| Index | Ligand Name | Structure | PDB code | Compound Potency nM |
| 1 | abq | Discovery of a Novel, Potent and Selective Inhibitor of 3-Phosphoinositide Dependent Kinase (PDK1) | 3rwp | 0.6 |
| 2 | mp7 | PDK1 in complex with DFG-OUT inhibitor xxx | 3qc4 | 2 |
| 3 | 3q4 | Phosphoinositide-Dependent Kinase-1 (PDK1) kinase domain with (2R,5S)-1-[2-Amino-6-(3-amino-1H-indazol-6-yl)-4-pyrimidinyl]-6-methyl-N-phenyl-3-piperidinecarboxamide | 3qd0 | 3.16 |
| 4 | 464 | CRYSTAL STRUCTURE OF HUMAN PHOSPHOINOSITIDE-DEPENDENT PROTEIN KINASE 1 (PDK1) 3-{5-[2-Oxo-5-ureido-1,2-dihydro-indol-(3Z)-ylidenemethyl]-1H-pyrrol-3-yl}-N-(2-piperidin-1-yl-ethyl)-benzamide COMPLEX | 2pe2 | 4 |
| 5 | 517 | CRYSTAL STRUCTURE OF HUMAN PHOSPHOINOSITIDE-DEPENDENT PROTEIN KINASE 1 (PDK1) {2-Oxo-3-[1-(1H-pyrrol-2-yl)-eth-(Z)-ylidene]-2,3-dihydro-1H-indol-5-yl}-urea {BX-517} COMPLEX | 2pe1 | 5 |
| 6 | 8h1 | PDK1 in complex with Compound 8h | 3ion | 8 |
| 7 | 8i1 | PDK-1 in complex with the inhibitor Compound-8i | 3iop | 17 |
| 8 | 3q3 | Phosphoinositide-Dependent Kinase-1 (PDK1) kinase domain with 4-[2-Amino-6-(3-amino-1H-indazol-6-yl)-4-pyrimidinyl]-N-phenyl-2-morpholinecarboxamide | 3qcy | 20 |
| 9 | li8 | Crystal Structure Of N1-[3-[[5-bromo-2-[[3-[(1-pyrrolidinylcarbonyl)amino]phenyl]amino]-4-pyrimidinyl]amino]propyl]-2,2-dimethylpropanediamide Complexed with Human PDK1 | 1z5m | 30 |
| 10 | 3rw | Discovery of a Novel, Potent and Selective Inhibitor of 3-Phosphoinositide Dependent Kinase (PDK1) | 3rwq | 35 |
| 11 | 9bd | Phosphoinositide-dependent protein kinase 1 (PDK-1) in complex with compound 9 | 3h9o | 70 |
| 12 | ckg | Crystal structure of PDK1 in complex with a pyrazoloquinazoline inhibitor | 2xch | 374 |
| 13 | mh4 | Crystal structure of PDK1 in complex with a pyrazoloquinazoline inhibitor | 2xck | 713 |
| 14 | adn | Human PDK1 Kinase Domain in Complex with Adenosine Bound to the ATP-Binding Site | 5lvn | 2e+004 |