| Index | Ligand Name | Structure | PDB code | Compound Potency nM |
| 1 | s25 | Crystal structure of Chk1 in complex with inhibitor S25 | 3tki | 0.05 |
| 2 | 710 | crystal structure of Chek1 in complex with inhibitor 20 | 2hog | 0.3 |
| 3 | 12c | 4-(Aminoalkylamino)-3-Benzimidazole-Quinolinones As Potent CHK1 Inhibitors | 2gdo | 0.32 |
| 4 | 306 | crystal structure of chek1 in complex with inhibitor 22 | 2hy0 | 0.65 |
| 5 | m54 | Crystal Structure of Chek1 in Complex with Inhibitor 54 | 2r0u | 1 |
| 6 | c70 | X-ray crystal structure of compound 70 bound to human CHK1 kinase domain | 3pa3 | 1 |
| 7 | 1am | X-RAY Crystal structure of compound 39 bound to human chk1 kinase domain | 4hyh | 1 |
| 8 | 3x7 | CHK1 kinase domain with diazacarbazole compound 19 | 4rvm | 1 |
| 9 | c73 | X-ray crystal structure of compound 1 bound to human CHK1 kinase domain | 3pa5 | 2 |
| 10 | c72 | X-ray crystal structure of compound 2a bound to human CHK1 kinase domain | 3pa4 | 3 |
| 11 | 1ao | X-RAY Crystal structure of compound 40 bound to human chk1 kinase domain | 4hyi | 3 |
| 12 | 3dw | CHK1 kinase domain in complex with diazacarbazole compound 14 | 4qyg | 4.1 |
| 13 | 5cv | Identification of Novel, in vivo Active Chk1 Inhibitors Utilizing Structure Guided Drug Design | 5dls | 4.4 |
| 14 | 22k | X-ray crystal structure of compound 22k bound to human Chk1 kinase domain | 3ot3 | 5 |
| 15 | ydj | Discovery of Checkpoint Kinase Inhibitor AZD7762 by Structure Based Design and Optimization of Thiophene Carboxamide Ureas | 2ydj | 5 |
| 16 | 76a | Structure of h-CHK1 complexed with A767085 | 2e9n | 6.2 |
| 17 | ydk | Discovery of Checkpoint Kinase Inhibitor AZD7762 by Structure Based Design and Optimization of Thiophene Carboxamide Ureas | 2ydk | 7 |
| 18 | a25 | Structure of h-CHK1 complexed with A780125 | 2e9u | 7.94 |
| 19 | mi5 | X-ray crystal structure of compound 17r bound to human Chk1 kinase domain | 3ot8 | 9 |
| 20 | 422 | crystal structure of Chek1 in complex with inhibitor 1 | 2hxl | 12 |
| 21 | 85a | Structure of h-CHK1 complexed with A859017 | 2e9v | 12.59 |
| 22 | ym8 | Crystal structure of checkpoint kinase 1 (Chk1) in complex with inhibitors | 2ym8 | 13 |
| 23 | x8e | Discovery of a Novel Class of triazolones as Checkpoint Kinase Inhibitors - Hit to Lead Exploration | 2x8e | 14 |
| 24 | 1ko | X-RAY Crystal structure of compound 22a (R)-2-(4-chlorophenyl)-8-(piperidin-3-ylamino)imidazo[1,2-c]pyrimidine-5-carboxamide bound to human chk1 kinase domain | 4jik | 18 |
| 25 | a58 | Structure of h-CHK1 complexed with AA582939 | 2e9o | 20 |
| 26 | 5be | Novel kinase profile highlights the temporal basis of context dependent checkpoint pathways to cell death | 3nlb | 35 |
| 27 | 07s | Crystal structure of Chk1 in complex with inhibitor S01 | 3tkh | 47 |
| 28 | 09h | X-ray crystal structure of compound 1 bound to human CHK1 kinase domain | 3u9n | 100 |
| 29 | 373 | crystal structure of Chek1 in complex with inhibitor 2 | 2hxq | 144 |
| 30 | ydi | Discovery of Checkpoint Kinase Inhibitor AZD7762 by Structure Based Design and Optimization of Thiophene Carboxamide Ureas | 2ydi | 150 |
| 31 | x8i | Discovery of a Novel Class of triazolones as Checkpoint Kinase Inhibitors - Hit to Lead Exploration | 2x8i | 190 |
| 32 | zyw | Crystal structure of checkpoint kinase 1 (Chk1) in complex with inhibitors | 2wmw | 390 |
| 33 | ym5 | Crystal structure of checkpoint kinase 1 (Chk1) in complex with inhibitors | 2ym5 | 430 |
| 34 | 7cs | crystal structure of Chek1 in complex with inhibitor 2a | 2qhm | 660 |
| 35 | zy6 | Crystal structure of checkpoint kinase 1 (Chk1) in complex with inhibitors | 2wmx | 860 |
| 36 | ym6 | Crystal structure of checkpoint kinase 1 (Chk1) in complex with inhibitors | 2ym6 | 880 |
| 37 | ym3 | Crystal structure of checkpoint kinase 1 (Chk1) in complex with inhibitors | 2ym3 | 1000 |
| 38 | 3dl | CHK1 kinase domain in complex with diarylpyrazine compound 1 | 4qye | 1200 |
| 39 | 38m | Crystal structure of chk1 kinase in complex with inhibitor 38 | 3f9n | 1300 |
| 40 | df2 | Structure-based Design of Novel Chk1 Inhibitors: Insights into Hydrogen Bonding and Protein-Ligand Affinity | 2bro | 1400 |
| 41 | 4ym | Crystal structure of checkpoint kinase 1 (Chk1) in complex with inhibitors | 2ym4 | 1500 |
| 42 | agx | Characterization of the Chk1 allosteric inhibitor binding site | 3jvr | 1890 |
| 43 | df1 | Structure-based Design of Novel Chk1 Inhibitors: Insights into Hydrogen Bonding and Protein-Ligand Affinity | 2brn | 5500 |
| 44 | dfy | Structure-based Design of Novel Chk1 Inhibitors: Insights into Hydrogen Bonding and Protein-Ligand Affinity | 2brg | 6100 |
| 45 | pfp | Structure-based Design of Novel Chk1 Inhibitors: Insights into Hydrogen Bonding and Protein-Ligand Affinity | 2br1 | 7200 |
| 46 | zyv | Crystal structure of checkpoint kinase 1 (Chk1) in complex with inhibitors | 2wmv | 9200 |
| 47 | pfq | Structure-based Design of Novel Chk1 Inhibitors: Insights into Hydrogen Bonding and Protein-Ligand Affinity | 2brb | 1.37e+004 |
| 48 | 3d3 | Identification of chemically diverse Chk1 inhibitors by receptor- based virtual screening | 2cgx | 1.56e+004 |
| 49 | dfw | Structure-based Design of Novel Chk1 Inhibitors: Insights into Hydrogen Bonding and Protein-Ligand Affinity | 2brh | 2.29e+004 |
| 50 | zyr | Crystal structure of checkpoint kinase 1 (Chk1) in complex with inhibitors | 2wmr | 5.2e+004 |