (FTO) protein reveals basis for its substrate specificity | 3lfm | 85.7 |
| 9 | jms | Crystal structure of FTO bound to a selective inhibitor | 4qkn | 83.84 |
| 10 | rhn | Crystal structure of the human fat mass and obesity associated protein (FTO) in complex with citrate and rhein (RHN) | 4ie7 | 83.35 |
| 11 | 58w | Crystal structure of FTO-IN115 | 5dab | 70.3 |