| Index | Ligand Name | Structure | PDB code | Compound Potency nM |
| 1 | 2ol | Back pocket flexibility provides group-II PAK selectivity for type 1 kinase inhibitors | 4o0v | 3.3 |
| 2 | 2oo | Back pocket flexibility provides group-II PAK selectivity for type 1 kinase inhibitors | 4o0y | 60 |
| 3 | n53 | Crystal Structure of the Human p21-Activated Kinase 4 in Complex with (S)-N-(5-(3-benzyl-1-methylpiperazine-4-carbonyl)-6,6-dimethyl-1,4,5, 6-tetrahydropyrrolo(3,4-c)pyrazol-3-yl)-3-phenoxybenzamide | 4app | 64 |
| 4 | 2oq | Back pocket flexibility provides group-II PAK selectivity for type 1 kinase inhibitors | 4o0x | 68 |
| 5 | 4t6 | Crystal structure of P21-activated kinase 4 in complex with an inhibitor compound 29 | 5bms | 455 |
| 6 | 981 | PAK4 kinase domain in complex with FRAX486 | 5vee | 779 |