The Ligandable Human Proteome

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Mitogen-activated protein kinase kinase kinase kinase 4

Protein kinase domain

IndexLigand NameStructurePDB codeCompound Potency nM
14p4MAP4K4 in complex with inhibitor GNE-4954zk53.7
23d9MAP4K4 in complex with inhibitor (compound 16)4u448
33dcMAP4K4 in complex with inhibitor (compound 25)4u4510
45dfMAP4K4 in complex with an inhibitor5di121
52qtMAP4K4 in complex with inhibitor (compound 31), N-[3-(4-AMINOQUINAZOLIN-6-YL)-5-FLUOROPHENYL]-2-(PYRROLIDIN-1-YL)ACETAMIDE4obq65
63xmMAP4K4 in complex with a pyridin-2(1H)-one derivative4rvt1900
73d8MAP4K4 in complex with inhibitor (compound 6)4u434.8e+004