| Index | Ligand Name | Structure | PDB code | ligand desolvation |
| 1 | cux | Discovery of Potent and Selective Covalent Protein Arginine Methyltransferase (PRMT5) Inhibitors | 6k1s | 99.02 |
| 2 | mta | Crystal Structure of PRMT5:MEP50 in complex with MTA and H4 peptide | 5fa5 | 98.22 |
| 3 | f5j | Structure of PRMT5:MEP50 in complex with LLY-283, a potent and selective inhibitor of PRMT5, with antitumor activity | 6ckc | 96.87 |
| 4 | 4z2 | Crystal structure of PRMT5:MEP50 with EPZ015866 and sinefungin | 5c9z | 94.37 |
| 5 | 3xv | Crystal structure of PRMT5:MEP50 with EPZ015666 and sinefungin | 4x60 | 93.42 |
| 6 | 5qh | Crystal structure of PRMT5:MEP50 with Compound 9 and sinefungin | 5emk | 92.12 |
| 7 | 5qk | Crystal structure of PRMT5:MEP50 with Compound 10 and SAM | 5eml | 91.76 |
| 8 | 3xv | Crystal structure of PRMT5:MEP50 with EPZ015666 and SAM | 4x61 | 91.59 |
| 9 | 5ql | Crystal structure of PRMT5:MEP50 with Compound 15 and sinefungin | 5emm | 91.47 |
| 10 | 5qj | Crystal structure of PRMT5:MEP50 with Compound 8 and sinefungin | 5emj | 89.91 |