The Ligandable Human Proteome

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RAC-alpha serine/threonine-protein kinase

Protein kinase domain

IndexLigand NameStructurePDB codeCompound Potency nM
1wfeCrystal structure of Akt-1-inhibitor complexes3mvh0.5
20xzPKB alpha in complex with AZD53634gv13
3smyDiscovery of dihydrothieno- and dihydrofuropyrimidines as potent pan Akt inhibitors3ow422
4sm9Spirocyclic sulfonamides as AKT inhibitors3qkm38
5xfeCrystal structure of Akt-1-inhibitor complexes3mv5180